This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq... See more...

Aliases for B3GNT5 Gene

Aliases for B3GNT5 Gene

  • UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5 2 3 5
  • Lactosylceramide 1,3-N-Acetyl-Beta-D-Glucosaminyltransferase 2 3 4
  • UDP-GlcNAc:Beta-Gal Beta-1,3-N-Acetylglucosaminyltransferase 5 3 4
  • Beta-1,3-N-Acetylglucosaminyltransferase 5 3 4
  • Lactotriaosylceramide Synthase 3 4
  • Lc(3)Cer Synthase 3 4
  • Beta-1,3-Gn-T5 3 4
  • Lc3 Synthase 3 4
  • Beta3Gn-T5 3 4
  • BGnT-5 3 4
  • Beta 1,3 N-Acetyglucosaminyltransferase Lc3 Synthase 3
  • Beta-1,3-N-Acetylglucosaminyltransferase BGnT-5 3
  • EC 2.4.1.206 4
  • EC 2.4.1 52
  • B3GN-T5 3

External Ids for B3GNT5 Gene

Previous GeneCards Identifiers for B3GNT5 Gene

  • GC03P179760
  • GC03P183826
  • GC03P184373
  • GC03P184291
  • GC03P184453
  • GC03P182971
  • GC03P180376

Summaries for B3GNT5 Gene

Entrez Gene Summary for B3GNT5 Gene

  • This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]

GeneCards Summary for B3GNT5 Gene

B3GNT5 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5) is a Protein Coding gene. Diseases associated with B3GNT5 include Salt And Pepper Syndrome. Among its related pathways are Metabolism of proteins and Glycosphingolipid biosynthesis - lacto and neolacto series. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity. An important paralog of this gene is B3GNT6.

UniProtKB/Swiss-Prot Summary for B3GNT5 Gene

  • Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Additional gene information for B3GNT5 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for B3GNT5 Gene

Genomics for B3GNT5 Gene

GeneHancer (GH) Regulatory Elements for B3GNT5 Gene

Promoters and enhancers for B3GNT5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J183252 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 522.7 +1.7 1700 5.6 NRF1 POLR2A ZNF263 GABPA ZBTB26 HES1 MYC RUNX1 CTBP1 EZH2 B3GNT5 lnc-ATP11B-10 KLHL6 ATP11B KLHL24 RF00001-233 RNA5SP151 MCF2L2
GH03J183284 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 525.6 +33.1 33109 4.3 ZBTB40 ZNF217 ZSCAN5C TCF12 SP1 GTF2E2 JUND PHB2 FOS EP300 B3GNT5 RNA5SP151 MCCC1 KLHL6 ATP11B KLHL24 hsa-miR-5095-356 lnc-LAMP3-3 RF00001-233 lnc-ATP11B-10
GH03J183262 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 510.4 +12.6 12578 7.1 NCOR1 FOS ZIC2 TCF7 TOE1 TBX3 CTBP1 POLR2A OSR2 FOSL2 B3GNT5 RNA5SP151 RF00001-233 lnc-ATP11B-10 hsa-miR-5095-356 MCF2L2
GH03J183250 Enhancer 0.3 dbSUPER 500.7 -1.9 -1895 1.2 HDAC2 ZNF184 B3GNT5 lnc-ATP11B-10 lnc-LAMP3-1 MCF2L2
GH03J183294 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 31.9 +49.1 49052 15.8 ZNF217 JUND FOS ZNF639 ZIC2 REST TRIM28 CUX1 MYC EP300 B3GNT5 KLHL6 EIF2B5 RNA5SP151 LAMP3 MCCC1 MCF2L2 KLHL24 lnc-KLHL24-10 lnc-LAMP3-3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around B3GNT5 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for B3GNT5

Top Transcription factor binding sites by QIAGEN in the B3GNT5 gene promoter:
  • AML1a
  • Lmo2
  • Pbx1a
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • RelA
  • RORalpha1
  • Sox9

Genomic Locations for B3GNT5 Gene

Genomic Locations for B3GNT5 Gene
chr3:183,253,226-183,298,504
(GRCh38/hg38)
Size:
45,279 bases
Orientation:
Plus strand
chr3:182,971,032-183,016,292
(GRCh37/hg19)
Size:
45,261 bases
Orientation:
Plus strand

Genomic View for B3GNT5 Gene

Genes around B3GNT5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
B3GNT5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for B3GNT5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for B3GNT5 Gene

Proteins for B3GNT5 Gene

  • Protein details for B3GNT5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BYG0-B3GN5_HUMAN
    Recommended name:
    Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
    Protein Accession:
    Q9BYG0
    Secondary Accessions:
    • D3DNS5
    • Q59FE3
    • Q7L9Z5
    • Q8WWP9

    Protein attributes for B3GNT5 Gene

    Size:
    378 amino acids
    Molecular mass:
    44053 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD92754.1; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for B3GNT5 Gene

Selected DME Specific Peptides for B3GNT5 Gene

Q9BYG0:
  • ISKGFFGQIYCR
  • YPDYTAGA
  • YIDDVFMG
  • QDFWIGRVH
  • PYHPCIY
  • KSYSYRYL
  • MMTSHGH

Post-translational modifications for B3GNT5 Gene

  • Glycosylation at Asn59
  • Modification sites at PhosphoSitePlus

Domains & Families for B3GNT5 Gene

Gene Families for B3GNT5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for B3GNT5 Gene

Blocks:
  • Glycosyl transferase, family 31
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for B3GNT5 Gene

GenScript: Design optimal peptide antigens:
  • Lactotriaosylceramide synthase (B3GN5_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9BYG0

UniProtKB/Swiss-Prot:

B3GN5_HUMAN :
  • Belongs to the glycosyltransferase 31 family.
Family:
  • Belongs to the glycosyltransferase 31 family.
genes like me logo Genes that share domains with B3GNT5: view

Function for B3GNT5 Gene

Molecular function for B3GNT5 Gene

UniProtKB/Swiss-Prot Function:
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP; Xref=Rhea:RHEA:13905, ChEBI:CHEBI:15378, ChEBI:CHEBI:17103, ChEBI:CHEBI:17950, ChEBI:CHEBI:57705, ChEBI:CHEBI:58223; EC=2.4.1.206; Evidence=. ;.
UniProtKB/Swiss-Prot Induction:
Up-regulated by stimulation with retinoic acid and down-regulated with 12-O-tetradecanoylphorbol-13-acetate (TPA).

Enzyme Numbers (IUBMB) for B3GNT5 Gene

Phenotypes From GWAS Catalog for B3GNT5 Gene

Gene Ontology (GO) - Molecular Function for B3GNT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008375 acetylglucosaminyltransferase activity IBA 21873635
GO:0008376 acetylgalactosaminyltransferase activity IBA 21873635
GO:0008378 galactosyltransferase activity IEA --
GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity IDA,IBA 11384981
GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IBA 21873635
genes like me logo Genes that share ontologies with B3GNT5: view
genes like me logo Genes that share phenotypes with B3GNT5: view

Animal Models for B3GNT5 Gene

MGI Knock Outs for B3GNT5:

Animal Model Products

  • Taconic Biosciences Mouse Models for B3GNT5

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for B3GNT5 Gene

Localization for B3GNT5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for B3GNT5 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for B3GNT5 gene
Compartment Confidence
golgi apparatus 5
endoplasmic reticulum 3
extracellular 2
nucleus 2
plasma membrane 1
mitochondrion 1
peroxisome 1
cytosol 1
lysosome 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for B3GNT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005783 endoplasmic reticulum IBA 21873635
GO:0005794 Golgi apparatus IBA,IEA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with B3GNT5: view

Pathways & Interactions for B3GNT5 Gene

genes like me logo Genes that share pathways with B3GNT5: view

UniProtKB/Swiss-Prot Q9BYG0-B3GN5_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for B3GNT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation TAS,IEA 11384981
GO:0006493 protein O-linked glycosylation IBA 21873635
GO:0007275 multicellular organism development IEA --
GO:0007417 central nervous system development IDA 11384981
GO:0007420 brain development IBA 21873635
genes like me logo Genes that share ontologies with B3GNT5: view

No data available for SIGNOR curated interactions for B3GNT5 Gene

Drugs & Compounds for B3GNT5 Gene

(5) Drugs for B3GNT5 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phytosphingosine Experimental Pharma 0
Sphingosine Experimental Pharma 0
Uridine 5'-diphosphate Experimental Pharma 0
sphinganine Pharma 0
Sphingosine-1-phosphate Pharma Full agonist, Agonist endogenous second messenger and ligand for S1PR1, Endogenous agonist at S1P1-5 0

(515) Additional Compounds for B3GNT5 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
3-Dehydrosphinganine
  • 3-dehydro-D-Sphinganine
  • 3-Ketodihydrosphingosine
  • 3-Ketosphinganine
  • (2S)-2-amino-1-Hydroxyoctadecan-3-one
  • 1-Hydroxy-2-amino-3-oxo-octadecane
16105-69-4
3-O-Sulfogalactosylceramide (d18:1/12:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
852100-88-0
3-O-Sulfogalactosylceramide (d18:1/14:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
3-O-Sulfogalactosylceramide (d18:1/16:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
862509-48-6
3-O-Sulfogalactosylceramide (d18:1/18:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
244215-65-4
genes like me logo Genes that share compounds with B3GNT5: view

Transcripts for B3GNT5 Gene

mRNA/cDNA for B3GNT5 Gene

1 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for B3GNT5 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c · 5d
SP1:
SP2: -
SP3: - -
SP4: - - - - - -
SP5: - - - - -

Relevant External Links for B3GNT5 Gene

GeneLoc Exon Structure for
B3GNT5

Expression for B3GNT5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for B3GNT5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for B3GNT5 Gene

This gene is overexpressed in Esophagus - Mucosa (x5.3) and Muscle - Skeletal (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for B3GNT5 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for B3GNT5

SOURCE GeneReport for Unigene cluster for B3GNT5 Gene:

Hs.718506

mRNA Expression by UniProt/SwissProt for B3GNT5 Gene:

Q9BYG0-B3GN5_HUMAN
Tissue specificity: Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus.

Evidence on tissue expression from TISSUES for B3GNT5 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with B3GNT5: view

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for B3GNT5 Gene

Orthologs for B3GNT5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for B3GNT5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia B3GNT5 31 30
  • 99.69 (n)
OneToOne
dog
(Canis familiaris)
Mammalia B3GNT5 31 30
  • 87.23 (n)
OneToOne
cow
(Bos Taurus)
Mammalia B3GNT5 31 30
  • 86.57 (n)
OneToOne
mouse
(Mus musculus)
Mammalia B3gnt5 17 31 30
  • 84 (n)
rat
(Rattus norvegicus)
Mammalia B3gnt5 30
  • 82.36 (n)
oppossum
(Monodelphis domestica)
Mammalia B3GNT5 31
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia B3GNT5 31
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves B3GNT5 31 30
  • 75.74 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia B3GNT5 31
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia b3gnt5 30
  • 68.72 (n)
zebrafish
(Danio rerio)
Actinopterygii b3gnt5a 31 30
  • 60.98 (n)
OneToMany
b3gnt5b 31
  • 49 (a)
OneToMany
Species where no ortholog for B3GNT5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for B3GNT5 Gene

ENSEMBL:
Gene Tree for B3GNT5 (if available)
TreeFam:
Gene Tree for B3GNT5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for B3GNT5: view image

Paralogs for B3GNT5 Gene

(10) SIMAP similar genes for B3GNT5 Gene using alignment to 4 proteins:

  • B3GN5_HUMAN
  • C9IYY0_HUMAN
  • C9J368_HUMAN
  • C9J5K2_HUMAN

Pseudogenes.org Pseudogenes for B3GNT5 Gene

genes like me logo Genes that share paralogs with B3GNT5: view

Variants for B3GNT5 Gene

Additional dbSNP identifiers (rs#s) for B3GNT5 Gene

Structural Variations from Database of Genomic Variants (DGV) for B3GNT5 Gene

Variant ID Type Subtype PubMed ID
esv2726288 CNV deletion 23290073
esv2726289 CNV deletion 23290073
esv3893833 CNV gain 25118596
nsv1006872 CNV loss 25217958
nsv1145008 CNV deletion 24896259

Variation tolerance for B3GNT5 Gene

Residual Variation Intolerance Score: 47.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.42; 27.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for B3GNT5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
B3GNT5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for B3GNT5 Gene

Disorders for B3GNT5 Gene

MalaCards: The human disease database

(1) MalaCards diseases for B3GNT5 Gene - From: DISEASES

Disorder Aliases PubMed IDs
salt and pepper syndrome
  • salt & pepper syndrome
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for B3GNT5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with B3GNT5: view

No data available for UniProtKB/Swiss-Prot and Genatlas for B3GNT5 Gene

Publications for B3GNT5 Gene

  1. Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. (PMID: 11283017) Togayachi A … Narimatsu H (The Journal of biological chemistry 2001) 2 3 4 54
  2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 41 54
  3. Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis. (PMID: 11384981) Henion TR … Hennet T (The Journal of biological chemistry 2001) 3 4 54
  4. High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. (PMID: 22411838) Wang Z … Li Y (Glycobiology 2012) 3 54
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 54

Products for B3GNT5 Gene

Sources for B3GNT5 Gene