Aliases for BOLA2B Gene
External Ids for BOLA2B Gene
Previous GeneCards Identifiers for BOLA2B Gene
This gene is located within a region of a segmental duplication on chromosome 16 and is identical to BOLA2 (bolA family member 2). The product of this gene belongs to a family of proteins that are widely conserved and may be involved in iron maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for BOLA2B Gene
BOLA2B (BolA Family Member 2B) is a Protein Coding gene. Diseases associated with BOLA2B include Multiple Mitochondrial Dysfunctions Syndrome 2 With Hyperglycinemia and Multiple Mitochondrial Dysfunctions Syndrome. An important paralog of this gene is BOLA2.
UniProtKB/Swiss-Prot Summary for BOLA2B Gene
Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts together with the monothiol glutaredoxin GLRX3 (PubMed:26613676, PubMed:27519415).