This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed... See more...

Aliases for ATP6V0D1 Gene

Aliases for ATP6V0D1 Gene

  • ATPase H+ Transporting V0 Subunit D1 2 3 5
  • ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 2 2 3
  • ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Member D 2 3
  • V-ATPase 40 KDa Accessory Protein 3 4
  • V-Type Proton ATPase Subunit D 1 3 4
  • Vacuolar Proton Pump Subunit D 1 3 4
  • 32 KDa Accessory Protein 3 4
  • V-ATPase AC39 Subunit 3 4
  • V-ATPase Subunit D 1 3 4
  • VPATPD 3 4
  • ATP6D 3 4
  • P39 3 4
  • ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D Isoform 1 2
  • H(+)-Transporting Two-Sector ATPase, Subunit D 3
  • V-ATPase, Subunit D 3
  • ATP6DV 3
  • VATX 3
  • VMA6 3

External Ids for ATP6V0D1 Gene

Previous HGNC Symbols for ATP6V0D1 Gene

  • ATP6D

Previous GeneCards Identifiers for ATP6V0D1 Gene

  • GC16M058166
  • GC16M067849
  • GC16M067207
  • GC16M067248
  • GC16M066029
  • GC16M067471
  • GC16M053345

Summaries for ATP6V0D1 Gene

Entrez Gene Summary for ATP6V0D1 Gene

  • This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

GeneCards Summary for ATP6V0D1 Gene

ATP6V0D1 (ATPase H+ Transporting V0 Subunit D1) is a Protein Coding gene. Diseases associated with ATP6V0D1 include Tinea Nigra. Among its related pathways are Insulin receptor recycling and Synaptic vesicle cycle. Gene Ontology (GO) annotations related to this gene include proton-exporting ATPase activity, phosphorylative mechanism. An important paralog of this gene is ATP6V0D2.

UniProtKB/Swiss-Prot Summary for ATP6V0D1 Gene

  • Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Tocris Summary for ATP6V0D1 Gene

  • H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane organelles such as vacuoles, lysosomes and endosomes.

Gene Wiki entry for ATP6V0D1 Gene

Additional gene information for ATP6V0D1 Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ATP6V0D1 Gene

Genomics for ATP6V0D1 Gene

GeneHancer (GH) Regulatory Elements for ATP6V0D1 Gene

Promoters and enhancers for ATP6V0D1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ATP6V0D1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ATP6V0D1

Top Transcription factor binding sites by QIAGEN in the ATP6V0D1 gene promoter:
  • CREB
  • deltaCREB

Genomic Locations for ATP6V0D1 Gene

Genomic Locations for ATP6V0D1 Gene
chr16:67,438,014-67,481,186
(GRCh38/hg38)
Size:
43,173 bases
Orientation:
Minus strand
chr16:67,471,917-67,515,140
(GRCh37/hg19)
Size:
43,224 bases
Orientation:
Minus strand

Genomic View for ATP6V0D1 Gene

Genes around ATP6V0D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ATP6V0D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ATP6V0D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ATP6V0D1 Gene

Proteins for ATP6V0D1 Gene

  • Protein details for ATP6V0D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P61421-VA0D1_HUMAN
    Recommended name:
    V-type proton ATPase subunit d 1
    Protein Accession:
    P61421
    Secondary Accessions:
    • P12953
    • Q02547

    Protein attributes for ATP6V0D1 Gene

    Size:
    351 amino acids
    Molecular mass:
    40329 Da
    Quaternary structure:
    • V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d) (By similarity). Interacts with PIP4P1 (PubMed:29644770).
    SequenceCaution:
    • Sequence=CAA50591.1; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for ATP6V0D1 Gene

Post-translational modifications for ATP6V0D1 Gene

  • Ubiquitination at Lys265, Lys275, Lys288, and Lys343
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ATP6V0D1 Gene

Domains & Families for ATP6V0D1 Gene

Gene Families for ATP6V0D1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transporters

Protein Domains for ATP6V0D1 Gene

Suggested Antigen Peptide Sequences for ATP6V0D1 Gene

GenScript: Design optimal peptide antigens:
  • ATPase H+ transporting V0 subunit D1 (C6SUN6_HUMAN)
  • Vacuolar proton pump subunit d 1 (VA0D1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P61421

UniProtKB/Swiss-Prot:

VA0D1_HUMAN :
  • Belongs to the V-ATPase V0D/AC39 subunit family.
Family:
  • Belongs to the V-ATPase V0D/AC39 subunit family.
genes like me logo Genes that share domains with ATP6V0D1: view

Function for ATP6V0D1 Gene

Molecular function for ATP6V0D1 Gene

UniProtKB/Swiss-Prot Function:
Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Phenotypes From GWAS Catalog for ATP6V0D1 Gene

Gene Ontology (GO) - Molecular Function for ATP6V0D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 18752060
GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism IEA,IBA 21873635
GO:0015078 proton transmembrane transporter activity IEA --
GO:0044877 protein-containing complex binding IEA --
GO:0046961 proton-transporting ATPase activity, rotational mechanism IBA 21873635
genes like me logo Genes that share ontologies with ATP6V0D1: view
genes like me logo Genes that share phenotypes with ATP6V0D1: view

Animal Models for ATP6V0D1 Gene

MGI Knock Outs for ATP6V0D1:

Animal Model Products

  • Taconic Biosciences Mouse Models for ATP6V0D1

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ATP6V0D1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ATP6V0D1 Gene

Localization for ATP6V0D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ATP6V0D1 Gene

Membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to centrosome and the base of the cilium.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ATP6V0D1 gene
Compartment Confidence
endosome 4
plasma membrane 3
cytosol 3
cytoskeleton 2
nucleus 2
lysosome 2
extracellular 1
mitochondrion 1
endoplasmic reticulum 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ATP6V0D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005623 cell IEA --
GO:0005765 lysosomal membrane IBA 21873635
GO:0005769 early endosome IBA,IEA 21873635
GO:0005813 colocalizes_with centrosome IDA 21844891
GO:0008021 synaptic vesicle IEA --
genes like me logo Genes that share ontologies with ATP6V0D1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ATP6V0D1 Gene

Pathways & Interactions for ATP6V0D1 Gene

genes like me logo Genes that share pathways with ATP6V0D1: view

Gene Ontology (GO) - Biological Process for ATP6V0D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0006879 cellular iron ion homeostasis IMP 28296633
GO:0007034 vacuolar transport IBA 21873635
GO:0007035 vacuolar acidification IBA 21873635
GO:0007420 brain development IEA --
genes like me logo Genes that share ontologies with ATP6V0D1: view

No data available for SIGNOR curated interactions for ATP6V0D1 Gene

Drugs & Compounds for ATP6V0D1 Gene

(15) Drugs for ATP6V0D1 Gene - From: ApexBio, HMDB, and Tocris

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Digoxin Approved Pharma Na+/K+ ATPase inhibitor 170
Water Approved Pharma 0
Brefeldin A Experimental Pharma Disrupts protein translocation to Golgi 0
Bafilomycin A1 Experimental Pharma V-ATPase inhibitor,selective and reversible, H+-ATPase (vacuolar) inhibitor 0
Concanamycin A Experimental Pharma V-type (vacuolar) H+-ATPase inhibitor, H+-ATPase (vacuolar) inhibitor 0

(2) Additional Compounds for ATP6V0D1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Full agonist, Agonist, Partial agonist, Antagonist, Gating inhibitor 58-64-0
Phosphate
  • [po(OH)3]
  • Acide phosphorique
  • Acidum phosphoricum
  • H3PO4
  • Orthophosphoric acid
14066-19-4, 14265-44-2

(2) Tocris Compounds for ATP6V0D1 Gene

Compound Action Cas Number
Bafilomycin A1 H+-ATPase (vacuolar) inhibitor 88899-55-2
Concanamycin A H+-ATPase (vacuolar) inhibitor 80890-47-7

(11) ApexBio Compounds for ATP6V0D1 Gene

Compound Action Cas Number
(-)-Blebbistatin Non muscle myosin II ATPase inhibitor 856925-71-8
BHQ 88-58-4
Brefeldin A 20350-15-6
BTB06584 F1F0 ATP synthases 219793-45-0
Ciclopirox ethanolamine 41621-49-2
Digoxin 20830-75-5
Golgicide A 1139889-93-2
Oligomycin A Mitochondrial ATP synthase Inhibitor 579-13-5
PF-03716556 Acid pump antagonist,potent and selective 928774-43-0
Sodium Orthovanadate PTP inhibitor 13721-39-6
TAK-438 Blocker of potassium-competitive acid 1260141-27-2
genes like me logo Genes that share compounds with ATP6V0D1: view

Drug Products

Transcripts for ATP6V0D1 Gene

mRNA/cDNA for ATP6V0D1 Gene

1 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ATP6V0D1

Alternative Splicing Database (ASD) splice patterns (SP) for ATP6V0D1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11
SP1: - - - - - -
SP2: - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: -
SP6: - - - -
SP7:
SP8: - -

Relevant External Links for ATP6V0D1 Gene

GeneLoc Exon Structure for
ATP6V0D1

Expression for ATP6V0D1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ATP6V0D1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ATP6V0D1 Gene

This gene is overexpressed in Whole Blood (x6.7).

Protein differential expression in normal tissues from HIPED for ATP6V0D1 Gene

This gene is overexpressed in Bone (21.1), Brain (12.8), and Frontal cortex (9.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ATP6V0D1 Gene



Protein tissue co-expression partners for ATP6V0D1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ATP6V0D1

SOURCE GeneReport for Unigene cluster for ATP6V0D1 Gene:

Hs.106876

mRNA Expression by UniProt/SwissProt for ATP6V0D1 Gene:

P61421-VA0D1_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for ATP6V0D1 Gene

  • Nervous system(4.9)
  • Lung(2.9)
  • Intestine(2.5)
  • Kidney(2.5)
  • Blood(2)
genes like me logo Genes that share expression patterns with ATP6V0D1: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ATP6V0D1 Gene

Orthologs for ATP6V0D1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ATP6V0D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ATP6V0D1 31 30
  • 98.01 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 97 (a)
OneToMany
-- 31
  • 75 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ATP6V0D1 31 30
  • 92.59 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ATP6V0D1 31 30
  • 91.74 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Atp6v0d1 30
  • 90.5 (n)
mouse
(Mus musculus)
Mammalia Atp6v0d1 17 31 30
  • 90.12 (n)
chicken
(Gallus gallus)
Aves -- 31
  • 98 (a)
OneToMany
-- 31
  • 95 (a)
OneToMany
-- 31
  • 91 (a)
OneToMany
ATP6V0D1 30
  • 84.05 (n)
lizard
(Anolis carolinensis)
Reptilia ATP6V0D1 31
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia atp6v0d1 30
  • 76.64 (n)
MGC76083 30
African clawed frog
(Xenopus laevis)
Amphibia atp6d-prov 30
zebrafish
(Danio rerio)
Actinopterygii atp6v0d1 31 30
  • 78.07 (n)
OneToOne
wufb73h07 30
fruit fly
(Drosophila melanogaster)
Insecta VhaAC39 32
  • 81 (a)
VhaAC39-1 31 30
  • 76.68 (n)
ManyToMany
VhaAC39-2 31
  • 44 (a)
ManyToMany
CG4624 32
  • 44 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000721 30
  • 76.44 (n)
worm
(Caenorhabditis elegans)
Secernentea C30F8.2 32
  • 75 (a)
vha-16 31 30
  • 67.83 (n)
OneToMany
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER146C 30
  • 57.5 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes VMA6 33 31 30
  • 52.96 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B04752g 30
  • 52.07 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G28710 30
  • 55.72 (n)
rice
(Oryza sativa)
Liliopsida Os01g0587000 30
  • 57.82 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9989 31
  • 71 (a)
OneToMany
Cin.4049 30
bread mold
(Neurospora crassa)
Ascomycetes NCU03395 30
  • 62.02 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes vma6 30
  • 52.94 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4049 30
Species where no ortholog for ATP6V0D1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ATP6V0D1 Gene

ENSEMBL:
Gene Tree for ATP6V0D1 (if available)
TreeFam:
Gene Tree for ATP6V0D1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ATP6V0D1: view image

Paralogs for ATP6V0D1 Gene

Paralogs for ATP6V0D1 Gene

(1) SIMAP similar genes for ATP6V0D1 Gene using alignment to 13 proteins:

  • VA0D1_HUMAN
  • C6SUN6_HUMAN
  • F5GYQ1_HUMAN
  • F8WEN9_HUMAN
  • H3BPS0_HUMAN
  • H3BQB4_HUMAN
  • H3BQJ1_HUMAN
  • H3BSG7_HUMAN
  • H3BTB4_HUMAN
  • H3BTB5_HUMAN
  • H3BUQ0_HUMAN
  • J3QL14_HUMAN
  • R4GN72_HUMAN
genes like me logo Genes that share paralogs with ATP6V0D1: view

Variants for ATP6V0D1 Gene

Additional dbSNP identifiers (rs#s) for ATP6V0D1 Gene

Structural Variations from Database of Genomic Variants (DGV) for ATP6V0D1 Gene

Variant ID Type Subtype PubMed ID
esv2247849 CNV deletion 18987734
esv2622215 CNV deletion 19546169
esv2678491 CNV deletion 23128226
esv2714648 CNV deletion 23290073
esv3553599 CNV deletion 23714750
nsv1070769 CNV deletion 25765185
nsv471092 CNV gain 18288195
nsv522852 CNV gain 19592680
nsv524363 CNV loss 19592680
nsv833266 CNV loss 17160897
nsv952045 CNV deletion 24416366

Variation tolerance for ATP6V0D1 Gene

Residual Variation Intolerance Score: 24.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.32; 7.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ATP6V0D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ATP6V0D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ATP6V0D1 Gene

Disorders for ATP6V0D1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ATP6V0D1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
tinea nigra
  • infection by cladosporium werneckii
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ATP6V0D1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ATP6V0D1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ATP6V0D1 Gene

Publications for ATP6V0D1 Gene

  1. Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase. (PMID: 8250920) van Hille B … Bilbe G (Biochemical and biophysical research communications 1993) 2 3 4 54
  2. TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation. (PMID: 29644770) Hashimoto Y … Nakayama KI (Genes to cells : devoted to molecular & cellular mechanisms 2018) 3 4 54
  3. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels. (PMID: 28296633) Miles AL … Nathan JA (eLife 2017) 3 4 54
  4. A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo. (PMID: 21844891) Chen Y … Pei D (Cell research 2012) 3 4 54
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41 54

Products for ATP6V0D1 Gene

Sources for ATP6V0D1 Gene