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BCAS3 (BCAS3 Microtubule Associated Cell Migration Factor) is a Protein Coding gene. Diseases associated with BCAS3 include Transvestism and Fetishism. Among its related pathways are Ectoderm Differentiation. Gene Ontology (GO) annotations related to this gene include chromatin binding and histone binding.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003682 | chromatin binding | IDA | 17505058 |
GO:0005515 | protein binding | IPI | 22300583 |
GO:0008134 | transcription factor binding | IPI | 17505058 |
GO:0010698 | acetyltransferase activator activity | IDA | 17505058 |
GO:0035035 | histone acetyltransferase binding | IPI | 17505058 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 17505058 |
GO:0005737 | cytoplasm | IBA,IDA | 17505058 |
GO:0005856 | cytoskeleton | IEA | -- |
GO:0005881 | cytoplasmic microtubule | ISS | -- |
GO:0031252 | cell leading edge | ISS | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Ectoderm Differentiation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001525 | angiogenesis | IEA | -- |
GO:0007030 | Golgi organization | ISS | -- |
GO:0010595 | positive regulation of endothelial cell migration | ISS | -- |
GO:0031023 | microtubule organizing center organization | ISS | -- |
GO:0034260 | negative regulation of GTPase activity | ISS | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | BCAS3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | BCAS3 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | BCAS3 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | BCAS3 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | BCAS3 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Bcas3 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Bcas3 30 17 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | BCAS3 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | bcas3 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | bcas3 30 31 |
|
OneToOne | |
zgc63764 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001090 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG43154 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | F56C9.10 31 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs2643103 | - | p.Asn87Ser | |||
rs34712615 | - | p.Ile106Val |
Disorder | Aliases | PubMed IDs |
---|---|---|
transvestism |
|
|
fetishism |
|
|
mixed fibrolamellar hepatocellular carcinoma |
|
|
breast cancer |
|