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BOLA2-SMG1P6 Gene(Protein Coding)

BOLA2-SMG1P6 Readthrough

GCID:
GC16M029444
GIFtS:
14
Genes Participants
UDN Logo

Aliases for BOLA2-SMG1P6 Gene

Aliases for BOLA2-SMG1P6 Gene

  • BOLA2-SMG1P6 Readthrough 2 3 5
  • BOLA2-SMG1P6 Readthrough Protein 3
  • BOLA2-SMG1P6 Protein 3

External Ids for BOLA2-SMG1P6 Gene

Previous GeneCards Identifiers for BOLA2-SMG1P6 Gene

  • GC16U902267

Summaries for BOLA2-SMG1P6 Gene

Entrez Gene Summary for BOLA2-SMG1P6 Gene

  • This gene represents naturally-occurring readthrough transcription between the upstream BOLA2 (bolA family member 2) and downstream SMG1 pseudogene 6 (SMG1P6) loci. Alternative splicing results in multiple transcript variants, some of which may encode proteins with an N-terminus similar to BOLA2 and a C-terminus related to SMG1 phosphatidylinositol 3-kinase-related kinase. [provided by RefSeq, Feb 2016]

GeneCards Summary for BOLA2-SMG1P6 Gene

BOLA2-SMG1P6 (BOLA2-SMG1P6 Readthrough) is a Protein Coding gene.

Additional gene information for BOLA2-SMG1P6 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOLA2-SMG1P6 Gene

Genomics for BOLA2-SMG1P6 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for BOLA2-SMG1P6 Gene

Promoters and enhancers for BOLA2-SMG1P6 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH16J029453 Promoter/Enhancer 1.2 EPDnew Ensembl dbSUPER 650.7 +0.1 50 2 BOLA2 BOLA2-SMG1P6 SLX1B SLX1B-SULT1A4 GC16P029442
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BOLA2-SMG1P6 on UCSC Golden Path with GeneCards custom track

Genomic Locations for BOLA2-SMG1P6 Gene

Genomic Locations for BOLA2-SMG1P6 Gene
chr16:29,443,230-29,454,651
(GRCh38/hg38)
Size:
11,422 bases
Orientation:
Minus strand
chr16:29,454,551-29,465,972
(GRCh37/hg19)
Size:
11,422 bases
Orientation:
Minus strand

Genomic View for BOLA2-SMG1P6 Gene

Genes around BOLA2-SMG1P6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BOLA2-SMG1P6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BOLA2-SMG1P6 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for BOLA2-SMG1P6 Gene

Proteins for BOLA2-SMG1P6 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for BOLA2-SMG1P6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J295-A0A0B4J295_HUMAN
    Recommended name:
    BOLA2-SMG1P6 readthrough
    Protein Accession:
    A0A0B4J295

    Protein attributes for BOLA2-SMG1P6 Gene

    Size:
    124 amino acids
    Molecular mass:
    13658 Da
    Quaternary structure:
    No Data Available

  • Protein details for BOLA2-SMG1P6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BTW0-H3BTW0_HUMAN
    Recommended name:
    BOLA2-SMG1P6 readthrough
    Protein Accession:
    H3BTW0

    Protein attributes for BOLA2-SMG1P6 Gene

    Size:
    89 amino acids
    Molecular mass:
    9854 Da
    Quaternary structure:
    No Data Available

  • Protein details for BOLA2-SMG1P6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BVE0-H3BVE0_HUMAN
    Recommended name:
    BOLA2-SMG1P6 readthrough
    Protein Accession:
    H3BVE0

    Protein attributes for BOLA2-SMG1P6 Gene

    Size:
    249 amino acids
    Molecular mass:
    27665 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BOLA2-SMG1P6 Gene

Post-translational modifications for BOLA2-SMG1P6 Gene

No Post-translational modifications

Other Protein References for BOLA2-SMG1P6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BOLA2-SMG1P6 Gene

Domains & Families for BOLA2-SMG1P6 Gene

Gene Families for BOLA2-SMG1P6 Gene

Unknown:
  • Belongs to the BolA/IbaG family.
  • Belongs to the BolA/IbaG family.

Protein Domains for BOLA2-SMG1P6 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BOLA2-SMG1P6: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BOLA2-SMG1P6 Gene

Function for BOLA2-SMG1P6 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BOLA2-SMG1P6 Gene

Localization for BOLA2-SMG1P6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BOLA2-SMG1P6 Gene

Pathways & Interactions for BOLA2-SMG1P6 Gene

SuperPathways for BOLA2-SMG1P6 Gene

PathCards logo More details on SuperPathways for BOLA2-SMG1P6
No Data Available

Interacting Proteins for BOLA2-SMG1P6 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000458075%0d%0a9606.ENSP00000380313%0d%0a9606.ENSP00000307272%0d%0a9606.ENSP00000265960%0d%0a9606.ENSP00000349959%0d%0a9606.ENSP00000344789%0d%0a
Selected Interacting proteins: ENSP00000458075 for BOLA2-SMG1P6 Gene via STRING

GPS-Prot Interaction Network for BOLA2-SMG1P6

Gene Ontology (GO) - Biological Process for BOLA2-SMG1P6 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BOLA2-SMG1P6 Gene

Drugs & Compounds for BOLA2-SMG1P6 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for BOLA2-SMG1P6 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for BOLA2-SMG1P6 Gene

(6) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BOLA2-SMG1P6 Gene

No ASD Table

Relevant External Links for BOLA2-SMG1P6 Gene

GeneLoc Exon Structure for
BOLA2-SMG1P6
ECgene alternative splicing isoforms for
BOLA2-SMG1P6

Expression for BOLA2-SMG1P6 Gene

Products:

  1. Primer
  2. Gene Expression Assay

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BOLA2-SMG1P6 Gene

Orthologs for BOLA2-SMG1P6 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA2-SMG1P6 Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 34
OneToOne
zebrafish
(Danio rerio)
 Actinopterygii smg1 34
  • 3 (a)
 OneToMany
fruit fly
(Drosophila melanogaster)
 Insecta nonC 34
  • 1 (a)
 OneToMany
worm
(Caenorhabditis elegans)
 Secernentea smg-1 34
  • 1 (a)
 OneToMany
baker's yeast
(Saccharomyces cerevisiae)
 Saccharomycetes TOR2 34
  • 1 (a)
 OneToMany
Species where no ortholog for BOLA2-SMG1P6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for BOLA2-SMG1P6 Gene

ENSEMBL:
Gene Tree for BOLA2-SMG1P6 (if available)
TreeFam:
Gene Tree for BOLA2-SMG1P6 (if available)

Paralogs for BOLA2-SMG1P6 Gene

Pseudogenes.org Pseudogenes for BOLA2-SMG1P6 Gene

genes like me logo Genes that share paralogs with BOLA2-SMG1P6: view

No data available for Paralogs for BOLA2-SMG1P6 Gene

Variants for BOLA2-SMG1P6 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for BOLA2-SMG1P6 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1002602928 -- 29,455,497(-) C/T upstream_transcript_variant
rs1008372191 -- 29,446,746(-) G/A intron_variant
rs1008405178 -- 29,449,167(-) A/G intron_variant
rs1009879525 -- 29,449,556(-) G/A intron_variant
rs1010324592 -- 29,452,474(-) T/C intron_variant

Additional Variant Information for BOLA2-SMG1P6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BOLA2-SMG1P6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for BOLA2-SMG1P6 Gene

Disorders for BOLA2-SMG1P6 Gene

Additional Disease Information for BOLA2-SMG1P6

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for BOLA2-SMG1P6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BOLA2-SMG1P6 Gene

Publications for BOLA2-SMG1P6 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 58

Products for BOLA2-SMG1P6 Gene

Sources for BOLA2-SMG1P6 Gene

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