Aliases for BNIP3L Gene
Aliases for BNIP3L Gene
External Ids for BNIP3L Gene
- HGNC: 1085
- Entrez Gene: 665
- Ensembl: ENSG00000104765
- OMIM: 605368
- UniProtKB: O60238
Previous GeneCards Identifiers for BNIP3L Gene
- GC08P026013
- GC08P026594
- GC08P026262
- GC08P024785
- GC08P026240
Summaries for BNIP3L Gene
-
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
GeneCards Summary for BNIP3L Gene
BNIP3L (BCL2 Interacting Protein 3 Like) is a Protein Coding gene. Diseases associated with BNIP3L include Glossopharyngeal Neuralgia. Among its related pathways are Mitophagy - animal and Gene Expression. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is BNIP3.
UniProtKB/Swiss-Prot for BNIP3L Gene
-
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Additional gene information for BNIP3L Gene
- Monarch Initiative
- Search for BNIP3L at DataMed
- Search for BNIP3L at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BNIP3L Gene
Genomics for BNIP3L Gene
GeneHancer (GH) Regulatory Elements for BNIP3L Gene
Promoters and enhancers for BNIP3L Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around BNIP3L on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the BNIP3L gene promoter:
Regulatory Element Products
Genomic Locations for BNIP3L Gene
Genomic Locations for BNIP3L Gene
- chr8:26,382,898-26,505,636
- (GRCh38/hg38)
- Size:
- 122,739 bases
- Orientation:
- Plus strand
- chr8:26,240,414-26,363,152
- (GRCh37/hg19)
Genomic View for BNIP3L Gene
Genes around BNIP3L on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.2 by Ensembl
- 8p21.2 by Entrez Gene
- 8p21.2 by HGNC
BNIP3L Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BNIP3L Gene
Proteins for BNIP3L Gene
-
Protein details for BNIP3L Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60238-BNI3L_HUMAN
- Recommended name:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
- Protein Accession:
- O60238
- B0AZS9
- Q5JW63
- Q8NF87
Protein attributes for BNIP3L Gene
- Size:
- 219 amino acids
- Molecular mass:
- 23930 Da
- Quaternary structure:
-
- Self-associates. Interacts with BNIP3 and STEAP3. Interacts with human adenovirus-2 E1B 19 kDa protein. Interacts (via BH3 domain) with SPATA18 (via coiled-coil domains).
- SequenceCaution:
-
- Sequence=CAI46217.1; Type=Erroneous termination; Positions=122; Note=Translated as Glu.; Evidence={ECO:0000305};
Protein Expression for BNIP3L Gene
Post-translational modifications for BNIP3L Gene
- Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
- Ubiquitination at posLast=154154
- Modification sites at PhosphoSitePlus
Other Protein References for BNIP3L Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Quality Products:
No data available for DME Specific Peptides for BNIP3L Gene
Domains & Families for BNIP3L Gene
Gene Families for BNIP3L Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted membrane proteins
- Transporters
Suggested Antigen Peptide Sequences for BNIP3L Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O60238- Family:
-
- Belongs to the NIP3 family.
Function for BNIP3L Gene
Molecular function for BNIP3L Gene
- GENATLAS Biochemistry:
- BCL2/adenovirus E1B,interacting 3-like,proapoptotic,inhibiting growth of cancer cells,widely expressed (see TSG8A) and expressed in target of the mitochondria,when inducing apoptosis
- UniProtKB/Swiss-Prot Function:
- Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Phenotypes From GWAS Catalog for BNIP3L Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 9973195 |
| GO:0005521 | lamin binding | IPI | 10381623 |
| GO:0042802 | identical protein binding | IPI | 10381623 |
| GO:0042803 | protein homodimerization activity | IDA | 10381623 |
| GO:0046982 | protein heterodimerization activity | IDA | 10381623 |
Phenotypes for BNIP3L Gene
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miRNA for BNIP3L Gene
- miRTarBase miRNAs that target BNIP3L
-
- hsa-mir-221-3p (MIRT003359)
- hsa-let-7b-5p (MIRT052099)
- hsa-let-7a-5p (MIRT052472)
- hsa-mir-137 (MIRT054568)
- hsa-mir-30d-5p (MIRT438872)
- hsa-mir-6781-3p (MIRT660165)
- hsa-mir-2682-3p (MIRT660166)
- hsa-mir-4778-3p (MIRT660167)
- hsa-mir-877-3p (MIRT660168)
- hsa-mir-6877-3p (MIRT660169)
- hsa-mir-7109-3p (MIRT660170)
- hsa-mir-6819-3p (MIRT660171)
- hsa-mir-30a-5p (MIRT734912)
miRNA Products
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Cell Line Products
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BNIP3L Gene
Localization for BNIP3L Gene
Subcellular locations from UniProtKB/Swiss-Prot for BNIP3L Gene
- Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein. Note=Colocalizes with SPATA18 at the mitochondrion outer membrane.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 5 |
| endoplasmic reticulum | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| peroxisome | 1 |
| lysosome | 1 |
- Mitochondria (4)
- Nuclear speckles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005635 | nuclear envelope | IEA,IDA | 10381623 |
| GO:0005739 | mitochondrion | IEA,IDA | 9973195 |
| GO:0005740 | mitochondrial envelope | IEA | -- |
| GO:0005741 | mitochondrial outer membrane | TAS | -- |
Pathways & Interactions for BNIP3L Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | TP53 Regulates Transcription of Cell Death Genes | ||
| 3 | Mitophagy - animal | ||
| 4 | Apoptosis and Autophagy | ||
| 5 | Autophagy Pathway | ||
Pathways by source for BNIP3L Gene
3 BioSystems pathways for BNIP3L Gene
5 Reactome pathways for BNIP3L Gene
1 KEGG pathway for BNIP3L Gene
1 R&D Systems pathway for BNIP3L Gene
1 Cell Signaling Technology pathway for BNIP3L Gene
Interacting Proteins for BNIP3L Gene
Selected Interacting proteins:
O60238-BNI3L_HUMAN
ENSP00000370003
for BNIP3L Gene via
UniProtKB
IID
MINT
STRING
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0010917 | negative regulation of mitochondrial membrane potential | IEA | -- |
| GO:0016032 | viral process | IEA | -- |
| GO:0016239 | positive regulation of macroautophagy | IGI | 19273585 |
| GO:0035694 | mitochondrial protein catabolic process | IMP | 21264228 |
No data available for SIGNOR curated interactions for BNIP3L Gene
Transcripts for BNIP3L Gene
mRNA/cDNA for BNIP3L Gene
- (3) REFSEQ mRNAs :
- (19) Additional mRNA sequences :
- (770) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BNIP3L Gene
CRISPR Products
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OriGene CRISPR knockouts for BNIP3L
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Vectors and viruses for KO, Activation, Repression, and more
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miRNA Products
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Inhibitory RNA Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for BNIP3L
- genomics-online: cdna clones - Search results for available BNIP3L gene related products
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for BNIP3L Gene
This gene is overexpressed in Adrenal (27.6) and Nasal epithelium (25.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BNIP3L Gene
NURSA nuclear receptor signaling pathways regulating expression of BNIP3L Gene:
BNIP3LSOURCE GeneReport for Unigene cluster for BNIP3L Gene:
Hs.131226Evidence on tissue expression from TISSUES for BNIP3L Gene
- Nervous system(5)
- Blood(4.6)
- Bone marrow(4.4)
- Kidney(4.4)
- Liver(4.4)
- Skin(4.3)
- Heart(2.4)
- Lung(2.3)
- Muscle(2.3)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for BNIP3L
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OriGene qPCR primer pairs for BNIP3L
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Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BNIP3L Gene
Orthologs for BNIP3L Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BNIP3L 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
| BNIP3L 33 |
|
||||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | BNIP3L 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Bnip3l 33 34 |
|
||
| Bnip3l-ps 16 |
|
|
|||
| rat (Rattus norvegicus) |
Mammalia | Bnip3l 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | BNIP3L 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | BNIP3L 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | BNIP3L 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | BNIP3L 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | bnip3l 33 |
|
||
| Str.1479 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.19770 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | bnip3la 33 34 |
|
||
| bnip3lb 34 |
|
OneToMany | |||
| wufb52b03 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1851 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3722 34 |
|
OneToMany |
- Species where no ortholog for BNIP3L was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for BNIP3L Gene
(1) SIMAP similar genes for BNIP3L Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for BNIP3L Gene
Variants for BNIP3L Gene
| SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000014681 | -- | 26,412,582(+) | A/T | 3_prime_UTR_variant | |
| rs1000074983 | -- | 26,383,626(+) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000174677 | -- | 26,393,021(+) | T/C | intron_variant | |
| rs1000190166 | -- | 26,389,358(+) | T/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000368597 | -- | 26,381,651(+) | T/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3572648 | CNV | loss | 25503493 |
| esv3616666 | OTHER | inversion | 21293372 |
| nsv824580 | CNV | gain | 20364138 |
| nsv831273 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
29.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.49;
10.65% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BNIP3L Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BNIP3L
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BNIP3L Gene
Disorders for BNIP3L Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glossopharyngeal neuralgia |
|
|
Search BNIP3L in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for BNIP3L
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for BNIP3L Gene
Publications for BNIP3L Gene
- Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. (PMID: 9523198) Matsushima M … Nakamura Y (Genes, chromosomes & cancer 1998) 2 3 4 22 58
- The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation. (PMID: 12663450) Aerbajinai W … Miller JL (Blood 2003) 3 4 22 58
- Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. (PMID: 9867803) Chen G … Greenberg A (The Journal of biological chemistry 1999) 3 4 22 58
- Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. (PMID: 21264228) Kitamura N … Arakawa H (PloS one 2011) 3 4 58
- MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer. (PMID: 20819778) Zhang X … Wu X (Carcinogenesis 2010) 3 44 58
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
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- Addgene plasmids for BNIP3L
- antibodies-online: Search results for 113 available BNIP3L Antibodies ranked by validation data
- Compare Top BNIP3L Antibodies
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- antibodies-online: Search results for 1 available BNIP3L Elisa Kits ranked by validation data
- Compare Top BNIP3L Elisa Kits
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- antibodies-online: Search results for 4 available BNIP3L Proteins ranked by validation data
- Compare Top BNIP3L Proteins
- Quality Products:
- GeneTex BNIP3L antibody for BNIP3L
- Search GeneTex for Proteins for BNIP3L
- ViGene Biosciences adenoviral particle packaged cDNA for BNIP3L gene
- ViGene Biosciences lentiviral particle packaged cDNA for BNIP3L gene
- ViGene Biosciences ready-to-package AAV shRNAs for BNIP3L gene
- Search ViGene Biosciences for BNIP3L
- Search Santa Cruz Biotechnology (SCBT) for BNIP3L siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for BNIP3L
- Custom Antibody ServicesProSci Antibodies for BNIP3L
- Search for BNIP3L Proteins at ProSci
- Horizon Cell Lines for BNIP3L
- genomics-online: cdna clones - Search results for available BNIP3L gene related products
- orf clones - Search results for available BNIP3L gene related products
- genomics-online: gRNA clones - Search results for available BNIP3L gene related products
- genomics-online: primer clones - Search results for available BNIP3L gene related products
- genomics-online: shRNA clones - Search results for available BNIP3L gene related products
Sources for BNIP3L Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems