Aliases for ATP10B Gene
External Ids for ATP10B Gene
Previous GeneCards Identifiers for ATP10B Gene
GeneCards Summary for ATP10B Gene
ATP10B (ATPase Phospholipid Transporting 10B (Putative)) is a Protein Coding gene. Diseases associated with ATP10B include Cholestasis, Benign Recurrent Intrahepatic, 1 and Waardenburg Syndrome, Type 4C. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. Gene Ontology (GO) annotations related to this gene include nucleotide binding and cation-transporting ATPase activity. An important paralog of this gene is ATP10D.
UniProtKB/Swiss-Prot Summary for ATP10B Gene
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable).