Aliases for ATXN1L Gene
External Ids for ATXN1L Gene
Previous GeneCards Identifiers for ATXN1L Gene
GeneCards Summary for ATXN1L Gene
ATXN1L (Ataxin 1 Like) is a Protein Coding gene. Diseases associated with ATXN1L include Spinocerebellar Ataxia 1. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is ATXN1.
UniProtKB/Swiss-Prot for ATXN1L Gene
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity).