External Ids for APOD Gene
Previous GeneCards Identifiers for APOD Gene
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
GeneCards Summary for APOD Gene
APOD (Apolipoprotein D) is a Protein Coding gene. Diseases associated with APOD include Breast Cyst and Androgen Insensitivity Syndrome. Among its related pathways are Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) and Transport of vitamins, nucleosides, and related molecules. Gene Ontology (GO) annotations related to this gene include transporter activity and cholesterol binding.
UniProtKB/Swiss-Prot Summary for APOD Gene
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.