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B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008] See more...
Aliases for B4GALNT3 Gene
Aliases for B4GALNT3 Gene
External Ids for B4GALNT3 Gene
- HGNC: 24137
- Entrez Gene: 283358
- Ensembl: ENSG00000139044
- OMIM: 612220
- UniProtKB: Q6L9W6
Previous GeneCards Identifiers for B4GALNT3 Gene
- GC12P000440
- GC12P000569
Summaries for B4GALNT3 Gene
-
B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]
GeneCards Summary for B4GALNT3 Gene
B4GALNT3 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 3) is a Protein Coding gene. Diseases associated with B4GALNT3 include Epithelial Basement Membrane Dystrophy. Among its related pathways are Metabolism and N-Glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include acetylgalactosaminyltransferase activity and N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT4.
UniProtKB/Swiss-Prot Summary for B4GALNT3 Gene
-
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa.
Additional gene information for B4GALNT3 Gene
- HGNC(24137)
- Entrez Gene(283358)
- Ensembl(ENSG00000139044)
- OMIM(612220)
- UniProtKB(Q6L9W6)
- Open Targets Platform(ENSG00000139044)
- Search for B4GALNT3 at DataMed
- Search for B4GALNT3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for B4GALNT3 Gene
Genomics for B4GALNT3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for B4GALNT3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around B4GALNT3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for B4GALNT3
- Top Transcription factor binding sites by QIAGEN in the B4GALNT3 gene promoter:
-
- aMEF-2
- Bach1
- Evi-1
- MEF-2
- MEF-2A
- NCX
- Pax-5
- POU2F1
- POU2F1a
- SEF-1 (1)
Genomic Locations for B4GALNT3 Gene
Genomic Locations for B4GALNT3 Gene
- chr12:459,939-563,509
- (GRCh38/hg38)
- Size:
- 103,571 bases
- Orientation:
- Plus strand
- chr12:569,530-672,675
- (GRCh37/hg19)
- Size:
- 103,146 bases
- Orientation:
- Plus strand
Genomic View for B4GALNT3 Gene
Genes around B4GALNT3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.33 by HGNC
- 12p13.33 by Entrez Gene
- 12p13.33 by Ensembl
B4GALNT3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for B4GALNT3 Gene
Proteins for B4GALNT3 Gene
-
Protein details for B4GALNT3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6L9W6-B4GN3_HUMAN
- Recommended name:
- Beta-1,4-N-acetylgalactosaminyltransferase 3
- Protein Accession:
- Q6L9W6
- Q6ZNC1
- Q8N7T6
Protein attributes for B4GALNT3 Gene
- Size:
- 998 amino acids
- Molecular mass:
- 114975 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAC05141.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAD18454.1; Type=Miscellaneous discrepancy; Note=Probable intron retention.; Evidence={ECO:0000305};
Protein Expression for B4GALNT3 Gene
Post-translational modifications for B4GALNT3 Gene
Other Protein References for B4GALNT3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-B4GALNT3 monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for B4GALNT3
- Novus Biologicals Antibodies for B4GALNT3
-
Abcam antibodies for B4GALNT3
- Invitrogen Antibodies for B4GALNT3 (AFLGC-B4GALNT3)
- antibodies-online: Show 10 available B4GALNT3 Antibodies ranked by validation data
- Sino Biological Antibodies for B4GALNT3
Protein Products
-
OriGene Purified Proteins for B4GALNT3
- Search Origene for MassSpec and Protein Over-expression Lysates for B4GALNT3
- Origene Custom Protein Services for B4GALNT3
- Novus Biologicals proteins for B4GALNT3
No data available for DME Specific Peptides for B4GALNT3 Gene
Domains & Families for B4GALNT3 Gene
Gene Families for B4GALNT3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for B4GALNT3 Gene
- InterPro:
- Blocks:
-
- PA14
- ProtoNet:
Suggested Antigen Peptide Sequences for B4GALNT3 Gene
- GenScript: Design optimal peptide antigens:
-
- Beta-1,4-N-acetylgalactosaminyltransferase III (B4GN3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q6L9W6UniProtKB/Swiss-Prot:
B4GN3_HUMAN :- Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
- Family:
-
- Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
Function for B4GALNT3 Gene
Molecular function for B4GALNT3 Gene
- UniProtKB/Swiss-Prot Function:
- Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP; Xref=Rhea:RHEA:20493, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:61631, ChEBI:CHEBI:67138, ChEBI:CHEBI:138027; EC=2.4.1.244; Evidence={ECO:0000269|PubMed:12966086};.
Enzyme Numbers (IUBMB) for B4GALNT3 Gene
Phenotypes From GWAS Catalog for B4GALNT3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008376 | acetylgalactosaminyltransferase activity | IDA | 12966086 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity | IEA | -- |
Phenotypes for B4GALNT3 Gene
- MGI mutant phenotypes for B4GALNT3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for B4GALNT3:
Animal Models for B4GALNT3 Gene
- MGI Knock Outs for B4GALNT3:
-
- B4galnt3 B4galnt3<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for B4GALNT3 - Select products 50% OFF >
- * B4GALNT3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for B4GALNT3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for B4GALNT3
-
Santa Cruz Biotechnology (SCBT) CRISPR for B4GALNT3
miRNA for B4GALNT3 Gene
- miRTarBase miRNAs that target B4GALNT3
-
- hsa-miR-423-3p (MIRT042532)
- hsa-miR-378a-3p (MIRT043861)
- hsa-let-7a-5p (MIRT052526)
- hsa-miR-521 (MIRT641466)
- hsa-miR-5006-3p (MIRT641467)
- hsa-miR-4755-5p (MIRT641468)
- hsa-miR-211-5p (MIRT641469)
- hsa-miR-204-5p (MIRT641470)
- hsa-miR-623 (MIRT641471)
- hsa-miR-4436b-5p (MIRT641472)
- hsa-miR-6509-3p (MIRT641473)
- hsa-miR-2115-5p (MIRT641474)
- hsa-miR-6832-3p (MIRT641475)
- hsa-miR-6878-3p (MIRT719401)
- hsa-miR-6873-3p (MIRT719402)
- hsa-miR-6749-3p (MIRT719403)
- hsa-miR-6744-3p (MIRT719404)
- hsa-miR-4757-5p (MIRT719405)
- hsa-miR-6817-3p (MIRT719406)
- hsa-miR-7110-3p (MIRT719407)
- hsa-miR-4685-3p (MIRT719408)
- hsa-miR-4287 (MIRT719409)
- hsa-miR-372-5p (MIRT719410)
- hsa-miR-371a-5p (MIRT719411)
- hsa-miR-616-5p (MIRT719412)
- hsa-miR-373-5p (MIRT719413)
- hsa-miR-371b-5p (MIRT719414)
- hsa-miR-6769b-3p (MIRT719415)
- hsa-miR-4723-3p (MIRT719416)
- hsa-miR-3183 (MIRT719417)
- hsa-miR-5088-3p (MIRT719418)
- hsa-miR-520h (MIRT719419)
- hsa-miR-520g-3p (MIRT719420)
- hsa-miR-3973 (MIRT719421)
- hsa-miR-6507-3p (MIRT719422)
- hsa-miR-6881-3p (MIRT725640)
- hsa-miR-6780a-3p (MIRT725641)
- hsa-miR-7111-3p (MIRT725642)
- hsa-miR-6851-3p (MIRT725643)
- hsa-miR-6886-3p (MIRT725644)
- hsa-miR-1915-5p (MIRT725645)
- hsa-miR-3667-3p (MIRT725646)
- hsa-miR-877-3p (MIRT725647)
- hsa-miR-3910 (MIRT725648)
- hsa-miR-3714 (MIRT725649)
- hsa-miR-506-3p (MIRT725650)
- hsa-miR-124-3p (MIRT725651)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for B4GALNT3
- Browse OriGene Inhibitory RNA Products For B4GALNT3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for B4GALNT3
Clone Products
- Applied Biological Materials (abm): Clones for B4GALNT3 - Select products 50% OFF >
- * B4GALNT3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for B4GALNT3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for B4GALNT3
Cell Line Products
-
Horizon Cell Lines for B4GALNT3
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for B4GALNT3 Gene
Localization for B4GALNT3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for B4GALNT3 Gene
- Golgi apparatus, Golgi stack membrane. Single-pass type II membrane protein. Note=Localizes to apical Golgi.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| lysosome | 1 |
- Golgi apparatus (3)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0032580 | Golgi cisterna membrane | IEA | -- |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | -- |
Pathways & Interactions for B4GALNT3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism | ||
| 2 | N-Glycan biosynthesis | ||
Pathways by source for B4GALNT3 Gene
2 KEGG pathways for B4GALNT3 Gene
Interacting Proteins for B4GALNT3 Gene
GPS-Prot Interaction Network for B4GALNT3
No data available for SIGNOR curated interactions for B4GALNT3 Gene
Drugs & Compounds for B4GALNT3 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| N-Acetylgalactosamine |
|
1811-31-0 |
|
|||
| UDP-N-acetyl-alpha-D-galactosamine |
|
|
||||
| Uridine diphosphate-N-acetylgalactosamine |
|
7277-98-7 |
|
Transcripts for B4GALNT3 Gene
mRNA/cDNA for B4GALNT3 Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000266383 5493 nts (view in UCSC)
- ENST00000535680 729 nts (view in UCSC)
- ENST00000544638 553 nts (view in UCSC)
- ENST00000540836 540 nts (view in UCSC)
- ENST00000322843 1926 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for B4GALNT3 - Select products 50% OFF >
- * B4GALNT3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for B4GALNT3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for B4GALNT3
-
Santa Cruz Biotechnology (SCBT) CRISPR for B4GALNT3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for B4GALNT3
- Browse OriGene Inhibitory RNA Products For B4GALNT3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for B4GALNT3
Clone Products
- Applied Biological Materials (abm): Clones for B4GALNT3 - Select products 50% OFF >
- * B4GALNT3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for B4GALNT3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for B4GALNT3
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
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| SP1: | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||
| SP5: |
Relevant External Links for B4GALNT3 Gene
- GeneLoc Exon Structure for
- B4GALNT3
Expression for B4GALNT3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Colon (Gastrointestinal Tract)
- Pancreas (Endocrine System)
-
Stomach (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for B4GALNT3 Gene
This gene is overexpressed in Stomach (x7.6).
This gene is overexpressed in Liver (47.2) and Bone (19.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for B4GALNT3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for B4GALNT3
SOURCE GeneReport for Unigene cluster for B4GALNT3 Gene:
Hs.504416mRNA Expression by UniProt/SwissProt for B4GALNT3 Gene:
Q6L9W6-B4GN3_HUMAN
Tissue specificity:
Highly expressed in testis, colon and stomach. Weakly expressed in other tissues.
Evidence on tissue expression from TISSUES for B4GALNT3 Gene
- Stomach(2.5)
Primer Products
-
OriGene qPCR primer pairs for B4GALNT3
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for B4GALNT3 Gene
Orthologs for B4GALNT3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | B4GALNT3 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | B4GALNT3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | B4galnt3 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | B4GALNT3 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | B4galnt3 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | B4GALNT3 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | B4GALNT3 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | B4GALNT3 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | B4GALNT3 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | b4galnt3 30 |
|
||
| Str.11923 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.15475 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | b4galnt3b 30 31 |
|
OneToMany | |
| B4GALNT3 (2 of 3) 31 |
|
OneToMany | |||
| b4galnt3a 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG43313 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | mig-22 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.937 31 |
|
OneToMany |
- Species where no ortholog for B4GALNT3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for B4GALNT3 Gene
- ENSEMBL:
- Gene Tree for B4GALNT3 (if available)
- TreeFam:
- Gene Tree for B4GALNT3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for B4GALNT3: view image
Paralogs for B4GALNT3 Gene
Variants for B4GALNT3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for B4GALNT3 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 721593 | Benign: not provided | 460,460(+) | G/A | SYNONYMOUS_VARIANT | |
| 771452 | Benign: not provided | 556,741(+) | G/T | MISSENSE_VARIANT | |
| 774703 | Benign: not provided | 553,246(+) | G/C | MISSENSE_VARIANT | |
| 774704 | Benign: not provided | 553,529(+) | C/T | MISSENSE_VARIANT | |
| 781815 | Benign: not provided | 553,981(+) | G/C | SYNONYMOUS_VARIANT |
Residual Variation Intolerance Score:
87.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
14.56;
96.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for B4GALNT3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- B4GALNT3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B4GALNT3 Gene
Disorders for B4GALNT3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epithelial basement membrane dystrophy |
|
|
Search B4GALNT3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for B4GALNT3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for B4GALNT3 Gene
Publications for B4GALNT3 Gene
- Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc. (PMID: 12966086) Sato T … Narimatsu H (The Journal of biological chemistry 2003) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest. (PMID: 20360844) Arking DE … Chugh SS (PloS one 2010) 3 41
- Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa. (PMID: 16728562) Ikehara Y … Narimatsu H (Glycobiology 2006) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for B4GALNT3 Gene
- Custom Antibody ServicesOriGene Antibodies for B4GALNT3
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- Custom Assay Services
- OriGene Purified Proteins for B4GALNT3
- Search Origene for MassSpec and Protein Over-expression Lysates for B4GALNT3
- Origene Custom Protein Services for B4GALNT3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for B4GALNT3
- Browse OriGene Inhibitory RNA Products For B4GALNT3
- OriGene qPCR primer pairs for B4GALNT3
- OriGene CRISPR knockouts for B4GALNT3
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- Sino Biological Antibodies for B4GALNT3
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for B4GALNT3
- Novus Biologicals proteins for B4GALNT3
- Browse Antibodies
- Browse Peptides and Proteins
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- Abcam antibodies for B4GALNT3
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- Browse Primary Antibodies
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- Invitrogen Antibodies for B4GALNT3 (AFLGC-B4GALNT3)
- VectorBuilder Custom and pre-made DNA vectors for B4GALNT3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for B4GALNT3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for B4GALNT3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for B4GALNT3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for B4GALNT3
- Addgene plasmids for B4GALNT3
- antibodies-online: Show 10 available B4GALNT3 Antibodies ranked by validation data
- antibodies-online: Search results for available B4GALNT3 related products ranked by validation data
- antibodies-online: Search results for available B4GALNT3 related products ranked by validation data
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for B4GALNT3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for B4GALNT3
- Horizon Cell Lines for B4GALNT3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for B4GALNT3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for B4GALNT3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for B4GALNT3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for B4GALNT3
Sources for B4GALNT3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB