Aliases for BOLL Gene
External Ids for BOLL Gene
Previous GeneCards Identifiers for BOLL Gene
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BOLL Gene
BOLL (Boule Homolog, RNA Binding Protein) is a Protein Coding gene. Diseases associated with BOLL include Azoospermia and Male Infertility. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is DAZ2.
UniProtKB/Swiss-Prot for BOLL Gene
Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3-UTR of mRNAs and regulating their translation (By similarity).