Free for academic non-profit institutions. Other users need a Commercial license

Aliases for BORCS7-ASMT Gene

Subcategory (RNA class) for BORCS7-ASMT Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for BORCS7-ASMT Gene

  • BORCS7-ASMT Readthrough (NMD Candidate) 2 3 5
  • C10orf32-ASMT Readthrough (NMD Candidate) 2 3
  • C10orf32-AS3MT 3
  • C10orf32-ASMT 3

External Ids for BORCS7-ASMT Gene

Previous HGNC Symbols for BORCS7-ASMT Gene

  • C10orf32-ASMT

Summaries for BORCS7-ASMT Gene

Entrez Gene Summary for BORCS7-ASMT Gene

  • This locus represents naturally occurring read-through transcription between the neighboring C10orf32 (chromosome 10 open reading frame 32) and AS3MT (arsenic, +3 oxidation state, methyltransferase) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for BORCS7-ASMT Gene

BORCS7-ASMT (BORCS7-ASMT Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is BORCS7.

Additional gene information for BORCS7-ASMT Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BORCS7-ASMT Gene

Genomics for BORCS7-ASMT Gene

GeneHancer (GH) Regulatory Elements for BORCS7-ASMT Gene

Promoters and enhancers for BORCS7-ASMT Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I102853 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +0.2 244 1.5 HDGF FOXA2 SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 BORCS7 ENSG00000282772 BORCS7-ASMT GBF1 NOLC1 PDCD11 RPEL1 TAF5 SFXN2 WBP1L
GH10I102855 Enhancer 1 ENCODE 550.8 +1.8 1809 1.5 FOXA2 FEZF1 GLI4 ZNF2 ZNF48 GLIS2 ZNF213 KLF7 FOS SP3 BORCS7 ENSG00000282772 BORCS7-ASMT AS3MT TAF5 PDCD11 GC10P102871
GH10I102850 Enhancer 0.9 ENCODE 0.8 -4.0 -4031 0.2 FOXA2 MLX ARID4B DMAP1 ETS1 YY1 ATF7 RXRA MXD4 MIER2 BORCS7 BORCS7-ASMT PTGES3P4 ENSG00000282772
GH10I102868 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 0.4 +15.5 15464 1.6 MLX DMAP1 ZNF48 ZNF335 THAP11 PAF1 SP3 SP5 ELF1 ETV4 AS3MT GC10P102871 ENSG00000283337 BORCS7-ASMT GC10M102888
GH10I102858 Enhancer 0.2 FANTOM5 0.8 +4.7 4692 0.4 AS3MT BORCS7 BORCS7-ASMT ENSG00000282772 GC10P102871
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BORCS7-ASMT on UCSC Golden Path with GeneCards custom track

Genomic Locations for BORCS7-ASMT Gene

Genomic Locations for BORCS7-ASMT Gene
chr10:102,854,210-102,901,899
(GRCh38/hg38)
Size:
47,690 bases
Orientation:
Plus strand
chr10:104,613,967-104,661,656
(GRCh37/hg19)

Genomic View for BORCS7-ASMT Gene

Genes around BORCS7-ASMT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BORCS7-ASMT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BORCS7-ASMT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BORCS7-ASMT Gene

Proteins for BORCS7-ASMT Gene

  • Protein details for BORCS7-ASMT Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1R7
    Recommended name:
    BORCS7-ASMT readthrough (NMD candidate)
    Protein Accession:
    A0A0B4J1R7

    Protein attributes for BORCS7-ASMT Gene

    Size:
    106 amino acids
    Molecular mass:
    11695 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BORCS7-ASMT Gene

Post-translational modifications for BORCS7-ASMT Gene

No Post-translational modifications

Other Protein References for BORCS7-ASMT Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for BORCS7-ASMT Gene

Domains & Families for BORCS7-ASMT Gene

Protein Domains for BORCS7-ASMT Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BORCS7-ASMT: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BORCS7-ASMT Gene

Function for BORCS7-ASMT Gene

Phenotypes From GWAS Catalog for BORCS7-ASMT Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BORCS7-ASMT Gene

Localization for BORCS7-ASMT Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BORCS7-ASMT Gene

Pathways & Interactions for BORCS7-ASMT Gene

SuperPathways for BORCS7-ASMT Gene

No Data Available

Interacting Proteins for BORCS7-ASMT Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000299353%0d%0a9606.ENSP00000282030%0d%0a9606.ENSP00000323795%0d%0a9606.ENSP00000373669%0d%0a
Selected Interacting proteins: ENSP00000299353 for BORCS7-ASMT Gene via STRING

Gene Ontology (GO) - Biological Process for BORCS7-ASMT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BORCS7-ASMT Gene

Drugs & Compounds for BORCS7-ASMT Gene

No Compound Related Data Available

Transcripts for BORCS7-ASMT Gene

mRNA/cDNA for BORCS7-ASMT Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BORCS7-ASMT Gene

No ASD Table

Relevant External Links for BORCS7-ASMT Gene

GeneLoc Exon Structure for
BORCS7-ASMT
ECgene alternative splicing isoforms for
BORCS7-ASMT

Expression for BORCS7-ASMT Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BORCS7-ASMT Gene

Orthologs for BORCS7-ASMT Gene

This gene was present in the common ancestor of chordates.

Orthologs for BORCS7-ASMT Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10ORF32 34
  • 100 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 96 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 2010012O05Rik 34
  • 96 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 90 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 88 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 82 (a)
OneToMany
chicken
(Gallus gallus)
Aves C6H10ORF32 34
  • 83 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 83 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii C13H10orf32 34
  • 79 (a)
OneToMany
Species where no ortholog for BORCS7-ASMT was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BORCS7-ASMT Gene

ENSEMBL:
Gene Tree for BORCS7-ASMT (if available)
TreeFam:
Gene Tree for BORCS7-ASMT (if available)

Paralogs for BORCS7-ASMT Gene

Paralogs for BORCS7-ASMT Gene

genes like me logo Genes that share paralogs with BORCS7-ASMT: view

Variants for BORCS7-ASMT Gene

Sequence variations from dbSNP and Humsavar for BORCS7-ASMT Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000054821 -- 102,888,219(+) C/T intron_variant
rs1000061166 -- 102,867,005(+) C/T intron_variant
rs1000134191 -- 102,901,490(+) G/C non_coding_transcript_variant
rs1000168209 -- 102,898,160(+) A/C intron_variant
rs1000216360 -- 102,894,524(+) A/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for BORCS7-ASMT Gene

Variant ID Type Subtype PubMed ID
esv1651901 CNV deletion 17803354
esv2489056 CNV deletion 19546169
esv2740239 CNV deletion 23290073
esv2740251 CNV deletion 23290073
esv3546767 CNV deletion 23714750
esv3624404 CNV loss 21293372
nsv1069070 CNV deletion 25765185
nsv1147211 CNV deletion 26484159
nsv948172 CNV duplication 23825009

Variation tolerance for BORCS7-ASMT Gene

Gene Damage Index Score: 0.07; 1.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for BORCS7-ASMT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BORCS7-ASMT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BORCS7-ASMT Gene

Disorders for BORCS7-ASMT Gene

No disorders were found for BORCS7-ASMT Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BORCS7-ASMT Gene

Publications for BORCS7-ASMT Gene

  1. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. (PMID: 25249183) Lu X … Gu D (Human molecular genetics 2015) 3 58
  2. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 58
  3. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. (PMID: 24954895) Simino J … Rao DC (American journal of human genetics 2014) 3 58
  4. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 58
  5. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S … Sullivan PF (Nature genetics 2013) 3 58

Products for BORCS7-ASMT Gene

Sources for BORCS7-ASMT Gene

Content
Loading form....