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The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. [provided by RefSeq, Jul 2008] See more...
Aliases for AVIL Gene
External Ids for AVIL Gene
- HGNC: 14188
- Entrez Gene: 10677
- Ensembl: ENSG00000135407
- OMIM: 613397
- UniProtKB: O75366
Previous GeneCards Identifiers for AVIL Gene
- GC12M058334
- GC12M057907
- GC12M056477
- GC12M058191
- GC12M055228
Summaries for AVIL Gene
-
The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. [provided by RefSeq, Jul 2008]
GeneCards Summary for AVIL Gene
AVIL (Advillin) is a Protein Coding gene. Diseases associated with AVIL include Nephrotic Syndrome, Type 21 and Nephrotic Syndrome. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is VIL1.
UniProtKB/Swiss-Prot Summary for AVIL Gene
-
Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling (PubMed:29058690). May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (PubMed:29058690).
Additional gene information for AVIL Gene
- HGNC(14188)
- Entrez Gene(10677)
- Ensembl(ENSG00000135407)
- OMIM(613397)
- UniProtKB(O75366)
- Open Targets Platform(ENSG00000135407)
- Monarch Initiative
- Search for AVIL at DataMed
- Search for AVIL at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for AVIL Gene
Genomics for AVIL Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for AVIL Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around AVIL on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for AVIL
- Top Transcription factor binding sites by QIAGEN in the AVIL gene promoter:
-
- aMEF-2
- AML1a
- E47
- Egr-3
- FOXI1
- HEN1
- HFH-3
- HOXA3
- Ik-3
- MEF-2A
Genomic Locations for AVIL Gene
Genomic Locations for AVIL Gene
- chr12:57,797,376-57,818,704
- (GRCh38/hg38)
- Size:
- 21,329 bases
- Orientation:
- Minus strand
- chr12:58,191,159-58,212,487
- (GRCh37/hg19)
- Size:
- 21,329 bases
- Orientation:
- Minus strand
Genomic View for AVIL Gene
Genes around AVIL on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q14.1 by HGNC
- 12q14.1 by Entrez Gene
- 12q14.1 by Ensembl
AVIL Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AVIL Gene
Proteins for AVIL Gene
-
Protein details for AVIL Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75366-AVIL_HUMAN
- Recommended name:
- Advillin
- Protein Accession:
- O75366
- B2RAU7
- Q2NKM9
Protein attributes for AVIL Gene
- Size:
- 819 amino acids
- Molecular mass:
- 92027 Da
- Quaternary structure:
-
- Associates (via C-terminus) with F-actin (PubMed:15096633, PubMed:29058690). Interacts with SCARF1 (By similarity). Interacts with PLCE1 (PubMed:29058690). Interacts with ACTR2 and ACTR3; associates with the ARP2/3 complex (PubMed:29058690).
Protein Expression for AVIL Gene
Post-translational modifications for AVIL Gene
Other Protein References for AVIL Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-AVIL (aa 183-212) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for AVIL
- Novus Biologicals Antibodies for AVIL
- Invitrogen Antibodies for AVIL (AFLGC-AVIL)
-
Boster Bio Antibodies for AVIL
Protein Products
-
OriGene Purified Proteins for AVIL
- Search Origene for MassSpec and Protein Over-expression Lysates for AVIL
- Origene Custom Protein Services for AVIL
- Novus Biologicals proteins for AVIL
-
Abcam proteins for AVIL
No data available for DME Specific Peptides for AVIL Gene
Domains & Families for AVIL Gene
Gene Families for AVIL Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for AVIL Gene
- InterPro:
- Blocks:
-
- Villin headpiece
- Gelsolin family signature
- Gelsolin region
- ProtoNet:
Suggested Antigen Peptide Sequences for AVIL Gene
- GenScript: Design optimal peptide antigens:
-
- p92 (AVIL_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75366- Family:
-
- Belongs to the villin/gelsolin family.
Function for AVIL Gene
Molecular function for AVIL Gene
- UniProtKB/Swiss-Prot Function:
- Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling (PubMed:29058690). May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (PubMed:29058690).
Phenotypes From GWAS Catalog for AVIL Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | ISS | -- |
| GO:0005515 | protein binding | IPI | 29058690 |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | IBA | 21873635 |
| GO:0051015 | actin filament binding | IEA,IDA | 29058690 |
| GO:0071933 | Arp2/3 complex binding | IDA | 29058690 |
Phenotypes for AVIL Gene
- MGI mutant phenotypes for AVIL:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for AVIL:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Resistant to vaccinia virus (VACV-A4L) infection
- Decreased vaccinia virus (VACV) infection
- Decreased viability ratio
- Decreased cilium length after serum starvation
- Increased shRNA abundance (Z-score > 2)
- Decreased endosome-nucleus distance (endosomes clustered in the perinuclear region)
- Increased viability
- Decreased viability after Maraba virus infection
- Decreased shRNA abundance (Z-score < -2)
- Decreased cilium length
Animal Models for AVIL Gene
- MGI Knock Outs for AVIL:
-
- Avil Avil<tm1(ALPP)Fawa>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for AVIL - Select products 50% OFF >
- * AVIL CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for AVIL
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AVIL
-
Santa Cruz Biotechnology (SCBT) CRISPR for AVIL
miRNA for AVIL Gene
- miRTarBase miRNAs that target AVIL
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for AVIL
- Browse OriGene Inhibitory RNA Products For AVIL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AVIL
Clone Products
- Applied Biological Materials (abm): Clones for AVIL - Select products 50% OFF >
- * AVIL as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for AVIL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AVIL
Cell Line Products
-
Horizon Cell Lines for AVIL
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for AVIL Gene
Localization for AVIL Gene
Subcellular locations from UniProtKB/Swiss-Prot for AVIL Gene
- Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell junction, focal adhesion. Cell projection, neuron projection. Cell projection, axon. Note=In podocytes, present in the F-actin-enriched cell periphery that generates lamellipodia and focal adhesions. {ECO:0000269 PubMed:29058690}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA,IBA | 21873635 |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005884 | actin filament | IDA | 29058690 |
| GO:0005925 | focal adhesion | IDA | 29058690 |
| GO:0015629 | actin cytoskeleton | TAS,IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for AVIL Gene
Pathways & Interactions for AVIL Gene
Interacting Proteins for AVIL Gene
GPS-Prot Interaction Network for AVIL
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007010 | cytoskeleton organization | IEA | -- |
| GO:0007015 | actin filament organization | IMP | 29058690 |
| GO:0007399 | nervous system development | TAS | 9664034 |
| GO:0008154 | actin polymerization or depolymerization | IBA | 21873635 |
| GO:0010592 | positive regulation of lamellipodium assembly | IMP | 29058690 |
No data available for Pathways by source and SIGNOR curated interactions for AVIL Gene
Transcripts for AVIL Gene
mRNA/cDNA for AVIL Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000546952 1479 nts (view in UCSC)
- ENST00000549851 2735 nts (view in UCSC)
- ENST00000551248 618 nts (view in UCSC)
- ENST00000257861 2891 nts (view in UCSC)
- ENST00000550537 1433 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for AVIL - Select products 50% OFF >
- * AVIL CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for AVIL
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AVIL
-
Santa Cruz Biotechnology (SCBT) CRISPR for AVIL
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for AVIL
- Browse OriGene Inhibitory RNA Products For AVIL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AVIL
Clone Products
- Applied Biological Materials (abm): Clones for AVIL - Select products 50% OFF >
- * AVIL as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for AVIL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AVIL
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - |
| ExUns: | 20a | · | 20b | · | 20c |
|---|---|---|---|---|---|
| SP1: | |||||
| SP2: | |||||
| SP3: | |||||
| SP4: | |||||
| SP5: |
Relevant External Links for AVIL Gene
- GeneLoc Exon Structure for
- AVIL
Expression for AVIL Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Neural Tube (Nervous System)
This gene is overexpressed in Spinal cord (57.3) and Liver, secretome (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AVIL Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for AVIL
SOURCE GeneReport for Unigene cluster for AVIL Gene:
Hs.584854mRNA Expression by UniProt/SwissProt for AVIL Gene:
O75366-AVIL_HUMAN
Tissue specificity:
Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus (PubMed:12034507). Expressed in podocytes (at protein level) (PubMed:29058690).
Evidence on tissue expression from TISSUES for AVIL Gene
- Nervous system(4.5)
- Skin(2.3)
- Blood(2)
Primer Products
-
OriGene qPCR primer pairs for AVIL
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for AVIL Gene
Orthologs for AVIL Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | AVIL 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | AVIL 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | AVIL 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Avil 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Avil 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | AVIL 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | AVIL 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | avil 30 |
|
||
| Str.5242 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | avil 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | Gel 32 |
|
|
|
| Worm (Caenorhabditis elegans) |
Secernentea | K06A4.3 32 |
|
|
|
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | VLN2 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os03g0356700 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for AVIL was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for AVIL Gene
- ENSEMBL:
- Gene Tree for AVIL (if available)
- TreeFam:
- Gene Tree for AVIL (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for AVIL: view image
Paralogs for AVIL Gene
Variants for AVIL Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for AVIL Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 684648 | Pathogenic: Steroid-resistant nephrotic syndrome; NEPHROTIC SYNDROME, TYPE 21 | 57,807,649(-) | G/T | MISSENSE_VARIANT | |
| 684649 | Pathogenic: Steroid-resistant nephrotic syndrome; NEPHROTIC SYNDROME, TYPE 21 | 57,807,485(-) | C/T | MISSENSE_VARIANT | |
| 684650 | Pathogenic: Steroid-resistant nephrotic syndrome; NEPHROTIC SYNDROME, TYPE 21 | 57,811,062(-) | C/T | MISSENSE_VARIANT | |
| 684651 | Pathogenic: Steroid-resistant nephrotic syndrome; NEPHROTIC SYNDROME, TYPE 21 | 57,802,346(-) | C/CA | FRAMESHIFT_VARIANT,INTRON_VARIANT | |
| 713418 | Benign: not provided | 57,816,005(-) | G/A | SYNONYMOUS_VARIANT |
Residual Variation Intolerance Score:
86.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.97;
49.56% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for AVIL Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AVIL
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AVIL Gene
Disorders for AVIL Gene
(5) MalaCards diseases for AVIL Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| nephrotic syndrome, type 21 |
|
|
| nephrotic syndrome |
|
|
| combined oxidative phosphorylation deficiency 3 |
|
|
| uvulitis |
|
|
| migraine with or without aura 1 |
|
|
Search AVIL in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
AVIL_HUMAN- Nephrotic syndrome 21 (NPHS21) [MIM:618594]: A form of nephrotic syndrome, a renal disease clinically characterized by severe proteinuria, resulting in complications such as hypoalbuminemia, hyperlipidemia and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. Some affected individuals have an inherited steroid-resistant form that progresses to end-stage renal failure. NPHS21 is an autosomal recessive, rapidly progressive, steroid-resistant form characterized by onset of kidney dysfunction in the first year of life. Some patients may have variable extra-renal manifestations. {ECO:0000269 PubMed:29058690}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for AVIL
No data available for Genatlas for AVIL Gene
Publications for AVIL Gene
- Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins. (PMID: 9664034) Marks PW … Kwiatkowski DJ (Journal of cell science 1998) 2 3 4 23
- Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirements. (PMID: 15096633) Vermeulen W … Borremans FA (Protein science : a publication of the Protein Society 2004) 3 4 23
- Genomic structure, chromosome mapping and expression analysis of the human AVIL gene, and its exclusion as a candidate for locus for inflammatory bowel disease at 12q13-14 (IBD2). (PMID: 12034507) Tümer Z … Schreiber S (Gene 2002) 2 3 4
- Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome. (PMID: 29058690) Rao J … Hildebrandt F (The Journal of clinical investigation 2017) 3 4
- Functional genomic screen for modulators of ciliogenesis and cilium length. (PMID: 20393563) Kim J … Gleeson JG (Nature 2010) 3 4
ExternalLinks
Products for AVIL Gene
- Custom Antibody ServicesOriGene Antibodies for AVIL
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for AVIL
- Search Origene for MassSpec and Protein Over-expression Lysates for AVIL
- Origene Custom Protein Services for AVIL
- Origene shrna, sirna, and RNAi products in human, mouse, rat for AVIL
- Browse OriGene Inhibitory RNA Products For AVIL
- OriGene qPCR primer pairs for AVIL
- OriGene CRISPR knockouts for AVIL
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For AVIL
- Sino Biological Human cDNA Clone for AVIL
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for AVIL
- Novus Biologicals proteins for AVIL
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for AVIL
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for AVIL (AFLGC-AVIL)
- VectorBuilder Custom and pre-made DNA vectors for AVIL (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for AVIL (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for AVIL (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for AVIL CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for AVIL
- antibodies-online: Show 15 available AVIL Antibodies ranked by validation data
- Compare Top AVIL Antibodies
- antibodies-online: Search results for available AVIL related products ranked by validation data
- antibodies-online: Show 4 available AVIL Proteins ranked by validation data
- Compare Top AVIL Proteins
- Horizon Cell Lines for AVIL
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AVIL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AVIL
- Search GeneCopoeia for miRNA 3'UTR Target clone products for AVIL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AVIL
- Boster Bio Antibodies for AVIL
- Browse Boster Bio ELISA Kits
Sources for AVIL Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
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