Aliases for BAGE3 Gene

Aliases for BAGE3 Gene

  • BAGE Family Member 3 2 3
  • CT2.3 2 3 4
  • Cancer/Testis Antigen Family 2, Member 3 2 3
  • Cancer/Testis Antigen 2.3 3 4
  • B Melanoma Antigen 3 3 4
  • B Melanoma Antigen Family, Member 3 2
  • B Melanoma Antigen Family Member 3 3

External Ids for BAGE3 Gene

Previous GeneCards Identifiers for BAGE3 Gene

  • GC00U991012
  • GC21M010071
  • GC21M010044
  • GC21M010042
  • GC21M010997

Summaries for BAGE3 Gene

GeneCards Summary for BAGE3 Gene

BAGE3 (BAGE Family Member 3) is a Protein Coding gene. Diseases associated with BAGE3 include Melanoma.

UniProtKB/Swiss-Prot Summary for BAGE3 Gene

Additional gene information for BAGE3 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BAGE3 Gene

Genomics for BAGE3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BAGE3

Top Transcription factor binding sites by QIAGEN in the BAGE3 gene promoter:
  • AML1a
  • FOXO3
  • FOXO3a
  • FOXO3b
  • GR
  • GR-alpha
  • GR-beta
  • Nkx6-1
  • Pax-5
  • RP58

Genomic Locations for BAGE3 Gene

Genomic Locations for BAGE3 Gene
Unknown strand

Genomic View for BAGE3 Gene

Cytogenetic band:
GeneLoc Logo Gene Density

No data available for RefSeq DNA sequence for BAGE3 Gene

Proteins for BAGE3 Gene

  • Protein details for BAGE3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    B melanoma antigen 3
    Protein Accession:

    Protein attributes for BAGE3 Gene

    109 amino acids
    Molecular mass:
    12112 Da
    Quaternary structure:
    No Data Available
    • The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.

neXtProt entry for BAGE3 Gene

Post-translational modifications for BAGE3 Gene

No Post-translational modifications

Other Protein References for BAGE3 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for BAGE3 Gene

Domains & Families for BAGE3 Gene

Gene Families for BAGE3 Gene


Protein Domains for BAGE3 Gene

  • B melanoma antigen

Suggested Antigen Peptide Sequences for BAGE3 Gene

GenScript: Design optimal peptide antigens:
  • Cancer/testis antigen 2.3 (BAGE3_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BAGE family.
  • Belongs to the BAGE family.
genes like me logo Genes that share domains with BAGE3: view

Function for BAGE3 Gene

Molecular function for BAGE3 Gene

UniProtKB/Swiss-Prot Function:
Unknown. Candidate gene encoding tumor antigens.
genes like me logo Genes that share phenotypes with BAGE3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BAGE3

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BAGE3 Gene

Localization for BAGE3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BAGE3 Gene


Gene Ontology (GO) - Cellular Components for BAGE3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with BAGE3: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for BAGE3 Gene

Pathways & Interactions for BAGE3 Gene

PathCards logo

SuperPathways for BAGE3 Gene

No Data Available

Interacting Proteins for BAGE3 Gene

Gene Ontology (GO) - Biological Process for BAGE3 Gene


No data available for Pathways by source and SIGNOR curated interactions for BAGE3 Gene

Drugs & Compounds for BAGE3 Gene

No Compound Related Data Available

Transcripts for BAGE3 Gene

mRNA/cDNA for BAGE3 Gene

2 NCBI additional mRNA sequence :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BAGE3

Alternative Splicing Database (ASD) splice patterns (SP) for BAGE3 Gene

No ASD Table

Expression for BAGE3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BAGE3

mRNA Expression by UniProt/SwissProt for BAGE3 Gene:

Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BAGE3 Gene

Orthologs for BAGE3 Gene

No data available for Orthologs and Evolution for BAGE3 Gene

Paralogs for BAGE3 Gene

(4) SIMAP similar genes for BAGE3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BAGE3: view

No data available for Paralogs for BAGE3 Gene

Variants for BAGE3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BAGE3 Gene

SNP ID Clinical significance and condition Chr 21 pos Variation AA Info Type
rs2740327 - p.Arg95Thr
rs9808647 - p.Gln106Arg

Structural Variations from Database of Genomic Variants (DGV) for BAGE3 Gene

Variant ID Type Subtype PubMed ID
dgv2349n106 CNV duplication 24896259
dgv2350n106 CNV deletion 24896259
dgv2351n106 CNV deletion 24896259
dgv2352n106 CNV deletion 24896259
dgv2353n106 CNV deletion 24896259
dgv2354n106 CNV deletion 24896259
dgv2468e59 CNV duplication 20981092
dgv4353n100 CNV loss 25217958
dgv4354n100 CNV gain+loss 25217958
dgv4355n100 CNV gain 25217958
dgv4356n100 CNV loss 25217958
dgv4358n100 CNV gain 25217958
dgv4363n100 CNV loss 25217958
dgv4367n100 CNV gain 25217958
dgv4368n100 CNV gain+loss 25217958
dgv4369n100 CNV gain 25217958
dgv4370n100 CNV loss 25217958
dgv4371n100 CNV gain 25217958
dgv4372n100 CNV loss 25217958
dgv4373n100 CNV gain+loss 25217958
dgv712n67 CNV gain 20364138
dgv73n16 CNV deletion 17901297
dgv7728n54 CNV gain 21841781
dgv7729n54 CNV gain 21841781
dgv7743n54 CNV gain 21841781
esv1000174 CNV deletion 20482838
esv1001067 CNV insertion 20482838
esv1002199 CNV deletion 20482838
esv1008267 CNV deletion 20482838
esv1008615 CNV deletion 20482838
esv2474693 CNV deletion 19546169
esv2563009 CNV deletion 19546169
esv2661615 CNV deletion 23128226
esv2675165 CNV deletion 23128226
esv2758808 CNV gain+loss 17122850
esv2760704 CNV gain 21179565
esv2763681 CNV gain+loss 21179565
esv28756 CNV gain+loss 19812545
esv29976 CNV gain 17803354
esv3057124 CNV deletion 24192839
esv32564 CNV gain+loss 17666407
esv3412511 CNV insertion 20981092
esv3557431 CNV deletion 23714750
esv3557434 CNV deletion 23714750
esv3646371 CNV loss 21293372
esv7291 CNV loss 19470904
esv9537 CNV loss 19470904
esv987944 CNV deletion 20482838
esv991443 OTHER inversion 20482838
esv999403 CNV deletion 20482838
esv999554 CNV insertion 20482838
nsv1057510 CNV loss 25217958
nsv1059291 CNV loss 25217958
nsv1059477 CNV gain 25217958
nsv1060052 CNV loss 25217958
nsv1064391 CNV loss 25217958
nsv1064913 CNV gain 25217958
nsv1071405 CNV deletion 25765185
nsv1071408 CNV deletion 25765185
nsv1071737 CNV deletion 25765185
nsv1071738 CNV deletion 25765185
nsv1071739 CNV deletion 25765185
nsv1071740 CNV deletion 25765185
nsv1071741 CNV deletion 25765185
nsv1072155 CNV deletion 25765185
nsv1072156 CNV deletion 25765185
nsv1072757 CNV deletion 25765185
nsv1073108 CNV deletion 25765185
nsv1073109 CNV deletion 25765185
nsv1073110 CNV deletion 25765185
nsv1073111 CNV deletion 25765185
nsv1078497 CNV duplication 25765185
nsv1109407 CNV deletion 24896259
nsv1114259 CNV deletion 24896259
nsv1116897 CNV deletion 24896259
nsv1123523 CNV deletion 24896259
nsv1123524 CNV deletion 24896259
nsv1123525 CNV deletion 24896259
nsv1136589 CNV deletion 24896259
nsv1136590 CNV deletion 24896259
nsv1136592 CNV deletion 24896259
nsv1136593 CNV deletion 24896259
nsv1138994 CNV deletion 24896259
nsv1138995 CNV deletion 24896259
nsv1138996 CNV deletion 24896259
nsv1138997 CNV deletion 24896259
nsv1143010 CNV tandem duplication 24896259
nsv1150038 CNV deletion 26484159
nsv1151660 CNV duplication 26484159
nsv3451 CNV insertion 18451855
nsv428382 CNV gain+loss 18775914
nsv435743 CNV deletion 17901297
nsv436329 CNV deletion 17901297
nsv436336 CNV deletion 17901297
nsv437841 CNV loss 16327808
nsv469643 CNV loss 16826518
nsv471421 CNV gain 19718026
nsv498974 CNV loss 21111241
nsv512628 CNV loss 21212237
nsv512629 CNV loss 21212237
nsv512630 CNV loss 21212237
nsv586978 CNV gain 21841781
nsv586979 CNV loss 21841781
nsv586980 CNV loss 21841781
nsv819478 CNV gain 19587683
nsv820736 CNV duplication 20802225
nsv828817 CNV gain 20364138
nsv828818 CNV gain 20364138
nsv834041 CNV gain 17160897
nsv953331 CNV duplication 24416366
nsv953332 CNV duplication 24416366
nsv954302 CNV deletion 24416366
nsv956736 CNV deletion 24416366
nsv964472 CNV duplication 23825009
nsv964473 CNV duplication 23825009
nsv965963 CNV duplication 23825009
nsv965965 CNV duplication 23825009
nsv965987 CNV duplication 23825009
nsv979515 CNV duplication 23825009
nsv9838 CNV gain+loss 18304495

Additional Variant Information for BAGE3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Additional dbSNP identifiers (rs#s) and Variation tolerance for BAGE3 Gene

Disorders for BAGE3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for BAGE3 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • malignant melanoma
- elite association - COSMIC cancer census association via MalaCards
Search BAGE3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for BAGE3

genes like me logo Genes that share disorders with BAGE3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BAGE3 Gene

Publications for BAGE3 Gene

  1. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M … De Sario A (European journal of human genetics : EJHG 2002) 2 3 4
  2. BAGE genes generated by juxtacentromeric reshuffling in the Hominidae lineage are under selective pressure. (PMID: 12676563) Ruault M … De Sario A (Genomics 2003) 3 4
  3. The diploid genome sequence of an individual human. (PMID: 17803354) Levy S … Venter JC (PLoS biology 2007) 3
  4. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. (PMID: 16009131) Carroll JS … Brown M (Cell 2005) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for BAGE3 Gene

Sources for BAGE3 Gene