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This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
BCL7C (BAF Chromatin Remodeling Complex Subunit BCL7C) is a Protein Coding gene. Diseases associated with BCL7C include Lymphoma and Burkitt Lymphoma. An important paralog of this gene is BCL7B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006915 | apoptotic process | IEA | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||
SP2: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Dog (Canis familiaris) |
Mammalia | BCL7C 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | BCL7C 30 31 |
|
OneToOne | |
Chimpanzee (Pan troglodytes) |
Mammalia | BCL7C 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Bcl7c 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Bcl7c 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | BCL7C 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | BCL7C 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | BCL7C 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100158618 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | BCL7-like 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | C28H8.1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv35n68 | CNV | loss | 17160897 |
esv28742 | CNV | loss | 19812545 |
nsv1060384 | CNV | gain | 25217958 |
nsv1113781 | CNV | deletion | 24896259 |
nsv457483 | CNV | loss | 19166990 |
nsv507813 | OTHER | sequence alteration | 20534489 |
nsv571820 | CNV | loss | 21841781 |
nsv833189 | CNV | loss | 17160897 |
nsv953802 | CNV | deletion | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
lymphoma |
|
|
burkitt lymphoma |
|
|
small-cell carcinoma of the ovary of hypercalcemic type |
|
|
capgras syndrome |
|
|
autosomal dominant non-syndromic intellectual disability |
|
|