Aliases for ATG9A Gene
External Ids for ATG9A Gene
Previous HGNC Symbols for ATG9A Gene
Previous GeneCards Identifiers for ATG9A Gene
GeneCards Summary for ATG9A Gene
ATG9A (Autophagy Related 9A) is a Protein Coding gene. Diseases associated with ATG9A include Age-Related Hearing Loss and Spastic Paraplegia 52, Autosomal Recessive. Among its related pathways are Macroautophagy and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include heme-copper terminal oxidase activity. An important paralog of this gene is ATG9B.
UniProtKB/Swiss-Prot Summary for ATG9A Gene
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.