Aliases for ATRN Gene
External Ids for ATRN Gene
Previous GeneCards Identifiers for ATRN Gene
This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]
GeneCards Summary for ATRN Gene
ATRN (Attractin) is a Protein Coding gene. Diseases associated with ATRN include Shwartzman Phenomenon and 3-Methylglutaconic Aciduria, Type Iv. Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is ATRNL1.
UniProtKB/Swiss-Prot for ATRN Gene
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).