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Aliases for BCRP2 Gene

Aliases for BCRP2 Gene

  • Breakpoint Cluster Region Pseudogene 2 2 3 5
  • Breakpoint Cluster Region-Like 2 2 3
  • BCR-2 3
  • BCRL2 3
  • BCR2 3

External Ids for BCRP2 Gene

Previous HGNC Symbols for BCRP2 Gene

  • BCR2
  • BCRL2

Previous GeneCards Identifiers for BCRP2 Gene

  • GC14M067022
  • GC22P021461
  • GC22P021467

Summaries for BCRP2 Gene

GeneCards Summary for BCRP2 Gene

BCRP2 (Breakpoint Cluster Region Pseudogene 2) is a Pseudogene.

Additional gene information for BCRP2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCRP2 Gene

Genomics for BCRP2 Gene

GeneHancer (GH) Regulatory Elements for BCRP2 Gene

Promoters and enhancers for BCRP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I021102 Enhancer 1.2 Ensembl ENCODE 550.8 0.0 -29 0.6 PKNOX1 CLOCK ATF1 SIN3A ZNF2 GTF3C2 ZNF121 GLIS2 ZNF143 ATF7 BCRP2 ENSG00000284665
GH22I021101 Enhancer 0.7 ENCODE 550.8 -1.4 -1429 0.2 INSM2 TSC22D4 ZNF644 ZNF335 FOSL1 CTBP1 GATA3 FOS EGR2 PHF21A BCRP2 ABHD17AP4 ENSG00000284665
GH22I020916 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 7.9 -184.1 -184119 5.7 HNRNPUL1 PKNOX1 CLOCK MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 CRKL SNAP29 MED15 LZTR1 SERPIND1 ZNF74 PPIL2 ENSG00000273343 KLHL22 ENSG00000225544
GH22I020697 Enhancer 1 Ensembl ENCODE 16.6 -405.5 -405515 1 HDAC1 SMAD1 RB1 RAD21 ZNF335 ZNF766 ARID2 EGR1 ZNF143 ATF7 BCRP5 SNAP29 SERPIND1 BCRP2 POM121L4P PIR43264
GH22I020947 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 8.1 -149.7 -149740 10.6 HDGF HNRNPUL1 PKNOX1 FOXA2 MLX ARID4B SIN3A YBX1 FEZF1 YY1 GC22P020955 LZTR1 SERPIND1 CRKL MED15 SNAP29 DGCR8 TRMT2A PI4KA PPIL2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BCRP2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for BCRP2 Gene

Genomic Locations for BCRP2 Gene
chr22:21,103,016-21,122,286
(GRCh38/hg38)
Size:
19,271 bases
Orientation:
Plus strand
chr22:21,457,305-21,476,575
(GRCh37/hg19)

Genomic View for BCRP2 Gene

Genes around BCRP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCRP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCRP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCRP2 Gene

Proteins for BCRP2 Gene

Post-translational modifications for BCRP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for BCRP2 Gene

Domains & Families for BCRP2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BCRP2 Gene

Function for BCRP2 Gene

Phenotypes From GWAS Catalog for BCRP2 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BCRP2 Gene

Localization for BCRP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BCRP2 Gene

Pathways & Interactions for BCRP2 Gene

SuperPathways for BCRP2 Gene

No Data Available

Interacting Proteins for BCRP2 Gene

Gene Ontology (GO) - Biological Process for BCRP2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BCRP2 Gene

Drugs & Compounds for BCRP2 Gene

No Compound Related Data Available

Transcripts for BCRP2 Gene

mRNA/cDNA for BCRP2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BCRP2 Gene

Breakpoint cluster region pseudogene 2:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BCRP2 Gene

No ASD Table

Relevant External Links for BCRP2 Gene

GeneLoc Exon Structure for
BCRP2
ECgene alternative splicing isoforms for
BCRP2

Expression for BCRP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BCRP2 Gene

mRNA differential expression in normal tissues according to GTEx for BCRP2 Gene

This gene is overexpressed in Testis (x11.2), Brain - Cerebellar Hemisphere (x5.7), Brain - Hypothalamus (x5.7), Brain - Cerebellum (x5.6), and Kidney - Cortex (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of BCRP2 Gene:

BCRP2

SOURCE GeneReport for Unigene cluster for BCRP2 Gene:

Hs.745077
genes like me logo Genes that share expression patterns with BCRP2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BCRP2 Gene

Orthologs for BCRP2 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCRP2 Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta CG2112 35
  • 43 (a)
worm
(Caenorhabditis elegans)
Secernentea R11D1.1b 35
  • 29 (a)
Species where no ortholog for BCRP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for BCRP2 Gene

ENSEMBL:
Gene Tree for BCRP2 (if available)
TreeFam:
Gene Tree for BCRP2 (if available)

Paralogs for BCRP2 Gene

No data available for Paralogs for BCRP2 Gene

Variants for BCRP2 Gene

Sequence variations from dbSNP and Humsavar for BCRP2 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000233918 -- 21,106,690(+) T/G intron_variant
rs1000566641 -- 21,105,116(+) G/A/C intron_variant
rs1000834184 -- 21,109,373(+) T/C intron_variant
rs1000835205 -- 21,102,648(+) G/A upstream_transcript_variant
rs1001120327 -- 21,104,793(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for BCRP2 Gene

Variant ID Type Subtype PubMed ID
dgv2439n106 CNV duplication 24896259
dgv4483n100 CNV gain 25217958
dgv4486n100 CNV gain 25217958
dgv7993n54 CNV gain 21841781
dgv7994n54 CNV gain 21841781
esv2678175 CNV deletion 23128226
esv2760719 CNV gain 21179565
esv2763693 CNV gain 21179565
esv28075 CNV gain+loss 19812545
esv3344675 CNV duplication 20981092
esv3349584 CNV duplication 20981092
esv3376127 CNV duplication 20981092
esv3647313 CNV loss 21293372
esv3647314 CNV gain 21293372
esv3893441 CNV gain+loss 25118596
esv3893442 CNV gain 25118596
nsv1056614 CNV loss 25217958
nsv1060055 CNV loss 25217958
nsv1065617 CNV gain 25217958
nsv1151609 CNV duplication 26484159
nsv1152837 CNV duplication 26484159
nsv436864 CNV insertion 17901297
nsv437849 CNV loss 16327808
nsv438327 CNV loss 16468122
nsv469751 CNV gain 16826518
nsv471490 CNV gain 19718026
nsv471595 CNV gain+loss 15918152
nsv523162 CNV loss 19592680
nsv588305 CNV loss 21841781
nsv588306 CNV gain 21841781
nsv588308 CNV loss 21841781
nsv820868 CNV duplication 20802225
nsv834142 CNV gain 17160897
nsv964591 CNV duplication 23825009

Additional Variant Information for BCRP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BCRP2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BCRP2 Gene

Disorders for BCRP2 Gene

Additional Disease Information for BCRP2

No disorders were found for BCRP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BCRP2 Gene

Publications for BCRP2 Gene

  1. Linear order of the four BCR-related loci in 22q11. (PMID: 3267213) Budarf M … Emanuel BS (Genomics 1988) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 3 58

Products for BCRP2 Gene

Sources for BCRP2 Gene

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