Aliases for B4GALNT3 Gene
External Ids for B4GALNT3 Gene
Previous GeneCards Identifiers for B4GALNT3 Gene
B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]
GeneCards Summary for B4GALNT3 Gene
B4GALNT3 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 3) is a Protein Coding gene. Among its related pathways are Metabolism and N-Glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include acetylgalactosaminyltransferase activity and N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT4.
UniProtKB/Swiss-Prot Summary for B4GALNT3 Gene
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa.