This gene produces a long non-coding RNA that plays a role in tumor progression and epithelial to mesenchymal transition. This transcript acts through the MAP kinase signaling pathway. [provided by RefSeq, Dec 2017] See more...

Aliases for BANCR Gene

Subcategory (RNA class) for BANCR Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for BANCR Gene

  • BRAF-Activated Non-Protein Coding RNA 2 3 5
  • BANCR 2 168
  • HSALNG0071734 167
  • NONHSAG052510 92
  • LINC00586 3

External Ids for BANCR Gene

Previous GeneCards Identifiers for BANCR Gene

  • GC00U934042
  • GC09U901795

Summaries for BANCR Gene

Entrez Gene Summary for BANCR Gene

  • This gene produces a long non-coding RNA that plays a role in tumor progression and epithelial to mesenchymal transition. This transcript acts through the MAP kinase signaling pathway. [provided by RefSeq, Dec 2017]

GeneCards Summary for BANCR Gene

BANCR (BRAF-Activated Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with BANCR include Esophagitis, Eosinophilic, 1 and Retinoblastoma.

Additional gene information for BANCR Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BANCR Gene

Genomics for BANCR Gene

GeneHancer (GH) Regulatory Elements for BANCR Gene

Promoters and enhancers for BANCR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J069306 Enhancer 0.9 Ensembl ENCODE 0.7 +3.0 2972 2.9 USF1 TEAD4 POLR2A HDAC2 YY1 NANOG GTF2A2 POLR2H TCF12 NFE2 FAM189A2 BANCR piR-57460-678
GH09J069296 Enhancer 0.5 Ensembl ENCODE 0.4 +14.7 14670 0.9 ZNF512B ZNF366 FAM189A2 BANCR piR-57460-678
GH09J069318 Enhancer 0.4 Ensembl CraniofacialAtlas 0.4 -8.6 -8590 2.2 PRDM4 FAM189A2 BANCR
GH09J069297 Enhancer 0.4 Ensembl 0.4 +13.6 13610 1 ZNF316 MAFF MAFK MAFG EMSY FAM189A2 BANCR piR-57460-678
GH09J069283 Enhancer 0.6 Ensembl ENCODE 0.3 +27.6 27610 1 HDAC2 NANOG EZH2 FAM189A2 piR-57460-678 BANCR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BANCR on UCSC Golden Path with GeneCards custom track

Genomic Locations for BANCR Gene

Genomic Locations for BANCR Gene
chr9:69,296,677-69,311,111
(GRCh38/hg38)
Size:
14,435 bases
Orientation:
Minus strand

Genomic View for BANCR Gene

Genes around BANCR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BANCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BANCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BANCR Gene

Proteins for BANCR Gene

Post-translational modifications for BANCR Gene

No Post-translational modifications

No data available for DME Specific Peptides for BANCR Gene

Domains & Families for BANCR Gene

Gene Families for BANCR Gene

genes like me logo Genes that share domains with BANCR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for BANCR Gene

Function for BANCR Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BANCR Gene

Localization for BANCR Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BANCR gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BANCR Gene

Pathways & Interactions for BANCR Gene

PathCards logo

SuperPathways for BANCR Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for BANCR Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for BANCR Gene

Drugs & Compounds for BANCR Gene

No Compound Related Data Available

Transcripts for BANCR Gene

mRNA/cDNA for BANCR Gene

10 RNACentral transcripts :
1 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
4 NONCODE transcripts :
3 LncBook transcripts :
7 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for BANCR Gene

No ASD Table

Relevant External Links for BANCR Gene

GeneLoc Exon Structure for
BANCR

Expression for BANCR Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BANCR

SOURCE GeneReport for Unigene cluster for BANCR Gene:

Hs.49768
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BANCR Gene

Orthologs for BANCR Gene

Evolution for BANCR Gene

ENSEMBL:
Gene Tree for BANCR (if available)
TreeFam:
Gene Tree for BANCR (if available)

No data available for Orthologs for BANCR Gene

Paralogs for BANCR Gene

No data available for Paralogs for BANCR Gene

Variants for BANCR Gene

Additional dbSNP identifiers (rs#s) for BANCR Gene

Structural Variations from Database of Genomic Variants (DGV) for BANCR Gene

Variant ID Type Subtype PubMed ID
dgv7665n100 CNV gain 25217958
nsv614548 CNV gain 21841781
nsv831610 CNV gain 17160897

Additional Variant Information for BANCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BANCR

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for BANCR Gene

Disorders for BANCR Gene

MalaCards: The human disease database

(13) MalaCards diseases for BANCR Gene - From: LncRNADisease, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search BANCR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for BANCR

genes like me logo Genes that share disorders with BANCR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BANCR Gene

Publications for BANCR Gene

  1. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition. (PMID: 24655544) Sun M … Wang ZX (Molecular cancer 2014) 2 3 54
  2. BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration. (PMID: 22581800) Flockhart RJ … Khavari PA (Genome research 2012) 2 3 54
  3. Epigenetics. Going places with BANCR. (PMID: 22673151) McCarthy N (Nature reviews. Cancer 2012) 2 3 54
  4. Long Non-Coding RNA BANCR Is Overexpressed in Patients with Diabetic Retinopathy and Promotes Apoptosis of Retinal Pigment Epithelial Cells. (PMID: 30996220) Yin L … Zhang D (Medical science monitor : international medical journal of experimental and clinical research 2019) 3 54
  5. LncRNA BANCR participates in polycystic ovary syndrome by promoting cell apoptosis. (PMID: 30592281) Yang R … Deng A (Molecular medicine reports 2019) 3 54

Products for BANCR Gene

Sources for BANCR Gene