Aliases for ATP6V0D2 Gene
External Ids for ATP6V0D2 Gene
Previous HGNC Symbols for ATP6V0D2 Gene
Previous GeneCards Identifiers for ATP6V0D2 Gene
GeneCards Summary for ATP6V0D2 Gene
ATP6V0D2 (ATPase H+ Transporting V0 Subunit D2) is a Protein Coding gene. Diseases associated with ATP6V0D2 include Autosomal Recessive Distal Renal Tubular Acidosis and Distal Renal Tubular Acidosis. Among its related pathways are Insulin receptor recycling and Lysosome. Gene Ontology (GO) annotations related to this gene include proton transmembrane transporter activity. An important paralog of this gene is ATP6V0D1.
UniProtKB/Swiss-Prot Summary for ATP6V0D2 Gene
Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity).
H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane organelles such as vacuoles, lysosomes and endosomes.