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Aliases for BIRC3 Gene

Aliases for BIRC3 Gene

  • Baculoviral IAP Repeat Containing 3 2 3 5
  • Inhibitor Of Apoptosis Protein 1 2 3 4
  • Apoptosis Inhibitor 2 2 3 4
  • RING-Type E3 Ubiquitin Transferase BIRC3 3 4
  • TNFR2-TRAF-Signaling Complex Protein 1 3 4
  • TNFR2-TRAF Signaling Complex Protein 2 3
  • Cellular Inhibitor Of Apoptosis 2 3 4
  • Mammalian IAP Homolog C 2 3
  • RING Finger Protein 49 3 4
  • IAP Homolog C 3 4
  • C-IAP2 3 4
  • HIAP1 3 4
  • RNF49 3 4
  • API2 3 4
  • MIHC 3 4
  • Baculoviral IAP Repeat-Containing Protein 3 3
  • Baculoviral IAP Repeat-Containing 3 2
  • EC 2.3.2.27 4
  • HIAP-1 4
  • CIAP2 3
  • HAIP1 3
  • IAP-1 3
  • MALT2 3
  • AIP1 3

External Ids for BIRC3 Gene

Previous HGNC Symbols for BIRC3 Gene

  • API2

Previous GeneCards Identifiers for BIRC3 Gene

  • GC11P104381
  • GC11P103545
  • GC11P102222
  • GC11P101725
  • GC11P101693
  • GC11P098114
  • GC11P102188

Summaries for BIRC3 Gene

Entrez Gene Summary for BIRC3 Gene

  • This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]

CIViC summary for BIRC3 Gene

GeneCards Summary for BIRC3 Gene

BIRC3 (Baculoviral IAP Repeat Containing 3) is a Protein Coding gene. Diseases associated with BIRC3 include Lymphoma, Mucosa-Associated Lymphoid Type and Marginal Zone B-Cell Lymphoma. Among its related pathways are Focal Adhesion and NF-kappa B signaling pathway. Gene Ontology (GO) annotations related to this gene include ligase activity and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is BIRC2.

UniProtKB/Swiss-Prot for BIRC3 Gene

  • Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.

Gene Wiki entry for BIRC3 Gene

Additional gene information for BIRC3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BIRC3 Gene

Genomics for BIRC3 Gene

GeneHancer (GH) Regulatory Elements for BIRC3 Gene

Promoters and enhancers for BIRC3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J102311 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 673.4 +0.3 289 13.2 HDGF PKNOX1 SMAD1 SIN3A FEZF1 ZNF2 IRF4 YY1 ZNF207 ZNF143 BIRC3 BIRC2 ENSG00000256916 MMP20 MMP7 TMEM123 RNU6-952P
GH11J102267 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 655.9 -48.3 -48337 3.9 PKNOX1 ARID4B SIN3A DMAP1 GLIS2 ELK1 ZNF143 FOS DEK SP3 BIRC3 LOC105369460 DYNC2H1 ENSG00000254422 BIRC2 RPS6P17
GH11J102303 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 19.5 -11.5 -11453 4.7 RFX5 RCOR1 FOS CEBPB ZNF398 REST SP1 ATF4 MAFF HMBOX1 ENSG00000270868 BIRC3 BIRC2 MMP7 RPS6P17
GH11J102287 Enhancer 1.2 Ensembl ENCODE dbSUPER 20.4 -28.4 -28351 3.8 ARID4B RAD21 RFX5 YY1 ARID2 ZNF143 RCOR1 BCLAF1 DEK ZNF654 BIRC3 RPS6P17 LOC105369460
GH11J102293 Enhancer 1.2 Ensembl ENCODE dbSUPER 20 -22.5 -22464 2.5 CTCF PKNOX1 ARID4B KAT7 BATF ZNF2 RBPJ RAD21 RFX5 ZNF143 RPS6P17 BIRC3 BIRC2 LOC105369460
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BIRC3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the BIRC3 gene promoter:
  • AP-1
  • CREB
  • deltaCREB
  • ATF-2
  • c-Jun

Genomic Locations for BIRC3 Gene

Genomic Locations for BIRC3 Gene
chr11:102,317,373-102,339,403
(GRCh38/hg38)
Size:
22,031 bases
Orientation:
Plus strand
chr11:102,188,194-102,210,134
(GRCh37/hg19)
Size:
21,941 bases
Orientation:
Plus strand

Genomic View for BIRC3 Gene

Genes around BIRC3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BIRC3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BIRC3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BIRC3 Gene

Proteins for BIRC3 Gene

  • Protein details for BIRC3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13489-BIRC3_HUMAN
    Recommended name:
    Baculoviral IAP repeat-containing protein 3
    Protein Accession:
    Q13489
    Secondary Accessions:
    • Q16628
    • Q9HC27
    • Q9UP46

    Protein attributes for BIRC3 Gene

    Size:
    604 amino acids
    Molecular mass:
    68372 Da
    Quaternary structure:
    • Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form a heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Interaction with TRAF2 is required for ubiquitination of IKBKE, degradation of NFKBIA and activation of NF-kappa-B. Interacts with RIP1, RIP2, RIP3, RIP4 and USP19.

    Three dimensional structures from OCA and Proteopedia for BIRC3 Gene

neXtProt entry for BIRC3 Gene

Post-translational modifications for BIRC3 Gene

  • Auto-ubiquitinated and degraded by the proteasome in apoptotic cells.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BIRC3 Gene

Antibody Products

  • R&D Systems Antibodies for BIRC3 (cIAP-2/HIAP-1)
  • Abcam antibodies for BIRC3

No data available for DME Specific Peptides for BIRC3 Gene

Domains & Families for BIRC3 Gene

Gene Families for BIRC3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Enzymes
  • Plasma proteins
  • Potential drug targets
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for BIRC3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13489

UniProtKB/Swiss-Prot:

BIRC3_HUMAN :
  • Belongs to the IAP family.
Family:
  • Belongs to the IAP family.
genes like me logo Genes that share domains with BIRC3: view

Function for BIRC3 Gene

Molecular function for BIRC3 Gene

UniProtKB/Swiss-Prot Function:
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.
UniProtKB/Swiss-Prot CatalyticActivity:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
UniProtKB/Swiss-Prot EnzymeRegulation:
USP19 regulates the stability of BIRC3/c-IAP2 by preventing its ubiquitination.

Enzyme Numbers (IUBMB) for BIRC3 Gene

Gene Ontology (GO) - Molecular Function for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity TAS --
GO:0005515 protein binding IPI 10929712
GO:0016740 transferase activity EXP 19008929
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with BIRC3: view
genes like me logo Genes that share phenotypes with BIRC3: view

Human Phenotype Ontology for BIRC3 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for BIRC3 Gene

MGI Knock Outs for BIRC3:

Animal Model Products

miRNA for BIRC3 Gene

Clone Products

  • Addgene plasmids for BIRC3

No data available for Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for BIRC3 Gene

Localization for BIRC3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BIRC3 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BIRC3 gene
Compartment Confidence
nucleus 5
cytosol 5
mitochondrion 2
plasma membrane 1
extracellular 1
peroxisome 1
endoplasmic reticulum 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoplasm (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IEA 15665297
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA,IDA 15665297
GO:0005829 cytosol TAS --
GO:0032991 protein-containing complex IEA --
genes like me logo Genes that share ontologies with BIRC3: view

Pathways & Interactions for BIRC3 Gene

genes like me logo Genes that share pathways with BIRC3: view

SIGNOR curated interactions for BIRC3 Gene

Activates:
Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS --
GO:0006915 apoptotic process IEA --
GO:0007166 cell surface receptor signaling pathway TAS 8548810
GO:0007249 I-kappaB kinase/NF-kappaB signaling TAS --
GO:0007283 spermatogenesis IEA --
genes like me logo Genes that share ontologies with BIRC3: view

Drugs & Compounds for BIRC3 Gene

(33) Drugs for BIRC3 Gene - From: DGIdb and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
GDC-0152 Investigational Pharma IAP antagonist,potent amd samll-molecule 0
LCL161 Pharma Antagonist Antagonist of IAPs inhibitor, Inhibitor of apoptosis proteins (IAPS) antagonist 0
AT-406 (SM-406) Pharma 0
BV6 Pharma 0
SM-164 Pharma Anticancer agent 0

(12) Additional Compounds for BIRC3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with BIRC3: view

Transcripts for BIRC3 Gene

mRNA/cDNA for BIRC3 Gene

Unigene Clusters for BIRC3 Gene

Baculoviral IAP repeat containing 3:
Representative Sequences:

Clone Products

  • Addgene plasmids for BIRC3

Alternative Splicing Database (ASD) splice patterns (SP) for BIRC3 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b
SP1: - - - -
SP2: -
SP3:
SP4:
SP5: -

Relevant External Links for BIRC3 Gene

GeneLoc Exon Structure for
BIRC3
ECgene alternative splicing isoforms for
BIRC3

Expression for BIRC3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BIRC3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for BIRC3 Gene

This gene is overexpressed in Blymphocyte (33.1), Peripheral blood mononuclear cells (27.7), and CD4 Tcells (8.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BIRC3 Gene



Protein tissue co-expression partners for BIRC3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BIRC3 Gene:

BIRC3

SOURCE GeneReport for Unigene cluster for BIRC3 Gene:

Hs.127799

mRNA Expression by UniProt/SwissProt for BIRC3 Gene:

Q13489-BIRC3_HUMAN
Tissue specificity: Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.

Evidence on tissue expression from TISSUES for BIRC3 Gene

  • Liver(4.4)
  • Intestine(2.9)
  • Stomach(2.7)
  • Lung(2.6)
  • Lymph node(2.6)
  • Spleen(2.5)
  • Blood(2.3)
  • Heart(2.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for BIRC3 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • integumentary
  • nervous
  • respiratory
Regions:
Head and neck:
  • brain
  • head
Thorax:
  • esophagus
  • lung
Abdomen:
  • intestine
  • large intestine
  • stomach
Pelvis:
  • rectum
General:
  • skin
  • sweat gland
genes like me logo Genes that share expression patterns with BIRC3: view

No data available for mRNA differential expression in normal tissues for BIRC3 Gene

Orthologs for BIRC3 Gene

This gene was present in the common ancestor of animals.

Orthologs for BIRC3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BIRC3 34 33
  • 99.12 (n)
OneToOne
cow
(Bos Taurus)
Mammalia BIRC3 34 33
  • 88.69 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Birc3 16 34 33
  • 77.19 (n)
rat
(Rattus norvegicus)
Mammalia Birc3 33
  • 76.91 (n)
dog
(Canis familiaris)
Mammalia BIRC3 34 33
  • 76.43 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 74 (a)
ManyToMany
-- 34
  • 72 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 73 (a)
OneToMany
chicken
(Gallus gallus)
Aves ITA 34
  • 70 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 67 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii birc2 34
  • 51 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Iap2 34 35
  • 32 (a)
ManyToMany
th 34
  • 24 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 55 (a)
ManyToMany
-- 34
  • 41 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
-- 34
  • 29 (a)
ManyToMany
-- 34
  • 28 (a)
ManyToMany
-- 34
  • 26 (a)
ManyToMany
-- 34
  • 21 (a)
ManyToMany
Species where no ortholog for BIRC3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BIRC3 Gene

ENSEMBL:
Gene Tree for BIRC3 (if available)
TreeFam:
Gene Tree for BIRC3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for BIRC3: view image

Paralogs for BIRC3 Gene

Paralogs for BIRC3 Gene

(19) SIMAP similar genes for BIRC3 Gene using alignment to 3 proteins:

  • BIRC3_HUMAN
  • H0YCJ5_HUMAN
  • L8E7L9_HUMAN
genes like me logo Genes that share paralogs with BIRC3: view

Variants for BIRC3 Gene

Sequence variations from dbSNP and Humsavar for BIRC3 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000216597 -- 102,339,222(+) A/G/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000279607 -- 102,326,827(+) G/A intron_variant
rs1000310889 -- 102,331,821(+) A/C intron_variant
rs1000399584 -- 102,332,744(+) C/G intron_variant
rs1000616550 -- 102,338,992(+) T/C 3_prime_UTR_variant, genic_downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for BIRC3 Gene

Variant ID Type Subtype PubMed ID
dgv1269n100 CNV gain 25217958
nsv556141 CNV gain 21841781
nsv556142 CNV loss 21841781

Variation tolerance for BIRC3 Gene

Residual Variation Intolerance Score: 29.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.84; 34.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for BIRC3 Gene

Human Gene Mutation Database (HGMD)
BIRC3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
BIRC3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BIRC3 Gene

Disorders for BIRC3 Gene

MalaCards: The human disease database

(15) MalaCards diseases for BIRC3 Gene - From: HGMD, Orphanet, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search BIRC3 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

BIRC3_HUMAN
  • Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.

Additional Disease Information for BIRC3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with BIRC3: view

No data available for Genatlas for BIRC3 Gene

Publications for BIRC3 Gene

  1. Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type. (PMID: 11066071) Baens M … Marynen P (Genes, chromosomes & cancer 2000) 3 4 22 58
  2. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. (PMID: 8552191) Liston P … Korneluk RG (Nature 1996) 2 3 4 58
  3. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. (PMID: 8548810) Rothe M … Goeddel DV (Cell 1995) 2 3 4 58
  4. IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. (PMID: 23453969) Zhou AY … Hahn WC (Cell reports 2013) 3 4 58
  5. Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. (PMID: 21447281) Damgaard RB … Gyrd-Hansen M (Discovery medicine 2011) 3 4 58

Products for BIRC3 Gene

  • Addgene plasmids for BIRC3

Sources for BIRC3 Gene

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