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Aliases for BICRAL Gene

Aliases for BICRAL Gene

  • BRD4 Interacting Chromatin Remodeling Complex Associated Protein Like 2 3 5
  • KIAA0240 2 3 4
  • Glioma Tumor Suppressor Candidate Region Gene 1 Protein-Like 3 4
  • GLTSCR1 Like 2 3
  • GLTSCR1L 3 4
  • BRD4 Interacting Chromatin Remodelling Complex Associated Protein Like 3
  • BRD4-Interacting Chromatin-Remodeling Complex-Associated Protein-Like 3
  • GLTSCR1-Like 2

External Ids for BICRAL Gene

Previous HGNC Symbols for BICRAL Gene

  • KIAA0240
  • GLTSCR1L

Previous GeneCards Identifiers for BICRAL Gene

  • GC06P042753

Summaries for BICRAL Gene

GeneCards Summary for BICRAL Gene

BICRAL (BRD4 Interacting Chromatin Remodeling Complex Associated Protein Like) is a Protein Coding gene. An important paralog of this gene is BICRA.

Additional gene information for BICRAL Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BICRAL Gene

Genomics for BICRAL Gene

GeneHancer (GH) Regulatory Elements for BICRAL Gene

Promoters and enhancers for BICRAL Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J042780 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 695.5 +37.1 37134 7.4 HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B BICRAL LOC401261 ZNF318 CUL7 ABCC10 POLH GTPBP2 POLR1C RPS2P29 RPL34P14
GH06J042744 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.7 -0.4 -419 4.8 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 BICRAL PIR40096 PIR49302 PIR52070 TBCC POLH XPO5 ZNF318 RRP36 FRS3
GH06J042819 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 650.2 +74.1 74068 2.9 CTCF CEBPB RAD21 PRDM1 BICRAL RPL7L1 RNU6-890P KLC4 MRPL2 PPP2R5D KLHDC3 MEA1 LOC401261
GH06J043624 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 34 +881.1 881081 7.4 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF263 SP3 GTPBP2 MAD2L1BP ZNF318 POLH ABCC10 RPS2P29 RRP36 CUL7 BICRAL XPO5
GH06J042040 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 22.9 -700.6 -700629 11 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF263 SP3 CCND3 TAF8 PIR49026 MED20 BICRAL ENSG00000124593 RNU6-761P ENSG00000207371 BYSL FRS3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BICRAL on UCSC Golden Path with GeneCards custom track

Genomic Locations for BICRAL Gene

Genomic Locations for BICRAL Gene
chr6:42,746,958-42,868,560
(GRCh38/hg38)
Size:
121,603 bases
Orientation:
Plus strand
chr6:42,749,765-42,836,298
(GRCh37/hg19)

Genomic View for BICRAL Gene

Genes around BICRAL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BICRAL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BICRAL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BICRAL Gene

Proteins for BICRAL Gene

  • Protein details for BICRAL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AI39-BICRL_HUMAN
    Recommended name:
    BRD4-interacting chromatin-remodeling complex-associated protein-like
    Protein Accession:
    Q6AI39
    Secondary Accessions:
    • A1L3W2
    • Q5TFZ3
    • Q92514

    Protein attributes for BICRAL Gene

    Size:
    1079 amino acids
    Molecular mass:
    115084 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA13246.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for BICRAL Gene

Post-translational modifications for BICRAL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BICRAL Gene

No data available for DME Specific Peptides for BICRAL Gene

Domains & Families for BICRAL Gene

Gene Families for BICRAL Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for BICRAL Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BICRAL: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BICRAL Gene

Function for BICRAL Gene

Phenotypes From GWAS Catalog for BICRAL Gene

genes like me logo Genes that share phenotypes with BICRAL: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BICRAL Gene

Localization for BICRAL Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BICRAL gene
Compartment Confidence
nucleus 4
cytosol 3
extracellular 1
cytoskeleton 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BICRAL Gene

Pathways & Interactions for BICRAL Gene

SuperPathways for BICRAL Gene

No Data Available

Gene Ontology (GO) - Biological Process for BICRAL Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BICRAL Gene

Drugs & Compounds for BICRAL Gene

No Compound Related Data Available

Transcripts for BICRAL Gene

mRNA/cDNA for BICRAL Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BICRAL Gene

No ASD Table

Relevant External Links for BICRAL Gene

GeneLoc Exon Structure for
BICRAL
ECgene alternative splicing isoforms for
BICRAL

Expression for BICRAL Gene

NURSA nuclear receptor signaling pathways regulating expression of BICRAL Gene:

BICRAL
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BICRAL Gene

Orthologs for BICRAL Gene

This gene was present in the common ancestor of chordates.

Orthologs for BICRAL Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GLTSCR1L 34 33
  • 99.54 (n)
OneToOne
dog
(Canis familiaris)
Mammalia GLTSCR1L 34 33
  • 92.77 (n)
OneToOne
cow
(Bos Taurus)
Mammalia GLTSCR1L 34 33
  • 90.93 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gltscr1l 33
  • 86.91 (n)
mouse
(Mus musculus)
Mammalia Gltscr1l 34 33
  • 85.53 (n)
OneToOne
Bicral 16
oppossum
(Monodelphis domestica)
Mammalia GLTSCR1L 34
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GLTSCR1L 34
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0240 33
  • 76.39 (n)
GLTSCR1L 34
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GLTSCR1L 34
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gltscr1l 33
  • 61.43 (n)
zebrafish
(Danio rerio)
Actinopterygii gltscr1l 34 33
  • 55.67 (n)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 26 (a)
OneToMany
Species where no ortholog for BICRAL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BICRAL Gene

ENSEMBL:
Gene Tree for BICRAL (if available)
TreeFam:
Gene Tree for BICRAL (if available)
Aminode:
Evolutionary constrained regions (ECRs) for BICRAL: view image

Paralogs for BICRAL Gene

Paralogs for BICRAL Gene

genes like me logo Genes that share paralogs with BICRAL: view

Variants for BICRAL Gene

Sequence variations from dbSNP and Humsavar for BICRAL Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs193921035 uncertain-significance, Malignant tumor of prostate 42,830,111(+) A/G coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs1000032114 -- 42,761,050(+) A/G/T genic_upstream_transcript_variant, intron_variant
rs1000038181 -- 42,855,127(+) C/T intron_variant
rs1000050543 -- 42,769,688(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000087928 -- 42,820,826(+) G/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for BICRAL Gene

Variant ID Type Subtype PubMed ID
esv2668024 CNV deletion 23128226
esv3576145 CNV gain 25503493
esv3608805 CNV loss 21293372
nsv1017398 CNV gain 25217958
nsv433480 CNV loss 18776910
nsv830650 CNV loss 17160897
nsv830651 CNV loss 17160897
nsv958388 CNV deletion 24416366

Variation tolerance for BICRAL Gene

Residual Variation Intolerance Score: 21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.30; 53.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for BICRAL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BICRAL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BICRAL Gene

Disorders for BICRAL Gene

No disorders were found for BICRAL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BICRAL Gene

Publications for BICRAL Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  2. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1996) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58

Products for BICRAL Gene

Sources for BICRAL Gene

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