Aliases for BCL9 Gene
External Ids for BCL9 Gene
Previous GeneCards Identifiers for BCL9 Gene
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
GeneCards Summary for BCL9 Gene
BCL9 (BCL9 Transcription Coactivator) is a Protein Coding gene. Diseases associated with BCL9 include Lymphoma and Leukemia. Among its related pathways are Signaling by Wnt and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include beta-catenin binding. An important paralog of this gene is BCL9L.
UniProtKB/Swiss-Prot Summary for BCL9 Gene
Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity).