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Aliases for BCRP1 Gene

Aliases for BCRP1 Gene

  • Breakpoint Cluster Region Pseudogene 1 2 3 5
  • BCR-1 3

External Ids for BCRP1 Gene

Previous GeneCards Identifiers for BCRP1 Gene

  • GC14U990074
  • GC22M024654
  • GC22M024657
  • GC22M024777
  • GC22M024953
  • GC22M025175
  • GC22M024540
  • GC22M024662
  • GC22M025050
  • GC22M025467
  • GC22M025650
  • GC22M025840
  • GC22M026023
  • GC22M026205

Summaries for BCRP1 Gene

GeneCards Summary for BCRP1 Gene

BCRP1 (Breakpoint Cluster Region Pseudogene 1) is a Pseudogene.

Additional gene information for BCRP1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCRP1 Gene

Genomics for BCRP1 Gene

GeneHancer (GH) Regulatory Elements for BCRP1 Gene

Promoters and enhancers for BCRP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J024264 Enhancer 0.2 Ensembl 650.7 -0.8 -836 0.8 GC22P024416 GC22P024423 PIR49156 GC22P024406 GC22P024276 GC22P024275 BCRP1 POM121L9P RPS10P29 PIRC110
GH22J024200 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 12.2 +58.4 58400 10.7 FOXA2 SIN3A ZNF48 YY1 GTF3C2 TCF12 FOS NFKBIZ RXRA REST SUSD2 MIF-AS1 CABIN1 GGTLC4P POM121L9P BCRP1 RPS10P29 SPECC1L SNRPD3 ENSG00000232545
GH22J024284 Enhancer 0.9 Ensembl ENCODE 12.6 -21.2 -21173 1.2 HDAC1 BCOR MEIS2 PKNOX1 USF1 JUN FEZF1 BATF IRF4 FOSL1 BCRP1 POM121L9P GGTLC4P SPECC1L SPECC1L-ADORA2A LOC105372960
GH22J024213 Enhancer 0.3 dbSUPER 12.2 +48.8 48827 2 PRDM10 SUSD2 CABIN1 GGTLC4P POM121L9P BCRP1 RPS10P29 SPECC1L ENSG00000272578 GGT5
GH22J024258 Enhancer 0.7 Ensembl ENCODE 0.7 +4.4 4364 1.2 CTCF ZNF654 SMC3 RAD21 ZFX PIR47205 POM121L9P BCRP1 GC22P024405 GC22P024412 GC22P024418 PIR33041 PIRC110
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BCRP1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for BCRP1 Gene

Genomic Locations for BCRP1 Gene
chr22:24,257,400-24,263,765
(GRCh38/hg38)
Size:
6,366 bases
Orientation:
Minus strand
chr22:24,653,368-24,659,733
(GRCh37/hg19)

Genomic View for BCRP1 Gene

Genes around BCRP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCRP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCRP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCRP1 Gene

Function for BCRP1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BCRP1 Gene

Localization for BCRP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BCRP1 Gene

Pathways & Interactions for BCRP1 Gene

SuperPathways for BCRP1 Gene

No Data Available

Interacting Proteins for BCRP1 Gene

Gene Ontology (GO) - Biological Process for BCRP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BCRP1 Gene

Drugs & Compounds for BCRP1 Gene

No Compound Related Data Available

Transcripts for BCRP1 Gene

mRNA/cDNA for BCRP1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BCRP1 Gene

No ASD Table

Relevant External Links for BCRP1 Gene

GeneLoc Exon Structure for
BCRP1
ECgene alternative splicing isoforms for
BCRP1

Expression for BCRP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BCRP1 Gene

mRNA differential expression in normal tissues according to GTEx for BCRP1 Gene

This gene is overexpressed in Testis (x16.5).

NURSA nuclear receptor signaling pathways regulating expression of BCRP1 Gene:

BCRP1
genes like me logo Genes that share expression patterns with BCRP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BCRP1 Gene

Orthologs for BCRP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCRP1 Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta CG7380 35
  • 64 (a)
Species where no ortholog for BCRP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for BCRP1 Gene

ENSEMBL:
Gene Tree for BCRP1 (if available)
TreeFam:
Gene Tree for BCRP1 (if available)

Paralogs for BCRP1 Gene

No data available for Paralogs for BCRP1 Gene

Variants for BCRP1 Gene

Additional Variant Information for BCRP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BCRP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for BCRP1 Gene

Disorders for BCRP1 Gene

Additional Disease Information for BCRP1

No disorders were found for BCRP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BCRP1 Gene

Publications for BCRP1 Gene

  1. Linear order of the four BCR-related loci in 22q11. (PMID: 3267213) Budarf M … Emanuel BS (Genomics 1988) 2 3 58
  2. Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. (PMID: 26502886) Ge S … Hu M (Pharmaceutical research 2016) 3 58
  3. The cancer stem cell antigens CD133, BCRP1/ABCG2 and CD117/c-KIT are not associated with prognosis in resected early-stage non-small cell lung cancer. (PMID: 22199321) Herpel E … Gottschling S (Anticancer research 2011) 3 58

Products for BCRP1 Gene

Sources for BCRP1 Gene

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