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BARHL2 (BarH Like Homeobox 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific. An important paralog of this gene is BARHL1.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH01J090717 | Promoter/Enhancer | 1.2 | FANTOM5 Ensembl | 656.8 | -1.0 | -977 | 1 | ZNF629 PRDM1 ZIC2 PKNOX1 PATZ1 ZNF501 EZH2 ZNF341 SP2 ZNF639 | BARHL2 ENSG00000287076 lnc-ZNF326-6 RF00104-001 ZNF644 | |
GH01J090957 | Enhancer | 1 | Ensembl ENCODE | 10.7 | -242.4 | -242399 | 9 | CEBPG GATAD2A ATF7 RCOR2 PRDM1 SOX6 FOXJ2 CEBPA SOX13 CEBPB | BARHL2 ZNF644 piR-58852-003 MN308749 lnc-BARHL2-5 | |
GH01J090828 | Enhancer | 0.4 | UCNEbase | 10.9 | -111.7 | -111667 | 0.4 | DACH1 | BARHL2 LINC01763 RF00104-001 LINC02609 ZNF644 | |
GH01J090759 | Enhancer | 0.3 | UCNEbase | 11.7 | -42.4 | -42417 | 0.4 | BARHL2 ENSG00000287076 lnc-ZNF326-6 RF00104-001 ZNF644 | ||
GH01J090965 | Enhancer | 0.3 | Ensembl | 10.7 | -247.9 | -247899 | 0.4 | HLF CTCF | BARHL2 piR-58852-003 MN308749 ZNF644 lnc-BARHL2-5 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IBA | 21873635 |
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IEA,IBA | 21873635 |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA-binding transcription factor activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000790 | nuclear chromatin | ISA | -- |
GO:0005634 | nucleus | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001709 | cell fate determination | IEA | -- |
GO:0001764 | neuron migration | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0006357 | regulation of transcription by RNA polymerase II | IEA,IBA | 21873635 |
GO:0007399 | nervous system development | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | BARHL2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | BARHL2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | BARHL2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Barhl2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Barhl2 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | BARHL2 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | BARHL2 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | barhl2 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | LOC398182 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | barhl2 30 31 |
|
OneToOne | |
Dr.16934 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG11085 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | ceh-30 31 |
|
ManyToMany | |
ceh-31 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
No disorders were found for BARHL2 Gene.