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Aliases for ATP5F1EP2 Gene

Aliases for ATP5F1EP2 Gene

  • ATP Synthase F1 Subunit Epsilon Pseudogene 2 2 3 5
  • ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Epsilon Subunit Pseudogene 2 2 3
  • ATP5EP2 3

External Ids for ATP5F1EP2 Gene

Previous HGNC Symbols for ATP5F1EP2 Gene

  • ATP5EP2

Summaries for ATP5F1EP2 Gene

GeneCards Summary for ATP5F1EP2 Gene

ATP5F1EP2 (ATP Synthase F1 Subunit Epsilon Pseudogene 2) is a Pseudogene. Among its related pathways are purine nucleotides de novo biosynthesis.

Additional gene information for ATP5F1EP2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ATP5F1EP2 Gene

Genomics for ATP5F1EP2 Gene

GeneHancer (GH) Regulatory Elements for ATP5F1EP2 Gene

Promoters and enhancers for ATP5F1EP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J027919 Promoter/Enhancer 1.4 EPDnew ENCODE dbSUPER 0.3 -23.6 -23574 3.5 USF1 ZBTB6 SUZ12 MAX EBF1 ZNF335 GLIS2 POLR2A PATZ1 NFYB PDX1 PLUT ATP5F1EP2
GH13J027928 Enhancer 0.6 ENCODE dbSUPER 0.4 -17.0 -16987 0 SUZ12 EZH2 CDX2 GSX1 PLUT ATP5F1EP2
GH13J027924 Enhancer 0.6 ENCODE dbSUPER 0.3 -20.9 -20907 0.2 SUZ12 EZH2 CDX2 GSX1 PLUT PDX1 ATP5F1EP2
GH13J027927 Enhancer 0.4 dbSUPER 0.4 -17.9 -17912 0.3 SUZ12 CTBP2 EZH2 CDX2 GSX1 PLUT ATP5F1EP2
GH13J027929 Enhancer 0.4 dbSUPER 0.4 -16.0 -16021 0.4 SUZ12 EZH2 CDX2 GSX1 PLUT ATP5F1EP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ATP5F1EP2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ATP5F1EP2 Gene

Genomic Locations for ATP5F1EP2 Gene
chr13:27,945,206-27,945,573
(GRCh38/hg38)
Size:
368 bases
Orientation:
Plus strand
chr13:28,519,343-28,519,727
(GRCh37/hg19)

Genomic View for ATP5F1EP2 Gene

Genes around ATP5F1EP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ATP5F1EP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ATP5F1EP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ATP5F1EP2 Gene

Proteins for ATP5F1EP2 Gene

Post-translational modifications for ATP5F1EP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ATP5F1EP2 Gene

Domains & Families for ATP5F1EP2 Gene

Gene Families for ATP5F1EP2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for ATP5F1EP2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ATP5F1EP2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for ATP5F1EP2 Gene

Function for ATP5F1EP2 Gene

Gene Ontology (GO) - Molecular Function for ATP5F1EP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016887 contributes_to ATPase activity IBA --
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism IEA --
genes like me logo Genes that share ontologies with ATP5F1EP2: view
genes like me logo Genes that share phenotypes with ATP5F1EP2: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ATP5F1EP2 Gene

Localization for ATP5F1EP2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ATP5F1EP2 gene
Compartment Confidence
mitochondrion 5
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for ATP5F1EP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) IEA --
GO:0005739 mitochondrion HDA 20833797
GO:0005743 mitochondrial inner membrane IBA --
genes like me logo Genes that share ontologies with ATP5F1EP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for ATP5F1EP2 Gene

Pathways & Interactions for ATP5F1EP2 Gene

genes like me logo Genes that share pathways with ATP5F1EP2: view

Interacting Proteins for ATP5F1EP2 Gene

Gene Ontology (GO) - Biological Process for ATP5F1EP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015986 ATP synthesis coupled proton transport IEA --
GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA --
genes like me logo Genes that share ontologies with ATP5F1EP2: view

No data available for SIGNOR curated interactions for ATP5F1EP2 Gene

Drugs & Compounds for ATP5F1EP2 Gene

(1) Drugs for ATP5F1EP2 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Clotrimazole Approved, Vet_approved Pharma Inhibition, Pore Blocker, Antagonist, Agonist, Channel blocker, Gating inhibitor 38
genes like me logo Genes that share compounds with ATP5F1EP2: view

Transcripts for ATP5F1EP2 Gene

mRNA/cDNA for ATP5F1EP2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ATP5F1EP2 Gene

No ASD Table

Relevant External Links for ATP5F1EP2 Gene

GeneLoc Exon Structure for
ATP5F1EP2
ECgene alternative splicing isoforms for
ATP5F1EP2

Expression for ATP5F1EP2 Gene

NURSA nuclear receptor signaling pathways regulating expression of ATP5F1EP2 Gene:

ATP5F1EP2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ATP5F1EP2 Gene

Orthologs for ATP5F1EP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ATP5F1EP2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ATP5EP2 34
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 92 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ATP5E 34 34
  • 90 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 90 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Atp5e 34
  • 88 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 82 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii atp5e 34
  • 63 (a)
OneToMany
Species where no ortholog for ATP5F1EP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ATP5F1EP2 Gene

ENSEMBL:
Gene Tree for ATP5F1EP2 (if available)
TreeFam:
Gene Tree for ATP5F1EP2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ATP5F1EP2: view image

Paralogs for ATP5F1EP2 Gene

No data available for Paralogs for ATP5F1EP2 Gene

Variants for ATP5F1EP2 Gene

Sequence variations from dbSNP and Humsavar for ATP5F1EP2 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1003152790 -- 27,944,425(+) A/C upstream_transcript_variant
rs1003790749 -- 27,944,093(+) G/C upstream_transcript_variant
rs1004277851 -- 27,943,589(+) A/G upstream_transcript_variant
rs1005732175 -- 27,944,142(+) C/T upstream_transcript_variant
rs1006031459 -- 27,943,249(+) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ATP5F1EP2 Gene

Variant ID Type Subtype PubMed ID
dgv538e212 CNV gain 25503493
esv2761780 CNV gain 21179565
esv3582294 CNV gain 25503493
esv3631625 CNV gain 21293372

Variation tolerance for ATP5F1EP2 Gene

Gene Damage Index Score: 1.20; 24.05% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ATP5F1EP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ATP5F1EP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ATP5F1EP2 Gene

Disorders for ATP5F1EP2 Gene

Additional Disease Information for ATP5F1EP2

No disorders were found for ATP5F1EP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ATP5F1EP2 Gene

Publications for ATP5F1EP2 Gene

  1. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J … Shi Y (Genes & development 2015) 3 58
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  3. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin BM … Amundadottir LT (Nature genetics 2014) 3 58
  4. Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. (PMID: 20833797) Zhao X … Jensen ON (Molecular & cellular proteomics : MCP 2011) 3 58
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for ATP5F1EP2 Gene

Sources for ATP5F1EP2 Gene

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