Aliases for AVPR1A Gene
External Ids for AVPR1A Gene
Previous HGNC Symbols for AVPR1A Gene
Previous GeneCards Identifiers for AVPR1A Gene
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
GeneCards Summary for AVPR1A Gene
AVPR1A (Arginine Vasopressin Receptor 1A) is a Protein Coding gene. Diseases associated with AVPR1A include Acth-Independent Macronodular Adrenal Hyperplasia and Hepatorenal Syndrome. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and protein kinase C binding. An important paralog of this gene is AVPR1B.
UniProtKB/Swiss-Prot Summary for AVPR1A Gene
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Vasopressin receptors are a group of G-protein-coupled receptors that mediate vasoconstriction, antidiuresis and ACTH release. They are currently divided into three subtypes, V1A, V1B and V2 and are closely related to oxytocin receptors (OT).