Aliases for ATRN Gene
External Ids for ATRN Gene
Previous GeneCards Identifiers for ATRN Gene
This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]
GeneCards Summary for ATRN Gene
ATRN (Attractin) is a Protein Coding gene. Diseases associated with ATRN include Shwartzman Phenomenon and Hypomyelinating Leukodystrophy. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is ATRNL1.
UniProtKB/Swiss-Prot for ATRN Gene
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).