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This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] See more...
Aliases for BANP Gene
Aliases for BANP Gene
External Ids for BANP Gene
- HGNC: 13450
- Entrez Gene: 54971
- Ensembl: ENSG00000172530
- OMIM: 611564
- UniProtKB: Q8N9N5
Previous GeneCards Identifiers for BANP Gene
- GC18M011860
- GC16P089015
- GC16P087725
- GC16P087766
- GC16P086542
- GC16P087984
- GC16P073724
Summaries for BANP Gene
-
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
GeneCards Summary for BANP Gene
BANP (BTG3 Associated Nuclear Protein) is a Protein Coding gene. Diseases associated with BANP include Keratoconus and Brittle Cornea Syndrome 2. Among its related pathways are Gene Expression and Regulation of TP53 Activity. Gene Ontology (GO) annotations related to this gene include p53 binding.
UniProtKB/Swiss-Prot Summary for BANP Gene
-
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Additional gene information for BANP Gene
- HGNC(13450)
- Entrez Gene(54971)
- Ensembl(ENSG00000172530)
- OMIM(611564)
- UniProtKB(Q8N9N5)
- Open Targets Platform(ENSG00000172530)
- Monarch Initiative
- Search for BANP at DataMed
- Search for BANP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BANP Gene
Genomics for BANP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for BANP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around BANP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BANP
- Top Transcription factor binding sites by QIAGEN in the BANP gene promoter:
-
- AP-1
- ATF-2
- c-Jun
- p53
Genomic Locations for BANP Gene
Genomic Locations for BANP Gene
- chr16:87,949,216-88,077,318
- (GRCh38/hg38)
- Size:
- 128,103 bases
- Orientation:
- Plus strand
- chr16:87,982,850-88,110,924
- (GRCh37/hg19)
- Size:
- 128,075 bases
- Orientation:
- Plus strand
Genomic View for BANP Gene
Genes around BANP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.2 by HGNC
- 16q24.2 by Entrez Gene
- 16q24.2 by Ensembl
BANP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BANP Gene
Proteins for BANP Gene
-
Protein details for BANP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N9N5-BANP_HUMAN
- Recommended name:
- Protein BANP
- Protein Accession:
- Q8N9N5
- A8MU25
- A8MX25
- B2RCF7
- B4DNJ9
- F5GZM0
- Q96GJ7
- Q9NWY1
Protein attributes for BANP Gene
- Size:
- 519 amino acids
- Molecular mass:
- 56494 Da
- Quaternary structure:
-
- Interacts with TP53 and CUX1/CDP (By similarity). Interacts with HDAC1. Part of a corepressor complex containing BANP, HDAC1, SIN3A, SIN3B, RBL1 and RBL2.
- SequenceCaution:
-
- Sequence=BAC04296.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Protein Expression for BANP Gene
Post-translational modifications for BANP Gene
Other Protein References for BANP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_005256065.1
- XP_005256066.1
- XP_011521472.1
- XP_011521474.1
- XP_011521476.1
- XP_011521477.1
- XP_011521478.1
- XP_011521479.1
- XP_011521480.1
- XP_011521481.1
- XP_011521482.1
- XP_011521483.1
- XP_011521484.1
- XP_011521485.1
- XP_011521486.1
- XP_016878867.1
- XP_016878868.1
- XP_016878869.1
- XP_016878870.1
- XP_016878871.1
- XP_016878872.1
- XP_024306088.1
- XP_024306089.1
- XP_024306090.1
- XP_024306091.1
- XP_024306092.1
- XP_024306093.1
- XP_024306094.1
- XP_024306095.1
- XP_024306096.1
- XP_024306097.1
- XP_024306098.1
- XP_024306099.1
- XP_024306100.1
- XP_024306101.1
- XP_024306102.1
- NP_001167010.1
- NP_001167011.1
- NP_001167012.1
- NP_001167013.1
- NP_001167014.1
- NP_060339.2
- NP_524576.2
Antibody Products
- LifeSpan BioSciences BANP Antibody
- NSJ Bioreagents BANP Antibody (Mouse Monoclonal)
-
Custom Antibody ServicesOriGene Antibodies for BANP
- Novus Biologicals Antibodies for BANP
-
Abcam antibodies for BANP
- Invitrogen Antibodies for BANP (AFLGC-BANP)
-
Biorbyt antibodies for BANP
-
Boster Bio Antibodies for BANP
-
Custom Antibody ServicesProSci Antibodies for BANP
-
Santa Cruz Biotechnology (SCBT) Antibodies for BANP
- Sino Biological Antibodies for BANP
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for BANP
- Origene Custom Protein Services for BANP
- antibodies-online: Show 4 available BANP Proteins ranked by validation data
- Compare Top BANP Proteins
-
Quality Products:
-
Abcam proteins for BANP
Assay Products
- Novus Biologicals ELISA Kits for BANP
- antibodies-online: Show 24 available BANP Elisa Kits ranked by validation data
- Compare Top BANP Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for BANP
No data available for DME Specific Peptides for BANP Gene
Domains & Families for BANP Gene
Gene Families for BANP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for BANP Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for BANP Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA, FLJ96046, Homo sapiens BTG3 associated nuclear protein (BANP), transcriptvariant 2, mRNA (B2RCF7_HUMAN)
- cDNA FLJ59359, highly similar to Homo sapiens BTG3 associated nuclear protein (BANP), transcript variant 2, mRNA (B4DNJ9_HUMAN)
- Scaffold/matrix-associated region-1-binding protein (BANP_HUMAN)
- BTG3 associated nuclear protein, isoform CRA_a (D3DUN6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N9N5- Family:
-
- Belongs to the BANP/SMAR1 family.
Function for BANP Gene
Molecular function for BANP Gene
- UniProtKB/Swiss-Prot Function:
- Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Phenotypes From GWAS Catalog for BANP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002039 | p53 binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for BANP Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BANP - Select products 50% OFF >
- * BANP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for BANP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BANP
-
Santa Cruz Biotechnology (SCBT) CRISPR for BANP
miRNA for BANP Gene
- miRTarBase miRNAs that target BANP
-
- hsa-miR-320a (MIRT438652)
- hsa-miR-4283 (MIRT487483)
- hsa-miR-25-5p (MIRT487484)
- hsa-miR-423-5p (MIRT487485)
- hsa-miR-3184-5p (MIRT487486)
- hsa-miR-4285 (MIRT487487)
- hsa-miR-6813-5p (MIRT487488)
- hsa-miR-6085 (MIRT487490)
- hsa-miR-1286 (MIRT527617)
- hsa-miR-5681a (MIRT527618)
- hsa-miR-371a-5p (MIRT527619)
- hsa-miR-3619-5p (MIRT527620)
- hsa-miR-761 (MIRT527621)
- hsa-miR-214-3p (MIRT527622)
- hsa-miR-6165 (MIRT527623)
- hsa-miR-888-5p (MIRT527624)
- mmu-miR-5101 (MIRT595050)
- mmu-miR-674-5p (MIRT599647)
- mmu-miR-3473d (MIRT599648)
- mmu-miR-3473c (MIRT599649)
- mmu-miR-1905 (MIRT599650)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BANP
- Browse OriGene Inhibitory RNA Products For BANP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BANP
Clone Products
- Applied Biological Materials (abm): Clones for BANP - Select products 50% OFF >
- * BANP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG208181
- MG227667
- MR208181
- MR208181L3
- MR208181L4
- MR227667
- MR227667L3
- MR227667L4
- MR230295
- MR230308
- RC203448
- RC203448L3
- RC203448L4
- RC212927
- RC212927L3
- RC212927L4
- RC230131
- RC230131L3
- RC230131L4
- RC230180
- RC230180L3
- RC230180L4
- RC230197
- RC230197L3
- RC230197L4
- RC230201
- RC230201L3
- RC230201L4
- RC230218
- RC230218L3
- RC230218L4
- RG203448
- RG212927
- RG230131
- RG230180
- RG230197
- RG230201
- RG230218
- RR206273
- RR206273L3
- RR206273L4
- MR208181L3V
- MR208181L4V
- MR227667L3V
- MR227667L4V
- RC203448L3V
- RC203448L4V
- RC212927L3V
- RC212927L4V
- RC230131L3V
- RC230131L4V
- RC230180L3V
- RC230180L4V
- RC230197L3V
- RC230197L4V
- RC230201L3V
- RC230201L4V
- RC230218L3V
- RC230218L4V
- RR206273L3V
- RR206273L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BANP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BANP
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BANP Gene
Localization for BANP Gene
Subcellular locations from UniProtKB/Swiss-Prot for BANP Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Nuclear bodies (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for BANP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of TP53 Activity | ||
| 2 | Gene Expression |
.48
|
|
Pathways by source for BANP Gene
Interacting Proteins for BANP Gene
Selected Interacting proteins:
Q8N9N5-BANP_HUMAN
ENSP00000376902
for BANP Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for BANP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0034504 | protein localization to nucleus | IBA | 21873635 |
| GO:0042177 | negative regulation of protein catabolic process | IBA | 21873635 |
No data available for SIGNOR curated interactions for BANP Gene
Transcripts for BANP Gene
mRNA/cDNA for BANP Gene
- 7 REFSEQ mRNAs :
- 20 NCBI additional mRNA sequence :
- 27 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000569400 802 nts (view in UCSC)
- ENST00000423252 644 nts (view in UCSC)
- ENST00000488074 759 nts (view in UCSC)
- ENST00000439677 736 nts (view in UCSC)
- ENST00000454563 558 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for BANP - Select products 50% OFF >
- * BANP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for BANP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for BANP
-
Santa Cruz Biotechnology (SCBT) CRISPR for BANP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BANP
- Browse OriGene Inhibitory RNA Products For BANP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BANP
Clone Products
- Applied Biological Materials (abm): Clones for BANP - Select products 50% OFF >
- * BANP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG208181
- MG227667
- MR208181
- MR208181L3
- MR208181L4
- MR227667
- MR227667L3
- MR227667L4
- MR230295
- MR230308
- RC203448
- RC203448L3
- RC203448L4
- RC212927
- RC212927L3
- RC212927L4
- RC230131
- RC230131L3
- RC230131L4
- RC230180
- RC230180L3
- RC230180L4
- RC230197
- RC230197L3
- RC230197L4
- RC230201
- RC230201L3
- RC230201L4
- RC230218
- RC230218L3
- RC230218L4
- RG203448
- RG212927
- RG230131
- RG230180
- RG230197
- RG230201
- RG230218
- RR206273
- RR206273L3
- RR206273L4
- MR208181L3V
- MR208181L4V
- MR227667L3V
- MR227667L4V
- RC203448L3V
- RC203448L4V
- RC212927L3V
- RC212927L4V
- RC230131L3V
- RC230131L4V
- RC230180L3V
- RC230180L4V
- RC230197L3V
- RC230197L4V
- RC230201L3V
- RC230201L4V
- RC230218L3V
- RC230218L4V
- RR206273L3V
- RR206273L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for BANP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for BANP
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - |
| ExUns: | 17 | ^ | 18 |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: | |||
| SP11: |
Relevant External Links for BANP Gene
- GeneLoc Exon Structure for
- BANP
Expression for BANP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
This gene is overexpressed in Retina (15.2), Blymphocyte (15.0), NK cells (12.6), Testis (6.9), CD8 Tcells (6.8), and Ovary (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BANP Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BANP
SOURCE GeneReport for Unigene cluster for BANP Gene:
Hs.461705mRNA Expression by UniProt/SwissProt for BANP Gene:
Q8N9N5-BANP_HUMAN
Tissue specificity:
Down-regulated in breast cancer cell lines.
Evidence on tissue expression from TISSUES for BANP Gene
- Blood(4.4)
- Liver(4.4)
- Muscle(4.2)
- Nervous system(3.5)
Primer Products
-
OriGene qPCR primer pairs for BANP
-
OriGene qPCR primer pairs and template standards for BANP
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for BANP Gene
Orthologs for BANP Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | BANP 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Banp 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | BANP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | BANP 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Banp 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | BANP 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | BANP 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | BANP 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | BANP 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | banp 30 |
|
||
| MGC76079 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16198 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | banp 30 31 |
|
OneToOne |
- Species where no ortholog for BANP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for BANP Gene
- ENSEMBL:
- Gene Tree for BANP (if available)
- TreeFam:
- Gene Tree for BANP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for BANP: view image
Paralogs for BANP Gene
(1) SIMAP similar genes for BANP Gene using alignment to 11 proteins:
- BANP_HUMAN
- C9J811_HUMAN
- C9JF73_HUMAN
- C9JGM9_HUMAN
- C9JLS0_HUMAN
- C9JLT2_HUMAN
- C9JTM8_HUMAN
- C9JYB6_HUMAN
- D3DUN6_HUMAN
- E9PIP2_HUMAN
- E9PJI6_HUMAN
Pseudogenes.org Pseudogenes for BANP Gene
No data available for Paralogs for BANP Gene
Variants for BANP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BANP Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 756317 | Benign: not provided | 88,027,562(+) | G/A | SYNONYMOUS_VARIANT | |
| rs1555586650 | Uncertain Significance: Ependymoma | 88,018,464(+) | A/G | MISSENSE_VARIANT |
Residual Variation Intolerance Score:
30% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.57;
72.26% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BANP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BANP
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BANP Gene
Disorders for BANP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| keratoconus |
|
|
| brittle cornea syndrome 2 |
|
|
| breast cancer |
|
|
Search BANP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for BANP
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for BANP Gene
Publications for BANP Gene
- Identification and molecular analysis of BANP. (PMID: 10940556) Birot A … Rouault J (Gene 2000) 2 3 4 23
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. (PMID: 20719862) Vitart V … Wright A (Human molecular genetics 2010) 3 41
- SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription. (PMID: 19303885) Pavithra L … Chattopadhyay S (Journal of molecular biology 2009) 3 23
- Loci at chromosomes 13, 19 and 20 influence age at natural menopause. (PMID: 19448619) Stolk L … Uitterlinden AG (Nature genetics 2009) 3 41
ExternalLinks
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Sources for BANP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6)