Aliases for B3GNT6 Gene
External Ids for B3GNT6 Gene
Previous GeneCards Identifiers for B3GNT6 Gene
The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]
GeneCards Summary for B3GNT6 Gene
B3GNT6 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 6) is a Protein Coding gene. Diseases associated with B3GNT6 include Childhood-Onset Schizophrenia and Schizophrenia. Among its related pathways are O-linked glycosylation and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include galactosyltransferase activity and beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity. An important paralog of this gene is B3GNT3.
UniProtKB/Swiss-Prot Summary for B3GNT6 Gene
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.