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This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of diff... See more...
Aliases for BCL2L12 Gene
Aliases for BCL2L12 Gene
External Ids for BCL2L12 Gene
- HGNC: 13787
- Entrez Gene: 83596
- Ensembl: ENSG00000126453
- OMIM: 610837
- UniProtKB: Q9HB09
Previous GeneCards Identifiers for BCL2L12 Gene
- GC19P050826
- GC19P050536
- GC19P054844
- GC19P054860
- GC19P050168
- GC19P046545
Summaries for BCL2L12 Gene
-
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneCards Summary for BCL2L12 Gene
BCL2L12 (BCL2 Like 12) is a Protein Coding gene. Diseases associated with BCL2L12 include Autoimmune Lymphoproliferative Syndrome, Type Iii and Laryngeal Benign Neoplasm. Among its related pathways are Regulation of Apoptosis by Parathyroid Hormone-related Protein. Gene Ontology (GO) annotations related to this gene include p53 binding. An important paralog of this gene is BCL2L14.
Additional gene information for BCL2L12 Gene
- HGNC(13787)
- Entrez Gene(83596)
- Ensembl(ENSG00000126453)
- OMIM(610837)
- UniProtKB(Q9HB09)
- Open Targets Platform(ENSG00000126453)
- Monarch Initiative
- Search for BCL2L12 at DataMed
- Search for BCL2L12 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BCL2L12 Gene
Genomics for BCL2L12 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for BCL2L12 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around BCL2L12 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BCL2L12
- Top Transcription factor binding sites by QIAGEN in the BCL2L12 gene promoter:
-
- COUP-TF
- NF-kappaB
- NF-kappaB1
- p300
- p53
- STAT1
Genomic Locations for BCL2L12 Gene
Genomic Locations for BCL2L12 Gene
- chr19:49,664,834-49,673,916
- (GRCh38/hg38)
- Size:
- 9,083 bases
- Orientation:
- Plus strand
- chr19:50,168,399-50,177,173
- (GRCh37/hg19)
- Size:
- 8,775 bases
- Orientation:
- Plus strand
Genomic View for BCL2L12 Gene
Genes around BCL2L12 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
BCL2L12 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BCL2L12 Gene
Proteins for BCL2L12 Gene
-
Protein details for BCL2L12 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HB09-B2L12_HUMAN
- Recommended name:
- Bcl-2-like protein 12
- Protein Accession:
- Q9HB09
- Q3SY11
- Q3SY13
- Q96I96
- Q9HB08
Protein attributes for BCL2L12 Gene
- Size:
- 334 amino acids
- Molecular mass:
- 36821 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Protein Expression for BCL2L12 Gene
Post-translational modifications for BCL2L12 Gene
Other Protein References for BCL2L12 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ BCL2L12 Antibody and Immunotag™ BCL2L12 Polyclonal Antibody
- GeneTex Anti-BCL2L12 antibody
- Novus Biologicals Antibodies for BCL2L12
-
Abcam antibodies for BCL2L12
- Invitrogen Antibodies for BCL2L12 (AFLGC-BCL2L12)
-
Biorbyt antibodies for BCL2L12
- Sino Biological Antibodies for BCL2L12
Protein Products
-
OriGene Purified Proteins for BCL2L12
- Search Origene for MassSpec and Protein Over-expression Lysates for BCL2L12
- Origene Custom Protein Services for BCL2L12
- Sino Biological Recombinant Proteins for BCL2L12
- Browse Sino Biological Cell Lysates
- antibodies-online: Show 5 available BCL2L12 Proteins ranked by validation data
- Compare Top BCL2L12 Proteins
-
Quality Products:
-
Signalway Proteins for BCL2L12
-
Abcam proteins for BCL2L12
No data available for DME Specific Peptides for BCL2L12 Gene
Domains & Families for BCL2L12 Gene
Gene Families for BCL2L12 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for BCL2L12 Gene
- InterPro:
- Blocks:
-
- Apoptosis regulator Bcl-2 protein, BH
- ProtoNet:
Suggested Antigen Peptide Sequences for BCL2L12 Gene
- GenScript: Design optimal peptide antigens:
-
- Bcl-2-related proline-rich protein (B2L12_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9HB09- Family:
-
- Belongs to the Bcl-2 family.
Function for BCL2L12 Gene
Phenotypes From GWAS Catalog for BCL2L12 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002039 | p53 binding | IEA | -- |
Phenotypes for BCL2L12 Gene
- MGI mutant phenotypes for BCL2L12:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for BCL2L12:
Animal Models for BCL2L12 Gene
- MGI Knock Outs for BCL2L12:
-
- Bcl2l12 Bcl2l12<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BCL2L12 - Select products 50% OFF >
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-
Santa Cruz Biotechnology (SCBT) CRISPR for BCL2L12
miRNA for BCL2L12 Gene
- miRTarBase miRNAs that target BCL2L12
-
- hsa-miR-24-3p (MIRT030470)
- hsa-miR-744-5p (MIRT037475)
- hsa-miR-455-3p (MIRT037864)
- hsa-miR-18a-3p (MIRT040770)
- hsa-miR-7-5p (MIRT253100)
- hsa-miR-125a-5p (MIRT253103)
- hsa-miR-890 (MIRT253104)
- hsa-miR-1238-5p (MIRT253105)
- hsa-miR-1207-5p (MIRT253106)
- hsa-miR-548e-5p (MIRT253107)
- hsa-miR-3616-3p (MIRT253112)
- hsa-miR-4632-5p (MIRT253114)
- hsa-miR-4758-5p (MIRT253115)
- hsa-miR-4763-3p (MIRT253116)
- hsa-miR-4436b-3p (MIRT253117)
- hsa-miR-6124 (MIRT253118)
- hsa-miR-6505-5p (MIRT253119)
- hsa-miR-6721-5p (MIRT253120)
- hsa-miR-6735-5p (MIRT253121)
- hsa-miR-6835-3p (MIRT253122)
- hsa-miR-6879-5p (MIRT253123)
- hsa-miR-7843-5p (MIRT253124)
- hsa-miR-8087 (MIRT253127)
- hsa-miR-3978 (MIRT561156)
- hsa-miR-3148 (MIRT561157)
- hsa-miR-4745-5p (MIRT561158)
- hsa-miR-4481 (MIRT561159)
- hsa-miR-6876-5p (MIRT561160)
- hsa-miR-4476 (MIRT561161)
- hsa-miR-1276 (MIRT736950)
- hsa-miR-15a-5p (MIRT737931)
- hsa-miR-15b-5p (MIRT737953)
- hsa-miR-16-5p (MIRT737981)
- hsa-miR-1910-5p (MIRT738466)
- hsa-miR-195-5p (MIRT738620)
- hsa-miR-3670 (MIRT742087)
- hsa-miR-424-5p (MIRT743293)
- hsa-miR-4251 (MIRT743313)
- hsa-miR-4264 (MIRT743490)
- hsa-miR-4303 (MIRT743878)
- hsa-miR-4329 (MIRT744113)
- hsa-miR-4524a-5p (MIRT745865)
- hsa-miR-4524b-5p (MIRT745898)
- hsa-miR-497-5p (MIRT749274)
- hsa-miR-503-5p (MIRT749538)
- hsa-miR-539-5p (MIRT750344)
- hsa-miR-643 (MIRT752734)
- hsa-miR-646 (MIRT752752)
- hsa-miR-6761-5p (MIRT754956)
- hsa-miR-6838-5p (MIRT757275)
- hsa-miR-6854-5p (MIRT757667)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for BCL2L12 - Select products 50% OFF >
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- RC221347
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- RC236295
- RC236465
- RC236692
- RC236885
- RC237057
- RG214730
- RG221347
- RR212858
- RR212858L3
- RR212858L4
- MR201753L3V
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- MR226674L3V
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- RC214730L3V
- RC214730L4V
- RC221347L1V
- RC221347L2V
- RC221347L3V
- RC221347L4V
- RR212858L3V
- RR212858L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BCL2L12
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BCL2L12
Cell Line Products
-
Horizon Cell Lines for BCL2L12
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for BCL2L12 Gene
Localization for BCL2L12 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| extracellular | 2 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| peroxisome | 0 |
- Plasma membrane (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 20837658 |
| GO:0016020 | membrane | HDA | 19946888 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for BCL2L12 Gene
Pathways & Interactions for BCL2L12 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of Apoptosis by Parathyroid Hormone-related Protein | ||
Pathways by source for BCL2L12 Gene
1 BioSystems pathway for BCL2L12 Gene
Interacting Proteins for BCL2L12 Gene
Selected Interacting proteins:
Q9HB09-B2L12_HUMAN
ENSP00000482218
for BCL2L12 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for BCL2L12
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0042981 | regulation of apoptotic process | IEA | -- |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 22262180 |
| GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | IEA | -- |
| GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process | IDA | 22262180 |
Transcripts for BCL2L12 Gene
mRNA/cDNA for BCL2L12 Gene
- 7 REFSEQ mRNAs :
- 65 NCBI additional mRNA sequence :
- 13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000441864 1371 nts (view in UCSC)
- ENST00000246785 1431 nts (view in UCSC)
- ENST00000594157 620 nts (view in UCSC)
- ENST00000598979 893 nts (view in UCSC)
- ENST00000601168 416 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BCL2L12 - Select products 50% OFF >
- * BCL2L12 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for BCL2L12
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BCL2L12
-
Santa Cruz Biotechnology (SCBT) CRISPR for BCL2L12
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BCL2L12
- Browse OriGene Inhibitory RNA Products For BCL2L12
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BCL2L12
Clone Products
- Applied Biological Materials (abm): Clones for BCL2L12 - Select products 50% OFF >
- * BCL2L12 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG201753
- MG226674
- MR201753
- MR201753L3
- MR201753L4
- MR226674
- MR226674L3
- MR226674L4
- RC214730
- RC214730L3
- RC214730L4
- RC221347
- RC221347L1
- RC221347L2
- RC221347L3
- RC221347L4
- RC236295
- RC236465
- RC236692
- RC236885
- RC237057
- RG214730
- RG221347
- RR212858
- RR212858L3
- RR212858L4
- MR201753L3V
- MR201753L4V
- MR226674L3V
- MR226674L4V
- RC214730L3V
- RC214730L4V
- RC221347L1V
- RC221347L2V
- RC221347L3V
- RC221347L4V
- RR212858L3V
- RR212858L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BCL2L12
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BCL2L12
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | |||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||
| SP6: |
Relevant External Links for BCL2L12 Gene
- GeneLoc Exon Structure for
- BCL2L12
Expression for BCL2L12 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Secondary Spermatocyte Seminiferous Tubules
-
Gonad
- Secondary Spermatocyte Seminiferous Tubules
- Eye (Sensory Organs)
-
Thymus (Hematopoietic System)
This gene is overexpressed in Bone (49.8) and Breast (19.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BCL2L12 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BCL2L12
SOURCE GeneReport for Unigene cluster for BCL2L12 Gene:
Hs.289052mRNA Expression by UniProt/SwissProt for BCL2L12 Gene:
Q9HB09-B2L12_HUMAN
Tissue specificity:
Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
Evidence on tissue expression from TISSUES for BCL2L12 Gene
- Liver(4.3)
- Nervous system(2.6)
- Intestine(2.3)
Primer Products
-
OriGene qPCR primer pairs for BCL2L12
-
OriGene qPCR primer pairs and template standards for BCL2L12
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for BCL2L12 Gene
Orthologs for BCL2L12 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | BCL2L12 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | BCL2L12 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | BCL2L12 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Bcl2l12 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Bcl2l12 30 17 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | BCL2L12 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | BCL2L12 31 |
|
OneToOne |
- Species where no ortholog for BCL2L12 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for BCL2L12 Gene
- ENSEMBL:
- Gene Tree for BCL2L12 (if available)
- TreeFam:
- Gene Tree for BCL2L12 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for BCL2L12: view image
Paralogs for BCL2L12 Gene
Pseudogenes.org Pseudogenes for BCL2L12 Gene
Variants for BCL2L12 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BCL2L12 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1057519880 | Likely Pathogenic: Squamous cell carcinoma of the skin; Malignant melanoma of skin | 49,665,875(+) | C/T | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT | |
| rs2060263 | - | p.Gly47Val |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1160655 | CNV | deletion | 26073780 |
| nsv469715 | CNV | gain+loss | 16826518 |
| nsv470150 | CNV | gain | 18288195 |
| nsv817854 | CNV | gain | 17921354 |
| nsv828578 | CNV | loss | 20364138 |
| nsv833864 | CNV | gain | 17160897 |
| nsv833865 | CNV | gain+loss | 17160897 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv9739 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
91.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.82;
58.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BCL2L12 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BCL2L12
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BCL2L12 Gene
Disorders for BCL2L12 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| autoimmune lymphoproliferative syndrome, type iii |
|
|
| laryngeal benign neoplasm |
|
|
| gliosarcoma |
|
|
Search BCL2L12 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for BCL2L12
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for BCL2L12 Gene
Publications for BCL2L12 Gene
- Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family. (PMID: 11401436) Scorilas A … Diamandis EP (Genomics 2001) 3 4 23
- Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer. (PMID: 19903463) Florou D … Scorilas A (Biochemical and biophysical research communications 2010) 3 23
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma. (PMID: 20855536) Kelly JL … Cerhan JR (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
- What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. (PMID: 18769159) Stegh AH … DePinho RA (Cell cycle (Georgetown, Tex.) 2008) 3 23
ExternalLinks
Products for BCL2L12 Gene
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- Browse OriGene Inhibitory RNA Products For BCL2L12
- OriGene qPCR primer pairs for BCL2L12
- OriGene qPCR primer pairs and template standards for BCL2L12
- OriGene CRISPR knockouts for BCL2L12
- MG201753
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- antibodies-online: Show 17 available BCL2L12 Antibodies ranked by validation data
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Sources for BCL2L12 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
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- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
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- (44) Atlas
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- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
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- (89) antibodies-online
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- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
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- (100) DGIdb
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- (104) diseasecard
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- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
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- (159) GeneImprint
- (160) Synthego
- (161) ENA
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- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
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- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB