This locus represents naturally occurring read-through transcription between the neighboring C10orf32 (chromosome 10 open reading frame 32) and AS3MT (arsenic, +3 oxidation state, methyltransferase) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010] See more...

Aliases for BORCS7-ASMT Gene

Subcategory (RNA class) for BORCS7-ASMT Gene

lncRNA

Number of RNA Genes sources:

0 / 14

Aliases for BORCS7-ASMT Gene

  • BORCS7-ASMT Readthrough (NMD Candidate) 2 3 5 13
  • C10orf32-ASMT Readthrough (NMD Candidate) 2 3
  • C10orf32-AS3MT 3
  • C10orf32-ASMT 3

External Ids for BORCS7-ASMT Gene

Previous HGNC Symbols for BORCS7-ASMT Gene

  • C10orf32-ASMT

Summaries for BORCS7-ASMT Gene

Entrez Gene Summary for BORCS7-ASMT Gene

  • This locus represents naturally occurring read-through transcription between the neighboring C10orf32 (chromosome 10 open reading frame 32) and AS3MT (arsenic, +3 oxidation state, methyltransferase) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for BORCS7-ASMT Gene

BORCS7-ASMT (BORCS7-ASMT Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the lncRNA class. An important paralog of this gene is BORCS7.

Additional gene information for BORCS7-ASMT Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BORCS7-ASMT Gene

Genomics for BORCS7-ASMT Gene

GeneHancer (GH) Regulatory Elements for BORCS7-ASMT Gene

Promoters and enhancers for BORCS7-ASMT Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J102853 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +1.0 967 3.2 ZBTB40 ZNF217 EP300 ZSCAN5C TCF12 NRF1 ZNF300 POLR2G USF1 NCOR1 BORCS7 BORCS7-ASMT ENSG00000282772 AS3MT NOLC1 TAF5 PDCD11 GBF1 WBP1L L13705-002
GH10J102868 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +15.6 15591 2 POLR2G KDM6A ZBTB26 ZBTB7A ZNF341 ZSCAN9 POLR2A KMT2B KLF9 ZBTB17 AS3MT ENSG00000283337 WBP1L L13713-033 BORCS7-ASMT
GH10J102876 Promoter 0.9 EPDnew 0.4 +22.7 22732 0.1 TEAD1 FOXA2 CREM FOXP1 BCL6 HHEX RXRA KAT2B HNF4A ARID3A AS3MT L13713-033 BORCS7-ASMT
GH10J102864 Enhancer 0.3 Ensembl 0.4 +10.0 9991 0.4 NR2F2 CBFA2T3 L13705-002 AS3MT ENSG00000283337 BORCS7 BORCS7-ASMT
GH10J102901 Enhancer 0.6 ENCODE 0.3 +47.4 47369 0.2 CTCF REST RAD21 TRIM22 SMC3 ZNF384 ELF1 ZNF654 MAFF MAFK ENSG00000272912 RPL22P17 ENSG00000286575 AS3MT BORCS7-ASMT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BORCS7-ASMT on UCSC Golden Path with GeneCards custom track

Genomic Locations for BORCS7-ASMT Gene

Genomic Locations for BORCS7-ASMT Gene
chr10:102,854,210-102,901,899
(GRCh38/hg38)
Size:
47,690 bases
Orientation:
Plus strand
chr10:104,613,967-104,661,656
(GRCh37/hg19)
Size:
47,690 bases
Orientation:
Plus strand

Genomic View for BORCS7-ASMT Gene

Genes around BORCS7-ASMT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BORCS7-ASMT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BORCS7-ASMT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BORCS7-ASMT Gene

Proteins for BORCS7-ASMT Gene

  • Protein details for BORCS7-ASMT Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1R7-A0A0B4J1R7_HUMAN
    Recommended name:
    BORCS7-ASMT readthrough (NMD candidate)
    Protein Accession:
    A0A0B4J1R7

    Protein attributes for BORCS7-ASMT Gene

    Size:
    106 amino acids
    Molecular mass:
    11695 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BORCS7-ASMT Gene

Post-translational modifications for BORCS7-ASMT Gene

No Post-translational modifications

Other Protein References for BORCS7-ASMT Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for BORCS7-ASMT Gene

Domains & Families for BORCS7-ASMT Gene

Protein Domains for BORCS7-ASMT Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with BORCS7-ASMT: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for BORCS7-ASMT Gene

Function for BORCS7-ASMT Gene

Phenotypes From GWAS Catalog for BORCS7-ASMT Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BORCS7-ASMT Gene

Localization for BORCS7-ASMT Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BORCS7-ASMT Gene

Pathways & Interactions for BORCS7-ASMT Gene

PathCards logo

SuperPathways for BORCS7-ASMT Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for BORCS7-ASMT Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for BORCS7-ASMT Gene

Drugs & Compounds for BORCS7-ASMT Gene

No Compound Related Data Available

Transcripts for BORCS7-ASMT Gene

mRNA/cDNA for BORCS7-ASMT Gene

1 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BORCS7-ASMT Gene

No ASD Table

Relevant External Links for BORCS7-ASMT Gene

GeneLoc Exon Structure for
BORCS7-ASMT

Expression for BORCS7-ASMT Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BORCS7-ASMT Gene

Orthologs for BORCS7-ASMT Gene

This gene was present in the common ancestor of chordates.

Orthologs for BORCS7-ASMT Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10ORF32 31
  • 100 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 2010012O05Rik 31
  • 96 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 31
  • 96 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 90 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 88 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 31
  • 82 (a)
OneToMany
chicken
(Gallus gallus)
Aves C6H10ORF32 31
  • 83 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 83 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii C13H10orf32 31
  • 79 (a)
OneToMany
Species where no ortholog for BORCS7-ASMT was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BORCS7-ASMT Gene

ENSEMBL:
Gene Tree for BORCS7-ASMT (if available)
TreeFam:
Gene Tree for BORCS7-ASMT (if available)

Paralogs for BORCS7-ASMT Gene

Paralogs for BORCS7-ASMT Gene

genes like me logo Genes that share paralogs with BORCS7-ASMT: view

Variants for BORCS7-ASMT Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BORCS7-ASMT Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
768385 Benign: not provided 102,870,074(+) G/T INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for BORCS7-ASMT Gene

Structural Variations from Database of Genomic Variants (DGV) for BORCS7-ASMT Gene

Variant ID Type Subtype PubMed ID
esv1651901 CNV deletion 17803354
esv2489056 CNV deletion 19546169
esv2740239 CNV deletion 23290073
esv2740251 CNV deletion 23290073
esv3546767 CNV deletion 23714750
esv3624404 CNV loss 21293372
nsv1069070 CNV deletion 25765185
nsv1147211 CNV deletion 26484159
nsv948172 CNV duplication 23825009

Variation tolerance for BORCS7-ASMT Gene

Gene Damage Index Score: 0.07; 1.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for BORCS7-ASMT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BORCS7-ASMT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BORCS7-ASMT Gene

Disorders for BORCS7-ASMT Gene

Additional Disease Information for BORCS7-ASMT

No disorders were found for BORCS7-ASMT Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BORCS7-ASMT Gene

Publications for BORCS7-ASMT Gene

  1. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. (PMID: 25249183) Lu X … Gu D (Human molecular genetics 2015) 3 54
  2. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 54
  3. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. (PMID: 24954895) Simino J … Rao DC (American journal of human genetics 2014) 3 54
  4. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S … Sullivan PF (Nature genetics 2013) 3 54
  5. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 54

Products for BORCS7-ASMT Gene

Sources for BORCS7-ASMT Gene