Aliases for BCL7A Gene
External Ids for BCL7A Gene
Previous HGNC Symbols for BCL7A Gene
Previous GeneCards Identifiers for BCL7A Gene
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BCL7A Gene
BCL7A (BAF Chromatin Remodeling Complex Subunit BCL7A) is a Protein Coding gene. Diseases associated with BCL7A include Lymphoma and B-Cell Non-Hodgkin Lymphoma. An important paralog of this gene is BCL7C.