External Ids for BARX1 Gene
Previous GeneCards Identifiers for BARX1 Gene
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]
GeneCards Summary for BARX1 Gene
BARX1 (BARX Homeobox 1) is a Protein Coding gene. Diseases associated with BARX1 include Gastritis, Familial Giant Hypertrophic and Hard Palate Cancer. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is BARX2.
UniProtKB/Swiss-Prot for BARX1 Gene
Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.