Aliases for BDNF-AS Gene

Data sources for BDNF-AS Gene:

Subcategory (RNA class) for BDNF-AS Gene


Aliases for BDNF-AS Gene

External Ids for BDNF-AS Gene

Previous HGNC Symbols for BDNF-AS Gene


Previous GeneCards Identifiers for BDNF-AS Gene

  • GC11P027531
  • GC11P027510

Summaries for BDNF-AS Gene

GeneCards Summary for BDNF-AS Gene

BDNF-AS (BDNF Antisense RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with BDNF-AS include Depression and Huntington Disease.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BDNF-AS Gene

Genomics for BDNF-AS Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for BDNF-AS Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BDNF-AS on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for BDNF-AS Gene

Latest Assembly
191,419 bases
Plus strand

Previous Assembly
(GRCh37/hg19 by Entrez Gene)
191,320 bases
Plus strand

(GRCh37/hg19 by Ensembl)
191,337 bases
Plus strand

Genomic View for BDNF-AS Gene

Genes around BDNF-AS on UCSC Golden Path with GeneCards custom track
BDNF-AS in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
BDNF-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BDNF-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BDNF-AS Gene

Proteins for BDNF-AS Gene

Post-translational modifications for BDNF-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for BDNF-AS Gene

Domains & Families for BDNF-AS Gene

Gene Families for BDNF-AS Gene

genes like me logo Genes that share domains with BDNF-AS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for BDNF-AS Gene

Function for BDNF-AS Gene

Phenotypes From GWAS Catalog for BDNF-AS Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BDNF-AS Gene

Localization for BDNF-AS Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BDNF-AS gene
Compartment Confidence
cytoskeleton 2
nucleus 2
plasma membrane 1
extracellular 1
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BDNF-AS Gene

Pathways & Interactions for BDNF-AS Gene

PathCards logo

SuperPathways for BDNF-AS Gene

No Data Available

Gene Ontology (GO) - Biological Process for BDNF-AS Gene


No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for BDNF-AS Gene

Drugs & Compounds for BDNF-AS Gene

(1) Drugs for BDNF-AS Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
antipsychotics Pharma 0
genes like me logo Genes that share compounds with BDNF-AS: view

Transcripts for BDNF-AS Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for BDNF-AS Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000361BAF_9606 lncRNA 596 4

Ensembl: ENST00000530313 (view in UCSC) ,

LncBook: HSALNT0173397,

LNCipedia: BDNF-AS:19,


URS000075AB2C_9606 lncRNA 2036 3

RefSeq: NR_033312,

Ensembl: ENST00000499568 (view in UCSC) ,

LncBook: HSALNT0173363,

URS000075B01C_9606 lncRNA 1437 3

RefSeq: NR_033315,

Ensembl: ENST00000500662 (view in UCSC) ,

LncBook: HSALNT0173354,

URS000046132E_9606 lncRNA 572 3

Ensembl: ENST00000532965 (view in UCSC) ,

LncBook: HSALNT0173337, HSALNT0173338,


URS000075E443_9606 lncRNA 2320 2

RefSeq: NR_002832,

Ensembl: ENST00000499008 (view in UCSC) ,

BDNF-AS in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for BDNF-AS Gene

29 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BDNF-AS Gene

No ASD Table

Relevant External Links for BDNF-AS Gene

GeneLoc Exon Structure for

Expression for BDNF-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for BDNF-AS Gene

mRNA differential expression in normal tissues according to GTEx for BDNF-AS Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x4.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BDNF-AS

SOURCE GeneReport for Unigene cluster for BDNF-AS Gene:

genes like me logo Genes that share expression patterns with BDNF-AS: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BDNF-AS Gene

Orthologs for BDNF-AS Gene

Evolution for BDNF-AS Gene

Gene Tree for BDNF-AS (if available)
Gene Tree for BDNF-AS (if available)

No data available for Orthologs for BDNF-AS Gene

Paralogs for BDNF-AS Gene

No data available for Paralogs for BDNF-AS Gene

Variants for BDNF-AS Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BDNF-AS Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
981928 Likely Pathogenic: Obesity 27,658,008(+) C/T
NM_001709.5(BDNF):c.557G>A (p.Cys186Tyr)
rs1287429853 Uncertain Significance: not specified 27,674,268(+) CTG/C
rs138287649 Likely Benign: not provided 27,657,923(+) G/A
NM_001709.5(BDNF):c.642C>T (p.Tyr214=)
rs148736382 Benign: not provided 27,658,244(+) G/C
NM_001709.5(BDNF):c.321C>G (p.Leu107=)
rs1554931219 Likely Pathogenic: Inborn genetic diseases 27,658,063(+) C/A
NM_001709.5(BDNF):c.502G>T (p.Glu168Ter)

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for BDNF-AS Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for BDNF-AS Gene

Variant ID Type Subtype PubMed ID
dgv135e201 CNV deletion 23290073
dgv607n106 CNV deletion 24896259
esv1476336 CNV insertion 17803354
esv1745758 CNV deletion 17803354
esv2064689 CNV deletion 18987734
esv2672678 CNV deletion 23128226
esv2744288 CNV deletion 23290073
esv2744290 CNV deletion 23290073
esv2744292 CNV deletion 23290073
esv2744293 CNV deletion 23290073
esv2744294 CNV deletion 23290073
esv3258052 CNV deletion 24192839
esv3357461 CNV insertion 20981092
esv3454 CNV loss 18987735
esv3547509 CNV deletion 23714750
esv3625772 CNV loss 21293372
esv3625773 CNV loss 21293372
esv5866 CNV loss 19470904
nsv1076609 CNV deletion 25765185
nsv1141919 OTHER inversion 24896259
nsv474533 CNV novel sequence insertion 20440878
nsv819223 CNV gain 19587683
nsv832095 CNV gain 17160897
nsv957875 CNV insertion 24416366
nsv958620 CNV deletion 24416366
nsv971997 CNV duplication 23825009
nsv982998 CNV duplication 23825009

Additional Variant Information for BDNF-AS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BDNF-AS Gene

Disorders for BDNF-AS Gene

MalaCards: The human disease database

(17) MalaCards diseases for BDNF-AS Gene - From: LNC, CVR, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for BDNF-AS

genes like me logo Genes that share disorders with BDNF-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BDNF-AS Gene

Publications for BDNF-AS Gene

  1. Knockdown of long noncoding antisense RNA brain-derived neurotrophic factor attenuates hypoxia/reoxygenation-induced nerve cell apoptosis through the BDNF-TrkB-PI3K/Akt signaling pathway. (PMID: 28777258) Zhong JB … Wu XY (Neuroreport 2017) 2 3
  2. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. (PMID: 22446693) Modarresi F … Wahlestedt C (Nature biotechnology 2012) 2 3
  3. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PMID: 19079260) Thorleifsson G … Stefansson K (Nature genetics 2009) 3 74
  4. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. (PMID: 15666411) Liu QR … Uhl GR (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005) 2 3
  5. In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors. (PMID: 32401758) Rodrigues de Bastos D … Nagai MA (PloS one 2020) 3

Products for BDNF-AS Gene

Sources for BDNF-AS Gene