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Aliases for BRD9 Gene
Aliases for BRD9 Gene
External Ids for BRD9 Gene
- HGNC: 25818
- Entrez Gene: 65980
- Ensembl: ENSG00000028310
- OMIM: 618465
- UniProtKB: Q9H8M2
Previous GeneCards Identifiers for BRD9 Gene
- GC05M000916
- GC05M000852
- GC05M000854
- GC05M000857
Summaries for BRD9 Gene
GeneCards Summary for BRD9 Gene
BRD9 (Bromodomain Containing 9) is a Protein Coding gene. Diseases associated with BRD9 include Melkersson-Rosenthal Syndrome and Chronic Dacryoadenitis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and lysine-acetylated histone binding. An important paralog of this gene is BRD7.
UniProtKB/Swiss-Prot Summary for BRD9 Gene
-
Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).
-
Bromodomains (BRDs) are epigenetic reader domains that selectively recognize acetylated lysine residues on the tails of histone proteins, and are the only known protein modules that can target acetylated lysine residues.
Additional gene information for BRD9 Gene
- HGNC(25818)
- Entrez Gene(65980)
- Ensembl(ENSG00000028310)
- OMIM(618465)
- UniProtKB(Q9H8M2)
- Open Targets Platform(ENSG00000028310)
- Search for BRD9 at DataMed
- Search for BRD9 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BRD9 Gene
Genomics for BRD9 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for BRD9 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around BRD9 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BRD9
- Top Transcription factor binding sites by QIAGEN in the BRD9 gene promoter:
-
- ATF6
- FOXO4
- GATA-1
- RORalpha2
- STAT3
Genomic Locations for BRD9 Gene
Genomic Locations for BRD9 Gene
- chr5:850,291-892,803
- (GRCh38/hg38)
- Size:
- 42,513 bases
- Orientation:
- Minus strand
- chr5:850,406-892,939
- (GRCh37/hg19)
- Size:
- 42,534 bases
- Orientation:
- Minus strand
Genomic View for BRD9 Gene
Genes around BRD9 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5p15.33 by HGNC
- 5p15.33 by Entrez Gene
- 5p15.33 by Ensembl
BRD9 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BRD9 Gene
Proteins for BRD9 Gene
-
Protein details for BRD9 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H8M2-BRD9_HUMAN
- Recommended name:
- Bromodomain-containing protein 9
- Protein Accession:
- Q9H8M2
- A6NFY8
- B4DMQ2
- B4DR93
- Q2XUS1
- Q6UWU9
- Q8IUS4
- Q9H5Q5
- Q9H7R9
Protein attributes for BRD9 Gene
- Size:
- 597 amino acids
- Molecular mass:
- 67000 Da
- Quaternary structure:
-
- Binds acetylated histones H3 and H4 (PubMed:22464331, PubMed:26365797). Binds butyrylated histone H4 (PubMed:26365797). Component of the multiprotein chromatin-remodeling subcomplex SWI/SNF called GBAF, which includes at least BICRA or BICRAL (mutually exclusive), BRD9, SS18, the core BAF subunits, SMARCA2/BRM, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, SMARCC1/BAF155, and SMARCD1/BAF60A (PubMed:29374058).
- SequenceCaution:
-
- Sequence=BAB15565.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
- Miscellaneous:
-
- [Isoform 5]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Three dimensional structures from OCA and Proteopedia for BRD9 Gene
Protein Expression for BRD9 Gene
Post-translational modifications for BRD9 Gene
Other Protein References for BRD9 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- GeneTex Anti-BRD9 antibody
- Creative Diagnostics Anti-BRD9 (aa 547-597) polyclonal antibody
- Creative Biolabs Mouse Anti-BRD9 Recombinant Antibody (1H8)
- Novus Biologicals Antibodies for BRD9
-
Abcam antibodies for BRD9
- Invitrogen Antibodies for BRD9 (AFLGC-BRD9)
- antibodies-online: Show 13 available BRD9 Antibodies ranked by validation data
-
Biorbyt antibodies for BRD9
-
Boster Bio Antibodies for BRD9
Protein Products
-
OriGene Purified Proteins for BRD9
- Search Origene for MassSpec and Protein Over-expression Lysates for BRD9
- Origene Custom Protein Services for BRD9
- antibodies-online: Search results for available BRD9 related products ranked by validation data
-
Signalway Proteins for BRD9
-
Abcam proteins for BRD9
No data available for DME Specific Peptides for BRD9 Gene
Domains & Families for BRD9 Gene
Gene Families for BRD9 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for BRD9 Gene
- InterPro:
- Blocks:
-
- Bromodomain signature
- ProtoNet:
Suggested Antigen Peptide Sequences for BRD9 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ58589, highly similar to Bromodomain-containing protein 9 (B4DMQ2_HUMAN)
- cDNA FLJ61450, highly similar to Bromodomain-containing protein 9 (B4DXI2_HUMAN)
- Rhabdomyosarcoma antigen MU-RMS-40.8 (BRD9_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9H8M2UniProtKB/Swiss-Prot:
BRD9_HUMAN :- The Bromo domain mediates interaction with histones that have acetylated lysine residues at specific positions (PubMed:22464331). Also recognizes and binds histones that are butyrylated (PubMed:26365797).
- Domain:
-
- The Bromo domain mediates interaction with histones that have acetylated lysine residues at specific positions (PubMed:22464331). Also recognizes and binds histones that are butyrylated (PubMed:26365797).
Function for BRD9 Gene
Molecular function for BRD9 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).
Phenotypes From GWAS Catalog for BRD9 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | NAS | 18559093 |
| GO:0005515 | protein binding | IEA,IPI | 25416956 |
| GO:0070577 | lysine-acetylated histone binding | IDA | 22464331 |
Phenotypes for BRD9 Gene
- MGI mutant phenotypes for BRD9:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for BRD9:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BRD9 - Select products 50% OFF >
- * BRD9 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for BRD9
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BRD9
-
Santa Cruz Biotechnology (SCBT) CRISPR for BRD9
miRNA for BRD9 Gene
- miRTarBase miRNAs that target BRD9
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BRD9
- Browse OriGene Inhibitory RNA Products For BRD9
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BRD9
Clone Products
- Applied Biological Materials (abm): Clones for BRD9 - Select products 50% OFF >
- * BRD9 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG204719
- MR204719
- MR204719L3
- MR204719L4
- RC208315
- RC208315L1
- RC208315L2
- RC208315L3
- RC208315L4
- RC229303
- RC229303L1
- RC229303L2
- RC229303L3
- RC229303L4
- RG208315
- RG229303
- RR215693
- RR215693L3
- RR215693L4
- MR204719L3V
- MR204719L4V
- RC208315L1V
- RC208315L2V
- RC208315L3V
- RC208315L4V
- RC229303L1V
- RC229303L2V
- RC229303L3V
- RC229303L4V
- RR215693L3V
- RR215693L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BRD9
- Addgene plasmids for BRD9
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BRD9
Cell Line Products
-
Horizon Cell Lines for BRD9
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BRD9 Gene
Localization for BRD9 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0016514 | SWI/SNF complex | IDA | 29374058 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for BRD9 Gene
Pathways & Interactions for BRD9 Gene
Interacting Proteins for BRD9 Gene
Selected Interacting proteins:
Q9H8M2-BRD9_HUMAN
ENSP00000419765
for BRD9 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for BRD9
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for BRD9 Gene
Transcripts for BRD9 Gene
mRNA/cDNA for BRD9 Gene
- 9 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 19 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000493082 750 nts (view in UCSC)
- ENST00000497410 1916 nts (view in UCSC)
- ENST00000483234 2211 nts (view in UCSC)
- ENST00000495794 4865 nts (view in UCSC)
- ENST00000490814 3477 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BRD9 - Select products 50% OFF >
- * BRD9 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for BRD9
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BRD9
-
Santa Cruz Biotechnology (SCBT) CRISPR for BRD9
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BRD9
- Browse OriGene Inhibitory RNA Products For BRD9
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BRD9
Clone Products
- Applied Biological Materials (abm): Clones for BRD9 - Select products 50% OFF >
- * BRD9 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG204719
- MR204719
- MR204719L3
- MR204719L4
- RC208315
- RC208315L1
- RC208315L2
- RC208315L3
- RC208315L4
- RC229303
- RC229303L1
- RC229303L2
- RC229303L3
- RC229303L4
- RG208315
- RG229303
- RR215693
- RR215693L3
- RR215693L4
- MR204719L3V
- MR204719L4V
- RC208315L1V
- RC208315L2V
- RC208315L3V
- RC208315L4V
- RC229303L1V
- RC229303L2V
- RC229303L3V
- RC229303L4V
- RR215693L3V
- RR215693L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BRD9
- Addgene plasmids for BRD9
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BRD9
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: |
| ExUns: | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | ^ | 22 | ^ | 23a | · | 23b | · | 23c | ^ | 24a | · | 24b | ^ | 25 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | |||||||||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||||||||||
| SP16: | |||||||||||||||||||||||||||||||||||||||
| SP17: | |||||||||||||||||||||||||||||||||||||||
| SP18: | |||||||||||||||||||||||||||||||||||||||
| SP19: | |||||||||||||||||||||||||||||||||||||||
| SP20: | |||||||||||||||||||||||||||||||||||||||
| SP21: |
Relevant External Links for BRD9 Gene
- GeneLoc Exon Structure for
- BRD9
Expression for BRD9 Gene
This gene is overexpressed in Bone marrow mesenchymal stem cell (57.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BRD9 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BRD9
SOURCE GeneReport for Unigene cluster for BRD9 Gene:
Hs.449278Evidence on tissue expression from TISSUES for BRD9 Gene
- Nervous system(4.6)
- Lung(4.5)
- Liver(4.3)
- Skin(2.2)
- Blood(2.2)
- Kidney(2.1)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for BRD9
-
OriGene qPCR primer pairs and template standards for BRD9
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BRD9 Gene
Orthologs for BRD9 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | BRD9 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | BRD9 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | BRD9 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | BRD9 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Brd9 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Brd9 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | BRD9 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | BRD9 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | BRD9 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | brd9 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | brd9 30 31 |
|
OneToOne | |
| zgc55797 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG7154 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | swsn-9 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for BRD9 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for BRD9 Gene
- ENSEMBL:
- Gene Tree for BRD9 (if available)
- TreeFam:
- Gene Tree for BRD9 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for BRD9: view image
Paralogs for BRD9 Gene
(2) SIMAP similar genes for BRD9 Gene using alignment to 8 proteins:
- BRD9_HUMAN
- B4DXI2_HUMAN
- C9JBY0_HUMAN
- F2Z2E8_HUMAN
- H0YAW8_HUMAN
- H0YBF1_HUMAN
- H0YBR9_HUMAN
- H0YBX9_HUMAN
Pseudogenes.org Pseudogenes for BRD9 Gene
Variants for BRD9 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BRD9 Gene
| SNP ID | Clinical significance and condition | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 708816 | Benign: not provided | 886,609(-) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 728823 | Likely Benign: not provided | 876,218(-) | G/A | INTRON_VARIANT | |
| 785112 | Benign: not provided | 865,587(-) | T/C | INTRON_VARIANT | |
| rs34292369 | -. - | p.Ala266Thrp.Ala170Thr | |||
| rs414349 | - | p.Ala389Thr |
Residual Variation Intolerance Score:
9.65% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.65;
56.82% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BRD9 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BRD9
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BRD9 Gene
Disorders for BRD9 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| melkersson-rosenthal syndrome |
|
|
| chronic dacryoadenitis |
|
|
| fissured tongue |
|
|
| rhabdoid cancer |
|
|
| nut midline carcinoma |
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Search BRD9 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for BRD9
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
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No data available for UniProtKB/Swiss-Prot and Genatlas for BRD9 Gene
Publications for BRD9 Gene
- A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications. (PMID: 26365797) Flynn EM … Cochran AG (Structure (London, England : 1993) 2015) 2 3 4
- Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. (PMID: 29374058) Alpsoy A … Dykhuizen EC (The Journal of biological chemistry 2018) 3 4
- Histone recognition and large-scale structural analysis of the human bromodomain family. (PMID: 22464331) Filippakopoulos P … Knapp S (Cell 2012) 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
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