This gene produces a long non-coding RNA that plays a role in tumor progression and epithelial to mesenchymal transition. This transcript acts through the MAP kinase signaling pathway. [provided by RefSeq, Dec 2017] See more...

Aliases for BANCR Gene

Data sources for BANCR Gene:

Subcategory (RNA class) for BANCR Gene

lncRNA

Aliases for BANCR Gene

External Ids for BANCR Gene

Previous GeneCards Identifiers for BANCR Gene

  • GC00U934042
  • GC09U901795

Summaries for BANCR Gene

Entrez Gene Summary for BANCR Gene

  • This gene produces a long non-coding RNA that plays a role in tumor progression and epithelial to mesenchymal transition. This transcript acts through the MAP kinase signaling pathway. [provided by RefSeq, Dec 2017]

GeneCards Summary for BANCR Gene

BANCR (BRAF-Activated Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with BANCR include Esophagitis, Eosinophilic, 1 and Gastrointestinal System Cancer.

Additional gene information for BANCR Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BANCR Gene

Genomics for BANCR Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for BANCR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J069306 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 250.7 +3.0 3001 2.9 ZNF395 YY1 NFE2 SP1 TAF1 CAVIN1 RFX1 ESRRA HDAC8 PYGO2 BANCR HSALNG0071735 SMC5 PTAR1 PABIR1 ENSG00000268364 PGM5-AS1 ENSG00000233178 FAM189A2 HSALNG0071733
GH09J069311 Promoter 0.3 EPDnew 250.7 0.0 0 0.1 BANCR HSALNG0071735 FAM189A2 TJP2
GH09J069296 Enhancer 0.6 Ensembl ENCODE 0.4 +14.3 14340 1.6 ZNF512B MAFG ZNF366 FAM189A2 BANCR HSALNG0071735 HSALNG0071733 TJP2
GH09J069318 Enhancer 0.4 Ensembl CraniofacialAtlas 0.4 -8.6 -8561 2.2 PRDM4 FAM189A2 BANCR TJP2
GH09J069300 Enhancer 0.2 Ensembl 0.4 +10.7 10739 0.8 FAM189A2 HSALNG0071735 BANCR HSALNG0071733 TJP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BANCR on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for BANCR Gene

Latest Assembly
chr9:69,296,677-69,311,140
(GRCh38/hg38)
Size:
14,464 bases
Orientation:
Minus strand

Previous Assembly
chr9:71,911,597-71,921,972
(GRCh37/hg19 by Entrez Gene)
Size:
10,376 bases
Orientation:
Minus strand

Genomic View for BANCR Gene

Genes around BANCR on UCSC Golden Path with GeneCards custom track
BANCR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
BANCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BANCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BANCR Gene

Proteins for BANCR Gene

Post-translational modifications for BANCR Gene

No Post-translational modifications

No data available for DME Specific Peptides for BANCR Gene

Domains & Families for BANCR Gene

Gene Families for BANCR Gene

genes like me logo Genes that share domains with BANCR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for BANCR Gene

Function for BANCR Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BANCR Gene

Localization for BANCR Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BANCR gene
Compartment Confidence
cytoskeleton 2
plasma membrane 1
extracellular 1
mitochondrion 1
nucleus 1
cytosol 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BANCR Gene

Pathways & Interactions for BANCR Gene

PathCards logo

SuperPathways for BANCR Gene

No Data Available

Gene Ontology (GO) - Biological Process for BANCR Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for BANCR Gene

Drugs & Compounds for BANCR Gene

No Compound Related Data Available

Transcripts for BANCR Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for BANCR Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000D63DE1_9606 lncRNA 754 2

Ensembl: ENST00000624238 (view in UCSC) ,

LNCipedia: BANCR:7,

URS0000D65654_9606 lncRNA 562 2

Ensembl: ENST00000625062 (view in UCSC) ,

LNCipedia: BANCR:6,

URS0000759AA6_9606 lncRNA 675 1

RefSeq: NR_047671,

URS00008B443D_9606 lncRNA 567 3

LncBook: HSALNT0149911,

LNCipedia: BANCR:2,

NONCODE: NONHSAT131776.2,

URS00007C88F0_9606 lncRNA 473 3

LncBook: HSALNT0149912,

LNCipedia: BANCR:5,

NONCODE: NONHSAT220799.1,

BANCR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for BANCR Gene

8 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for BANCR Gene

No ASD Table

Relevant External Links for BANCR Gene

GeneLoc Exon Structure for
BANCR

Expression for BANCR Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BANCR

SOURCE GeneReport for Unigene cluster for BANCR Gene:

Hs.49768
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BANCR Gene

Orthologs for BANCR Gene

Evolution for BANCR Gene

ENSEMBL:
Gene Tree for BANCR (if available)
TreeFam:
Gene Tree for BANCR (if available)

No data available for Orthologs for BANCR Gene

Paralogs for BANCR Gene

No data available for Paralogs for BANCR Gene

Variants for BANCR Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for BANCR Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for BANCR Gene

Variant ID Type Subtype PubMed ID
dgv7665n100 CNV gain 25217958
nsv614548 CNV gain 21841781
nsv831610 CNV gain 17160897

Additional Variant Information for BANCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BANCR

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for BANCR Gene

Disorders for BANCR Gene

MalaCards: The human disease database

(13) MalaCards diseases for BANCR Gene - From: LNC, COP, and GCD

Disorder Aliases PubMed IDs
esophagitis, eosinophilic, 1
  • eoe1
gastrointestinal system cancer
  • digestive system cancer
esophagus squamous cell carcinoma
  • oesophagus squamous cell carcinoma
retinoblastoma
  • rb1
gastric adenocarcinoma
  • adenocarcinoma of stomach
- elite association - COSMIC cancer census association via MalaCards
Search BANCR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for BANCR

genes like me logo Genes that share disorders with BANCR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BANCR Gene

Publications for BANCR Gene

  1. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition. (PMID: 24655544) Sun M … Wang ZX (Molecular cancer 2014) 2 3 74
  2. BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration. (PMID: 22581800) Flockhart RJ … Khavari PA (Genome research 2012) 2 3 74
  3. BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis. (PMID: 28009984) Fan YH … Zhu XG (Oncotarget 2017) 3 74
  4. BRAF-activated LncRNA functions as a tumor suppressor in papillary thyroid cancer. (PMID: 27462868) Liao T … Ji QH (Oncotarget 2017) 3 74
  5. Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells. (PMID: 29085476) Li J … He R (Oncology letters 2017) 3 74

Products for BANCR Gene

Sources for BANCR Gene