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Aliases for BPIFA4P Gene

Aliases for BPIFA4P Gene

  • BPI Fold Containing Family A Member 4, Pseudogene 2 3 5
  • PLUNC Family Pseudogene 2 3
  • BASE 3 4
  • Gene Expressed Only In The Salivary Gland And Breast Cancers 3
  • BPI Fold Containing Family A, Member 4, Pseudogene 4
  • Breast Cancer And Salivary Gland-Expressed Protein 4
  • Breast Cancer And Salivary Gland Expression Gene 2
  • Breast Cancer And Salivary Gland Expression 3
  • Putative Latherin 4
  • LATH 4

External Ids for BPIFA4P Gene

Previous GeneCards Identifiers for BPIFA4P Gene

  • GC20P031784

Summaries for BPIFA4P Gene

GeneCards Summary for BPIFA4P Gene

BPIFA4P (BPI Fold Containing Family A Member 4, Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for BPIFA4P Gene

  • Major protein in sweat, has surfactant properties.

Additional gene information for BPIFA4P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BPIFA4P Gene

Genomics for BPIFA4P Gene

GeneHancer (GH) Regulatory Elements for BPIFA4P Gene

Promoters and enhancers for BPIFA4P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I033206 Enhancer 0.2 FANTOM5 0.4 +12.9 12926 0.1 BPIFA1 BPIFB3 DNMT3B BPIFA4P ENSG00000224876
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BPIFA4P on UCSC Golden Path with GeneCards custom track

Genomic Locations for BPIFA4P Gene

Genomic Locations for BPIFA4P Gene
chr20:33,193,585-33,210,462
(GRCh38/hg38)
Size:
16,878 bases
Orientation:
Plus strand
chr20:31,781,391-31,798,268
(GRCh37/hg19)

Genomic View for BPIFA4P Gene

Genes around BPIFA4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BPIFA4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BPIFA4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BPIFA4P Gene

Proteins for BPIFA4P Gene

  • Protein details for BPIFA4P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86YQ2-LATH_HUMAN
    Recommended name:
    Putative BPIFA4P protein
    Protein Accession:
    Q86YQ2

    Protein attributes for BPIFA4P Gene

    Size:
    179 amino acids
    Molecular mass:
    19456 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BPIFA4P Gene

Post-translational modifications for BPIFA4P Gene

No Post-translational modifications

No data available for DME Specific Peptides for BPIFA4P Gene

Domains & Families for BPIFA4P Gene

Gene Families for BPIFA4P Gene

Protein Domains for BPIFA4P Gene

Suggested Antigen Peptide Sequences for BPIFA4P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86YQ2

UniProtKB/Swiss-Prot:

LATH_HUMAN :
  • Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
Family:
  • Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
genes like me logo Genes that share domains with BPIFA4P: view

Function for BPIFA4P Gene

Molecular function for BPIFA4P Gene

UniProtKB/Swiss-Prot Function:
Major protein in sweat, has surfactant properties.

Phenotypes From GWAS Catalog for BPIFA4P Gene

genes like me logo Genes that share phenotypes with BPIFA4P: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BPIFA4P Gene

Localization for BPIFA4P Gene

Subcellular locations from UniProtKB/Swiss-Prot for BPIFA4P Gene

Secreted.

No data available for Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BPIFA4P Gene

Pathways & Interactions for BPIFA4P Gene

SuperPathways for BPIFA4P Gene

No Data Available

Interacting Proteins for BPIFA4P Gene

Gene Ontology (GO) - Biological Process for BPIFA4P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BPIFA4P Gene

Drugs & Compounds for BPIFA4P Gene

No Compound Related Data Available

Transcripts for BPIFA4P Gene

mRNA/cDNA for BPIFA4P Gene

(1) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BPIFA4P Gene

BPI fold containing family A, member 4, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BPIFA4P Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1: - -
SP2: -
SP3: - - -
SP4:

Relevant External Links for BPIFA4P Gene

GeneLoc Exon Structure for
BPIFA4P
ECgene alternative splicing isoforms for
BPIFA4P

Expression for BPIFA4P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BPIFA4P Gene

mRNA differential expression in normal tissues according to GTEx for BPIFA4P Gene

This gene is overexpressed in Testis (x19.7) and Prostate (x18.6).

NURSA nuclear receptor signaling pathways regulating expression of BPIFA4P Gene:

BPIFA4P

SOURCE GeneReport for Unigene cluster for BPIFA4P Gene:

Hs.434194

mRNA Expression by UniProt/SwissProt for BPIFA4P Gene:

Q86YQ2-LATH_HUMAN
Tissue specificity: Expressed in breast cancer and salivary gland.
genes like me logo Genes that share expression patterns with BPIFA4P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BPIFA4P Gene

Orthologs for BPIFA4P Gene

Evolution for BPIFA4P Gene

ENSEMBL:
Gene Tree for BPIFA4P (if available)
TreeFam:
Gene Tree for BPIFA4P (if available)

No data available for Orthologs for BPIFA4P Gene

Paralogs for BPIFA4P Gene

No data available for Paralogs for BPIFA4P Gene

Variants for BPIFA4P Gene

Sequence variations from dbSNP and Humsavar for BPIFA4P Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000056520 -- 33,192,731(+) C/T upstream_transcript_variant
rs1000176217 -- 33,195,411(+) C/A intron_variant
rs1000226619 -- 33,193,200(+) C/G upstream_transcript_variant
rs1000235954 -- 33,202,860(+) A/G intron_variant
rs1000286931 -- 33,203,262(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for BPIFA4P Gene

Variant ID Type Subtype PubMed ID
esv2751912 CNV loss 17911159
nsv1056411 CNV loss 25217958
nsv1060241 CNV loss 25217958
nsv458964 CNV loss 19166990
nsv585926 CNV loss 21841781

Additional Variant Information for BPIFA4P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BPIFA4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BPIFA4P Gene

Disorders for BPIFA4P Gene

Additional Disease Information for BPIFA4P

No disorders were found for BPIFA4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BPIFA4P Gene

Publications for BPIFA4P Gene

  1. Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins. (PMID: 12538848) Egland KA … Pastan I (Proceedings of the National Academy of Sciences of the United States of America 2003) 2 3 4 58
  2. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. (PMID: 21787333) Bingle CD … Craven CJ (Biochemical Society transactions 2011) 2 3 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 58
  5. Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. (PMID: 24556642) Zeng Z … Shaffer JR (Caries research 2014) 3 58

Products for BPIFA4P Gene

Sources for BPIFA4P Gene

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