Aliases for BPIFB1 Gene
External Ids for BPIFB1 Gene
Previous HGNC Symbols for BPIFB1 Gene
Previous GeneCards Identifiers for BPIFB1 Gene
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]
GeneCards Summary for BPIFB1 Gene
BPIFB1 (BPI Fold Containing Family B Member 1) is a Protein Coding gene. Diseases associated with BPIFB1 include Cholera and Papillary Cystadenocarcinoma. Among its related pathways are Innate Immune System and Defensins. Gene Ontology (GO) annotations related to this gene include lipid binding. An important paralog of this gene is BPIFB4.
UniProtKB/Swiss-Prot Summary for BPIFB1 Gene
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.