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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homo... See more...
Aliases for BMP8B Gene
Aliases for BMP8B Gene
External Ids for BMP8B Gene
- HGNC: 1075
- NCBI Entrez Gene: 656
- Ensembl: ENSG00000116985
- OMIM®: 602284
- UniProtKB/Swiss-Prot: P34820
Previous HGNC Symbols for BMP8B Gene
- BMP8
Previous GeneCards Identifiers for BMP8B Gene
- GC01M039638
- GC01M039639
- GC01M039892
- GC01M039996
- GC01M040222
- GC01M038342
Summaries for BMP8B Gene
-
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
GeneCards Summary for BMP8B Gene
BMP8B (Bone Morphogenetic Protein 8b) is a Protein Coding gene. Diseases associated with BMP8B include Vestibulocochlear Nerve Disease and Vestibular Neuronitis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is BMP8A.
UniProtKB/Swiss-Prot Summary for BMP8B Gene
-
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity).
Additional gene information for BMP8B Gene
- HGNC (1075)
- NCBI Entrez Gene (656)
- Ensembl (ENSG00000116985)
- OMIM® (602284)
- UniProtKB/Swiss-Prot (P34820)
- Open Targets Platform(ENSG00000116985)
- Alliance of Genome Resources
- Search for BMP8B at DataMed
- Search for BMP8B at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BMP8B Gene
Genomics for BMP8B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for BMP8B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around BMP8B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BMP8B
- Top Transcription factor binding sites by QIAGEN in the BMP8B gene promoter:
-
- AML1a
- CP2
- HSF1 (long)
- HSF1short
- NF-kappaB
- NF-kappaB1
- SREBP-1a
- SREBP-1b
- SREBP-1c
- TGIF
Genomic Locations for BMP8B Gene
Latest Assembly
- chr1:39,757,182-39,788,865
- (GRCh38/hg38)
- Size:
- 31,684 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:40,222,854-40,254,537
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 31,684 bases
- Orientation:
- Minus strand
Genomic View for BMP8B Gene
Genes around BMP8B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.2 by HGNC
- 1p34.2 by Entrez Gene
- 1p34.2 by Ensembl
BMP8B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BMP8B Gene
Proteins for BMP8B Gene
-
Protein details for BMP8B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P34820-BMP8B_HUMAN
- Recommended name:
- Bone morphogenetic protein 8B
- Protein Accession:
- P34820
- E7EMY8
- Q32NE5
- Q53ZM7
- Q9NUF0
Protein attributes for BMP8B Gene
- Size:
- 402 amino acids
- Molecular mass:
- 44768 Da
- Quaternary structure:
-
- Homodimer; disulfide-linked.
Protein Expression for BMP8B Gene
Post-translational modifications for BMP8B Gene
Other Protein References for BMP8B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences BMP8B Antibody
- G Biosciences Immunotag™ BMP8B Antibody
- GeneTex Anti-BMP8b antibody and Anti-BMP8b antibody [GT1017]
-
Custom Antibody ServicesOriGene Antibodies for BMP8B
- Novus Biologicals Antibodies for BMP8B
- Invitrogen Antibodies for BMP8B (AFLGC-BMP8B)
- antibodies-online: Show 33 available BMP-8 Antibodies ranked by validation data
-
Santa Cruz Biotechnology (SCBT) Antibodies for BMP8B
Protein products for research
-
OriGene Purified Proteins for BMP8B
- Search Origene for MassSpec and Protein Over-expression Lysates for BMP8B
- Origene Custom Protein Services for BMP8B
- ProSpec Recombinant Proteins for BMP8B
-
Abcam proteins for BMP8B
Assay products for research
- Novus Biologicals ELISA Kits for BMP8B
No data available for DME Specific Peptides for BMP8B Gene
Domains & Families for BMP8B Gene
Gene Families for BMP8B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for BMP8B Gene
- InterPro:
- Blocks:
-
- Transforming growth factor beta (TGFb), N-terminal
- Transforming growth factor beta (TGFb)
- Growth factor cystine knot superfamily signature
Suggested Antigen Peptide Sequences for BMP8B Gene
- GenScript: Design optimal peptide antigens:
-
- Osteogenic protein 2 (BMP8B_HUMAN)
- BMP8B protein (Q32NE5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P34820- Family:
-
- Belongs to the TGF-beta family.
Function for BMP8B Gene
Molecular function for BMP8B Gene
- UniProtKB/Swiss-Prot Function:
- Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity).
LifeMap Function Summary for BMP8B Gene
During embryonic development, BMP8B as signaling molecule is secreted from the following cells
- Trophoblast
It affects the following cells:
- Epiblast
BMP8B as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells:
Phenotypes From GWAS Catalog for BMP8B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005125 | cytokine activity | IBA | 21873635 |
| GO:0008083 | growth factor activity | IEA | -- |
| GO:0070700 | BMP receptor binding | IBA | 21873635 |
Phenotypes for BMP8B Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for BMP8B - Starting at $85 >
- * BMP8B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for BMP8B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BMP8B
-
Santa Cruz Biotechnology (SCBT) CRISPR for BMP8B
miRNA for BMP8B Gene
- miRTarBase miRNAs that target BMP8B
-
- hsa-miR-26b-5p (MIRT029797)
- hsa-miR-6855-5p (MIRT509102)
- hsa-miR-3170 (MIRT509103)
- hsa-miR-6807-5p (MIRT509104)
- hsa-miR-193b-5p (MIRT509105)
- hsa-miR-5589-5p (MIRT509106)
- hsa-miR-4731-5p (MIRT509107)
- hsa-miR-7155-5p (MIRT509108)
- hsa-miR-150-5p (MIRT509109)
- hsa-miR-186-3p (MIRT509110)
- hsa-miR-520h (MIRT509111)
- hsa-miR-520g-3p (MIRT509112)
- hsa-miR-512-3p (MIRT509113)
- hsa-miR-520e (MIRT509114)
- hsa-miR-520d-3p (MIRT509115)
- hsa-miR-520c-3p (MIRT509116)
- hsa-miR-520b (MIRT509117)
- hsa-miR-520a-3p (MIRT509118)
- hsa-miR-373-3p (MIRT509119)
- hsa-miR-372-3p (MIRT509120)
- hsa-miR-302e (MIRT509121)
- hsa-miR-302d-3p (MIRT509122)
- hsa-miR-302c-3p (MIRT509123)
- hsa-miR-302b-3p (MIRT509124)
- hsa-miR-302a-3p (MIRT509125)
- hsa-miR-93-5p (MIRT509126)
- hsa-miR-526b-3p (MIRT509127)
- hsa-miR-519d-3p (MIRT509128)
- hsa-miR-20b-5p (MIRT509129)
- hsa-miR-20a-5p (MIRT509130)
- hsa-miR-17-5p (MIRT509131)
- hsa-miR-106b-5p (MIRT509132)
- hsa-miR-106a-5p (MIRT509133)
- hsa-miR-6778-3p (MIRT516150)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BMP8B
- Browse OriGene Inhibitory RNA Products For BMP8B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BMP8B
Clone products for research
- Applied Biological Materials (abm): Clones for BMP8B - Starting at $45 >
- * BMP8B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for BMP8B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BMP8B
Cell Lines for research
-
Horizon Cell Lines for BMP8B
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BMP8B Gene
Localization for BMP8B Gene
Subcellular locations from UniProtKB/Swiss-Prot for BMP8B Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| plasma membrane | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| lysosome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for BMP8B Gene
Pathways & Interactions for BMP8B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | PEDF Induced Signaling |
MIF Mediated Glucocorticoid Regulation
.94
MIF Regulation of Innate Immune Cells
.94
PEDF Induced Signaling
.73
all-trans-Retinoic Acid Signaling in Brain
.71
RAR-Gamma-RXR-Alpha Degradation
.62
IL-6 Pathway
.61
|
NFAT Signaling and Lymphocyte Interactions
.57
PGC1Alpha Pathway
.51
STAT3 Pathway
.47
Endothelin-1 Signaling Pathway
.46
Glucocorticoid Receptor Signaling
.43
|
| 2 | TGF-Beta Pathway |
MAPK Family Pathway
.60
TGF-Beta Pathway
.60
JAK-STAT Pathway
.57
|
JNK Pathway
.51
Regulation of eIF4 and p70S6K
.43
SOCS Pathway
.40
|
| 3 | Akt Signaling |
Akt Signaling
.60
p38 Signaling
.60
|
Tec Kinases Signaling
.55
|
| 4 | ERK Signaling |
ERK Signaling
.61
Rho Family GTPases
.61
|
Molecular Mechanisms of Cancer
.51
|
| 5 | PAK Pathway |
Antioxidant Action of Vitamin-C
.56
|
PAK Pathway
.56
|
Pathways by source for BMP8B Gene
4 KEGG pathways for BMP8B Gene
27 Qiagen pathways for BMP8B Gene
- Akt Signaling
- all-trans-Retinoic Acid Signaling in Brain
- Antioxidant Action of Vitamin-C
- Endothelin-1 Signaling Pathway
- ERK Signaling
Interacting Proteins for BMP8B Gene
Selected Interacting proteins:
P34820-BMP8B_HUMAN
ENSP00000361915
for BMP8B Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for BMP8B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001501 | skeletal system development | TAS | 1460021 |
| GO:0001503 | ossification | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | IBA | 21873635 |
| GO:0030154 | cell differentiation | IEA | -- |
No data available for SIGNOR curated interactions for BMP8B Gene
Drugs & Compounds for BMP8B Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6959 |
Transcripts for BMP8B Gene
mRNA/cDNA for BMP8B Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000372827 4826 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for BMP8B - Starting at $85 >
- * BMP8B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for BMP8B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BMP8B
-
Santa Cruz Biotechnology (SCBT) CRISPR for BMP8B
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BMP8B
- Browse OriGene Inhibitory RNA Products For BMP8B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BMP8B
Clone products for research
- Applied Biological Materials (abm): Clones for BMP8B - Starting at $45 >
- * BMP8B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for BMP8B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BMP8B
Relevant External Links for BMP8B Gene
- GeneLoc Exon Structure for
- BMP8B
Expression for BMP8B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
mRNA differential expression in normal tissues according to GTEx for BMP8B Gene
This gene is overexpressed in Nerve - Tibial (x11.6).
This gene is overexpressed in Heart (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BMP8B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BMP8B
SOURCE GeneReport for Unigene cluster for BMP8B Gene:
Hs.734367Evidence on tissue expression from TISSUES for BMP8B Gene
- Nervous system(4.4)
- Thyroid gland(2.2)
Primer products for research
-
OriGene qPCR primer pairs for BMP8B
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BMP8B Gene
Orthologs for BMP8B Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | BMP8B 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | -- 30 |
|
ManyToMany | |
| LOC100855618 29 |
|
||||
| -- 30 |
|
ManyToMany | |||
| Cow (Bos Taurus) |
Mammalia | BMP8A 29 |
|
||
| -- 30 |
|
ManyToMany | |||
| -- 30 |
|
ManyToMany | |||
| Mouse (Mus musculus) |
Mammalia | Bmp8a 30 |
|
ManyToMany | |
| Bmp8b 30 |
|
ManyToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 30 |
|
OneToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 30 |
|
OneToMany | |
| Chicken (Gallus gallus) |
Aves | BMP8B 29 |
|
||
| -- 30 |
|
OneToMany | |||
| Lizard (Anolis carolinensis) |
Reptilia | -- 30 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | bmp8b 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | bmp8a 29 30 |
|
OneToMany |
- Species where no ortholog for BMP8B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for BMP8B Gene
- ENSEMBL:
- Gene Tree for BMP8B (if available)
- TreeFam:
- Gene Tree for BMP8B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for BMP8B: view image
- Alliance of Genome Resources:
- Additional Orthologs for BMP8B
Paralogs for BMP8B Gene
Paralogs for BMP8B Gene
(4) SIMAP similar genes for BMP8B Gene using alignment to 3 proteins:
- BMP8B_HUMAN
- E7EMY8_HUMAN
- Q32NE5_HUMAN
Pseudogenes.org Pseudogenes for BMP8B Gene
Variants for BMP8B Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BMP8B Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs138246844 | Likely Benign: not provided. Benign: not provided | 39,763,173(-) |
C/GC/T NM_001720.5(BMP8B):c.978G>C (p.Ser326=) |
SYNONYMOUS_VARIANT,INTRON | |
| rs138571171 | Benign: not provided | 39,763,082(-) |
T/C NM_001720.5(BMP8B):c.1059+10A>G |
INTRON | |
| rs179472 | Benign: not provided | 39,764,664(-) |
C/G NM_001720.5(BMP8B):c.827G>C (p.Ser276Thr) |
MISSENSE | |
| rs192079535 | Benign: not provided | 39,762,513(-) |
T/C NM_001720.5(BMP8B):c.1059+579A>G |
INTRON | |
| rs370056406 | Likely Benign: not provided | 39,775,019(-) |
C/T NM_001720.5(BMP8B):c.354G>A (p.Leu118=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv152n100 | CNV | gain | 25217958 |
| dgv153n100 | CNV | gain | 25217958 |
| dgv15n27 | CNV | gain | 19166990 |
| esv2758933 | CNV | loss | 17122850 |
| esv3561048 | CNV | deletion | 23714750 |
| nsv1075454 | CNV | deletion | 25765185 |
| nsv1116447 | OTHER | inversion | 24896259 |
| nsv1136078 | CNV | deletion | 24896259 |
| nsv546063 | CNV | gain | 21841781 |
| nsv7177 | OTHER | inversion | 18451855 |
| nsv945894 | CNV | duplication | 23825009 |
| nsv945895 | CNV | duplication | 23825009 |
| nsv950654 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
91.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.44;
64.05% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BMP8B Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BMP8B Gene
Disorders for BMP8B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| vestibulocochlear nerve disease |
|
|
| vestibular neuronitis |
|
|
| photoallergic dermatitis |
|
|
| breast giant fibroadenoma |
|
|
| achondroplasia |
|
|
Search BMP8B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for BMP8B
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for BMP8B Gene
Publications for BMP8B Gene
- Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis. (PMID: 1460021) Ozkaynak E … Oppermann H (The Journal of biological chemistry 1992) 2 3 4 22
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 40
- A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 40
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
- Genetic variations in humans associated with differences in the course of hepatitis C. (PMID: 15063762) Saito T … Kawata S (Biochemical and biophysical research communications 2004) 3 40
ExternalLinks
Products for BMP8B Gene
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- Abcam proteins for BMP8B
- Find your target
- Browse Primary Antibodies
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- VectorBuilder Stable cell line generation for BMP8B
- antibodies-online: Show 33 available BMP-8 Antibodies ranked by validation data
- antibodies-online: Search results for available BMP-8 related products ranked by validation data
- antibodies-online: Search results for available BMP-8 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for BMP8B
- Search Santa Cruz Biotechnology (SCBT) for BMP8B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for BMP8B
- Horizon Cell Lines for BMP8B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BMP8B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BMP8B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for BMP8B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BMP8B
Sources for BMP8B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources