Aliases for BRD9 Gene
External Ids for BRD9 Gene
Previous GeneCards Identifiers for BRD9 Gene
GeneCards Summary for BRD9 Gene
BRD9 (Bromodomain Containing 9) is a Protein Coding gene. Diseases associated with BRD9 include Melkersson-Rosenthal Syndrome and Chronic Dacryoadenitis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and lysine-acetylated histone binding. An important paralog of this gene is BRD7.
UniProtKB/Swiss-Prot Summary for BRD9 Gene
Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).
Bromodomains (BRDs) are epigenetic reader domains that selectively recognize acetylated lysine residues on the tails of histone proteins, and are the only known protein modules that can target acetylated lysine residues.