Free for academic non-profit institutions. Other users need a Commercial license

Aliases for BREA2 Gene

Subcategory (RNA class) for BREA2 Gene

ncRNA

Quality Score for this RNA gene is

2

Aliases for BREA2 Gene

  • Breast Cancer Estrogen-Induced Apoptosis 2 3
  • AC105219.1 5

External Ids for BREA2 Gene

Previous GeneCards Identifiers for BREA2 Gene

  • GC08P144852
  • GC08P144779

Summaries for BREA2 Gene

GeneCards Summary for BREA2 Gene

BREA2 (Breast Cancer Estrogen-Induced Apoptosis 2) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for BREA2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BREA2 Gene

Genomics for BREA2 Gene

GeneHancer (GH) Regulatory Elements for BREA2 Gene

Promoters and enhancers for BREA2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I143289 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 19.7 -405.5 -405469 3.4 PKNOX1 CLOCK SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 SLC30A9 POLR2B ENSG00000272172 ZNF696 SHARPIN MINCR BREA2 TOP1MT ZNF623 ZFP41 PARP10 GPAA1
GH08I144455 Enhancer 1.3 Ensembl ENCODE 19.6 +760.3 760292 1.6 HDGF HNRNPUL1 PKNOX1 FOXA2 ARNT ZFP64 SIN3A ZNF2 POLR2B ZNF766 ZNF251 ZNF623 ZNF7 LRRC14 ZNF250 ZNF16 CPSF1 VPS28 ZNF517 ZNF34
GH08I143683 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.7 -11.4 -11412 1.7 PKNOX1 ARID4B NEUROD1 SIN3A DMAP1 POLR2B E2F8 ZNF207 ZNF143 DEK ZNF707 CPSF1 VPS28 ZNF623 ADCK5 SLC52A2 PARP10 GPAA1 BREA2 ZC3H3
GH08I143820 Enhancer 1.2 Ensembl ENCODE dbSUPER 4.6 +127.2 127181 5.5 FOXA2 ARID4B ZNF48 ZSCAN9 RAD21 RARA ZNF121 SCRT2 THAP11 EGR2 PUF60 BREA2 SCRIB GC08M143801
GH08I143468 Enhancer 0.7 ENCODE dbSUPER 5.7 -225.1 -225132 4.3 RING1 KLF1 GLIS2 GLIS1 JRK ZNF696 ZNF623 CYHR1 CPSF1 VPS28 GSDMD ENSG00000254859 ZC3H3 LOC105375798
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BREA2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the BREA2 gene promoter:

Genomic Locations for BREA2 Gene

Genomic Locations for BREA2 Gene
chr8:143,696,154-143,698,413
(GRCh38/hg38)
Size:
2,260 bases
Orientation:
Plus strand
chr8:144,778,324-144,780,583
(GRCh37/hg19)

Genomic View for BREA2 Gene

Genes around BREA2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BREA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BREA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BREA2 Gene

Proteins for BREA2 Gene

Post-translational modifications for BREA2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for BREA2 Gene

Domains & Families for BREA2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BREA2 Gene

Function for BREA2 Gene

Phenotypes for BREA2 Gene

GenomeRNAi human phenotypes for BREA2:
genes like me logo Genes that share phenotypes with BREA2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BREA2 Gene

Localization for BREA2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BREA2 Gene

Pathways & Interactions for BREA2 Gene

SuperPathways for BREA2 Gene

No Data Available

Interacting Proteins for BREA2 Gene

Gene Ontology (GO) - Biological Process for BREA2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BREA2 Gene

Drugs & Compounds for BREA2 Gene

No Compound Related Data Available

Transcripts for BREA2 Gene

mRNA/cDNA for BREA2 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BREA2 Gene

Breast cancer estrogen-induced apoptosis 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BREA2 Gene

No ASD Table

Relevant External Links for BREA2 Gene

GeneLoc Exon Structure for
BREA2

Expression for BREA2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BREA2 Gene

mRNA differential expression in normal tissues according to GTEx for BREA2 Gene

This gene is overexpressed in Testis (x8.7).

SOURCE GeneReport for Unigene cluster for BREA2 Gene:

Hs.178095
genes like me logo Genes that share expression patterns with BREA2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BREA2 Gene

Orthologs for BREA2 Gene

Evolution for BREA2 Gene

ENSEMBL:
Gene Tree for BREA2 (if available)
TreeFam:
Gene Tree for BREA2 (if available)

No data available for Orthologs for BREA2 Gene

Paralogs for BREA2 Gene

No data available for Paralogs for BREA2 Gene

Variants for BREA2 Gene

Sequence variations from dbSNP and Humsavar for BREA2 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001760585 -- 143,698,638(+) G/A downstream_transcript_variant
rs1002041796 -- 143,697,425(+) G/A non_coding_transcript_variant
rs1004987274 -- 143,695,854(+) G/A upstream_transcript_variant
rs1005318098 -- 143,698,463(+) C/T downstream_transcript_variant
rs1005665695 -- 143,698,188(+) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for BREA2 Gene

Variant ID Type Subtype PubMed ID
nsv466007 CNV loss 19166990
nsv519816 CNV loss 19592680
nsv612893 CNV loss 21841781

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Additional Variant Information for BREA2 Gene

Disorders for BREA2 Gene

Additional Disease Information for BREA2

No disorders were found for BREA2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BREA2 Gene

Publications for BREA2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for BREA2 Gene

Sources for BREA2 Gene

Content
Loading form....