Aliases for BMP2K Gene
External Ids for BMP2K Gene
Previous GeneCards Identifiers for BMP2K Gene
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BMP2K Gene
BMP2K (BMP2 Inducible Kinase) is a Protein Coding gene. Diseases associated with BMP2K include Ulnar Neuropathy and Frontal Lobe Neoplasm. Among its related pathways are Transcriptional misregulation in cancer. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AAK1.
UniProtKB/Swiss-Prot Summary for BMP2K Gene
May be involved in osteoblast differentiation.