Aliases for ATG9B Gene
External Ids for ATG9B Gene
Previous HGNC Symbols for ATG9B Gene
Previous GeneCards Identifiers for ATG9B Gene
This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
GeneCards Summary for ATG9B Gene
ATG9B (Autophagy Related 9B) is a Protein Coding gene. Diseases associated with ATG9B include Hypertension, Essential. Among its related pathways are Macroautophagy and Mitophagy - animal. An important paralog of this gene is ATG9A.
UniProtKB/Swiss-Prot Summary for ATG9B Gene
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).