Aliases for BRK1 Gene
External Ids for BRK1 Gene
Previous HGNC Symbols for BRK1 Gene
Previous GeneCards Identifiers for BRK1 Gene
GeneCards Summary for BRK1 Gene
BRK1 (BRICK1, SCAR/WAVE Actin Nucleating Complex Subunit) is a Protein Coding gene. Diseases associated with BRK1 include Lung Squamous Cell Carcinoma. Among its related pathways are Signaling by Rho GTPases and G-protein signaling RAC1 in cellular process. Gene Ontology (GO) annotations related to this gene include Rac GTPase binding.
UniProtKB/Swiss-Prot for BRK1 Gene
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).