Aliases for BARX2 Gene
External Ids for BARX2 Gene
Previous GeneCards Identifiers for BARX2 Gene
This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008]
GeneCards Summary for BARX2 Gene
BARX2 (BARX Homeobox 2) is a Protein Coding gene. Diseases associated with BARX2 include Jacobsen Syndrome. Among its related pathways are Preimplantation Embryo. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and chromatin binding. An important paralog of this gene is BARX1.
UniProtKB/Swiss-Prot Summary for BARX2 Gene
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia (By similarity).