Aliases for BCL9 Gene
External Ids for BCL9 Gene
Previous GeneCards Identifiers for BCL9 Gene
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
GeneCards Summary for BCL9 Gene
BCL9 (BCL9 Transcription Coactivator) is a Protein Coding gene. Diseases associated with BCL9 include Lymphoma and Leukemia. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include beta-catenin binding. An important paralog of this gene is BCL9L.
UniProtKB/Swiss-Prot Summary for BCL9 Gene
Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity).