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Aliases for ATP5MF-PTCD1 Gene

Aliases for ATP5MF-PTCD1 Gene

  • ATP5MF-PTCD1 Readthrough 2 3
  • ATP5J2-PTCD1 Readthrough 2 3 5
  • ATP5J2-PTCD1 3 5
  • ATP5J2-PTCD1 Read-Through Transcript 3
  • ATP5J2-PTCD1 Fusion Protein 3

External Ids for ATP5MF-PTCD1 Gene

Previous HGNC Symbols for ATP5MF-PTCD1 Gene

  • ATP5J2-PTCD1

Summaries for ATP5MF-PTCD1 Gene

Entrez Gene Summary for ATP5MF-PTCD1 Gene

  • This locus represents naturally occurring read-through transcription between the ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and PTCD1 (pentatricopeptide repeat domain 1) genes on chromosome 7. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]

GeneCards Summary for ATP5MF-PTCD1 Gene

ATP5MF-PTCD1 (ATP5MF-PTCD1 Readthrough) is a Protein Coding gene. An important paralog of this gene is PTCD1.

Additional gene information for ATP5MF-PTCD1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ATP5MF-PTCD1 Gene

Genomics for ATP5MF-PTCD1 Gene

GeneHancer (GH) Regulatory Elements for ATP5MF-PTCD1 Gene

Promoters and enhancers for ATP5MF-PTCD1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I099464 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +0.4 396 2 MLX DMAP1 YY1 SLC30A9 ZNF213 ZNF143 SP3 NFYC MEF2D GLIS1 PTCD1 ATP5MF ATP5MF-PTCD1 ZSCAN25 ZNF3 ZNF655 TRIM4 TRRAP LOC101927550 LOC100131859
GH07I099557 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 11.2 -94.8 -94785 7.9 ZFP64 DMAP1 YY1 E2F8 ZNF143 SP3 MEF2D SSRP1 GLIS1 NBN ZNF655 FAM200A ZSCAN25 ZNF3 TRIM4 PTCD1 LOC101927550 ZNF394 LOC100419643 TRRAP
GH07I099437 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +26.8 26828 3.3 HDGF PKNOX1 CLOCK SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZBTB7B PTCD1 CPSF4 PIR43796 ZSCAN21 LOC100131859 AP4M1 TAF6 ZSCAN25 TRRAP CNPY4
GH07I099459 Enhancer 0.6 ENCODE 0.4 +6.9 6918 0.1 CTCF SMAD5 NFATC3 MZF1 ZNF501 RAD21 PRDM2 CBX1 POLR2A ZNF143 ZNF394 ZKSCAN5 PDAP1 BUD31 PTCD1 ATP5MF-PTCD1 ATP5MF LOC100131859
GH07I099457 Enhancer 0.5 ENCODE 0.4 +8.3 8298 0 PAF1 POLR2B POLR2A ZBED1 SUPT5H ZKSCAN5 ZNF394 BUD31 PDAP1 ATP5MF ATP5MF-PTCD1 PTCD1 LOC100131859
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ATP5MF-PTCD1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ATP5MF-PTCD1 Gene

Genomic Locations for ATP5MF-PTCD1 Gene
chr7:99,416,739-99,466,201
(GRCh38/hg38)
Size:
49,463 bases
Orientation:
Minus strand
chr7:99,014,362-99,063,824
(GRCh37/hg19)

Genomic View for ATP5MF-PTCD1 Gene

Genes around ATP5MF-PTCD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ATP5MF-PTCD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ATP5MF-PTCD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ATP5MF-PTCD1 Gene

Proteins for ATP5MF-PTCD1 Gene

  • Protein details for ATP5MF-PTCD1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    C9JJT5
    Recommended name:
    ATP5J2-PTCD1 readthrough
    Protein Accession:
    C9JJT5

    Protein attributes for ATP5MF-PTCD1 Gene

    Size:
    54 amino acids
    Molecular mass:
    5915 Da
    Quaternary structure:
    No Data Available
  • Protein details for ATP5MF-PTCD1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    G3V325
    Recommended name:
    ATP5J2-PTCD1 readthrough
    Protein Accession:
    G3V325

    Protein attributes for ATP5MF-PTCD1 Gene

    Size:
    749 amino acids
    Molecular mass:
    84110 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ATP5MF-PTCD1 Gene

Post-translational modifications for ATP5MF-PTCD1 Gene

No Post-translational modifications

Other Protein References for ATP5MF-PTCD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ATP5MF-PTCD1 Gene

Domains & Families for ATP5MF-PTCD1 Gene

Gene Families for ATP5MF-PTCD1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ATP5MF-PTCD1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ATP5MF-PTCD1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ATP5MF-PTCD1 Gene

Function for ATP5MF-PTCD1 Gene

Phenotypes for ATP5MF-PTCD1 Gene

genes like me logo Genes that share phenotypes with ATP5MF-PTCD1: view

Animal Model Products

CRISPR Products

miRNA for ATP5MF-PTCD1 Gene

miRTarBase miRNAs that target ATP5MF-PTCD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ATP5MF-PTCD1 Gene

Localization for ATP5MF-PTCD1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ATP5MF-PTCD1 gene
Compartment Confidence
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ATP5MF-PTCD1 Gene

Pathways & Interactions for ATP5MF-PTCD1 Gene

SuperPathways for ATP5MF-PTCD1 Gene

No Data Available

Interacting Proteins for ATP5MF-PTCD1 Gene

Gene Ontology (GO) - Biological Process for ATP5MF-PTCD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ATP5MF-PTCD1 Gene

Drugs & Compounds for ATP5MF-PTCD1 Gene

No Compound Related Data Available

Transcripts for ATP5MF-PTCD1 Gene

mRNA/cDNA for ATP5MF-PTCD1 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ATP5MF-PTCD1 Gene

No ASD Table

Relevant External Links for ATP5MF-PTCD1 Gene

GeneLoc Exon Structure for
ATP5MF-PTCD1
ECgene alternative splicing isoforms for
ATP5MF-PTCD1

Expression for ATP5MF-PTCD1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ATP5MF-PTCD1 Gene

Orthologs for ATP5MF-PTCD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ATP5MF-PTCD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ATP5J2 33
  • 99.24 (n)
-- 34
  • 99 (a)
OneToMany
dog
(Canis familiaris)
Mammalia PTCD1 33
  • 81.16 (n)
-- 34
  • 76 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Ptcd1 34 16 33
  • 79.52 (n)
OneToMany
rat
(Rattus norvegicus)
Mammalia Ptcd1 33
  • 78.47 (n)
cow
(Bos Taurus)
Mammalia -- 34
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 57 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 46 (a)
OneToMany
chicken
(Gallus gallus)
Aves PTCD1 33
  • 63.01 (n)
-- 34
  • 55 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 53 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia ptcd1 33
  • 57.17 (n)
zebrafish
(Danio rerio)
Actinopterygii ptcd1 34 33
  • 55.15 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006051 33
  • 50.93 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG4611 33 34
  • 48.84 (n)
Species where no ortholog for ATP5MF-PTCD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ATP5MF-PTCD1 Gene

ENSEMBL:
Gene Tree for ATP5MF-PTCD1 (if available)
TreeFam:
Gene Tree for ATP5MF-PTCD1 (if available)

Paralogs for ATP5MF-PTCD1 Gene

Paralogs for ATP5MF-PTCD1 Gene

genes like me logo Genes that share paralogs with ATP5MF-PTCD1: view

Variants for ATP5MF-PTCD1 Gene

Sequence variations from dbSNP and Humsavar for ATP5MF-PTCD1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs201365604 uncertain-significance, not specified 99,434,948(-) G/A coding_sequence_variant, missense_variant
rs886043246 uncertain-significance, not specified 99,420,092(-) G/A coding_sequence_variant, stop_gained
rs150504114 benign, not specified 99,434,936(-) G/A coding_sequence_variant, missense_variant
rs1000026358 -- 99,416,421(-) T/G downstream_transcript_variant
rs1000093689 -- 99,467,355(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ATP5MF-PTCD1 Gene

Variant ID Type Subtype PubMed ID
esv2734882 CNV deletion 23290073
esv3542149 CNV deletion 23714750
nsv5864 CNV insertion 18451855
nsv831069 CNV loss 17160897
nsv951382 CNV deletion 24416366
nsv951383 CNV deletion 24416366

Variation tolerance for ATP5MF-PTCD1 Gene

Residual Variation Intolerance Score: 87.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.35; 63.30% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ATP5MF-PTCD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ATP5MF-PTCD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ATP5MF-PTCD1 Gene

Disorders for ATP5MF-PTCD1 Gene

Additional Disease Information for ATP5MF-PTCD1

No disorders were found for ATP5MF-PTCD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ATP5MF-PTCD1 Gene

Publications for ATP5MF-PTCD1 Gene

  1. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q … Chinnaiyan AM (Nature communications 2014) 3 58
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 3 58
  5. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 58

Products for ATP5MF-PTCD1 Gene

Sources for ATP5MF-PTCD1 Gene

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