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This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016] See more...
Aliases for ATG2B Gene
Aliases for ATG2B Gene
External Ids for ATG2B Gene
- HGNC: 20187
- NCBI Entrez Gene: 55102
- Ensembl: ENSG00000066739
- OMIM®: 616226
- UniProtKB/Swiss-Prot: Q96BY7
Previous HGNC Symbols for ATG2B Gene
- C14orf103
Previous GeneCards Identifiers for ATG2B Gene
- GC14M095817
- GC14M096747
- GC14M076932
Summaries for ATG2B Gene
-
This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016]
GeneCards Summary for ATG2B Gene
ATG2B (Autophagy Related 2B) is a Protein Coding gene. Among its related pathways are Pathways of neurodegeneration - multiple diseases and Autophagy Pathway. An important paralog of this gene is ATG2A.
UniProtKB/Swiss-Prot Summary for ATG2B Gene
-
Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion (PubMed:22219374). Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion (PubMed:31721365).
Additional gene information for ATG2B Gene
- HGNC (20187)
- NCBI Entrez Gene (55102)
- Ensembl (ENSG00000066739)
- OMIM® (616226)
- UniProtKB/Swiss-Prot (Q96BY7)
- Open Targets Platform(ENSG00000066739)
- Search for ATG2B at DataMed
- Search for ATG2B at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ATG2B Gene
Genomics for ATG2B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ATG2B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ATG2B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ATG2B
- Top Transcription factor binding sites by QIAGEN in the ATG2B gene promoter:
-
- COMP1
- FOXL1
- FOXO4
- GR
- GR-alpha
- Hlf
- HSF1 (long)
- HSF1short
- LyF-1
- Sox9
Genomic Locations for ATG2B Gene
Latest Assembly
- chr14:96,279,195-96,363,341
- (GRCh38/hg38)
- Size:
- 84,147 bases
- Orientation:
- Minus strand
Previous Assembly
- chr14:96,745,532-96,829,678
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 84,147 bases
- Orientation:
- Minus strand
- chr14:96,747,595-96,830,207
- (GRCh37/hg19 by Ensembl)
- Size:
- 82,613 bases
- Orientation:
- Minus strand
Genomic View for ATG2B Gene
Genes around ATG2B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.2 by HGNC
- 14q32.2 by Entrez Gene
- 14q32.2 by Ensembl
ATG2B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ATG2B Gene
Proteins for ATG2B Gene
-
Protein details for ATG2B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96BY7-ATG2B_HUMAN
- Recommended name:
- Autophagy-related protein 2 homolog B
- Protein Accession:
- Q96BY7
- Q6ZRE7
- Q96DQ3
- Q9NW80
Protein attributes for ATG2B Gene
- Size:
- 2078 amino acids
- Molecular mass:
- 232763 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA91504.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB70872.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305}; Sequence=BAC87363.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for ATG2B Gene
Post-translational modifications for ATG2B Gene
Other Protein References for ATG2B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences ATG2B Antibody
-
Custom Antibody ServicesOriGene Antibodies for ATG2B
- Novus Biologicals Antibodies for ATG2B
- Invitrogen Antibodies for ATG2B (AFLGC-ATG2B)
- antibodies-online: Show 10 available ATG2B Antibodies ranked by validation data
-
Boster Bio Antibodies for ATG2B
-
Custom Antibody ServicesProSci Antibodies for ATG2B
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ATG2B
- Origene Custom Protein Services for ATG2B
- Novus Biologicals proteins for ATG2B
Assay products for research
No data available for DME Specific Peptides for ATG2B Gene
Domains & Families for ATG2B Gene
Gene Families for ATG2B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transporters
Protein Domains for ATG2B Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ATG2B Gene
- GenScript: Design optimal peptide antigens:
-
- Autophagy-related protein 2 homolog B (ATG2B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96BY7- Family:
-
- Belongs to the ATG2 family.
Function for ATG2B Gene
Molecular function for ATG2B Gene
- UniProtKB/Swiss-Prot Function:
- Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion (PubMed:22219374). Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion (PubMed:31721365).
Phenotypes From GWAS Catalog for ATG2B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0032266 | phosphatidylinositol-3-phosphate binding | IBA | 21873635 |
| GO:0120013 | intermembrane lipid transfer activity | IDA | 31721365 |
Phenotypes for ATG2B Gene
- MGI mutant phenotypes for ATG2B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ATG2B:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ATG2B - Starting at $85 >
- * ATG2B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ATG2B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ATG2B
-
Santa Cruz Biotechnology (SCBT) CRISPR for ATG2B
miRNA for ATG2B Gene
- miRTarBase miRNAs that target ATG2B
-
- hsa-miR-130a-3p (MIRT006259)
- hsa-miR-421 (MIRT016131)
- hsa-miR-30d-5p (MIRT438869)
- hsa-miR-20a-5p (MIRT441164)
- hsa-miR-106b-5p (MIRT441165)
- hsa-miR-3692-3p (MIRT550922)
- hsa-miR-7159-5p (MIRT550923)
- hsa-miR-505-3p (MIRT550924)
- hsa-miR-4709-5p (MIRT550925)
- hsa-miR-4272 (MIRT550926)
- hsa-miR-154-5p (MIRT550927)
- hsa-miR-10a-3p (MIRT550928)
- hsa-miR-19b-3p (MIRT728273)
- hsa-miR-19a-3p (MIRT728274)
- hsa-miR-181d-5p (MIRT728275)
- hsa-miR-181b-5p (MIRT728276)
- hsa-miR-181c-5p (MIRT728277)
- hsa-miR-181a-5p (MIRT728278)
- hsa-miR-519d-3p (MIRT728279)
- hsa-miR-93-5p (MIRT728280)
- hsa-miR-17-5p (MIRT728281)
- hsa-miR-20b-5p (MIRT728282)
- hsa-miR-1303 (MIRT735027)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ATG2B
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ATG2B
Clone products for research
- Applied Biological Materials (abm): Clones for ATG2B - Starting at $45 >
- * ATG2B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ATG2B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ATG2B
Cell Lines for research
-
Horizon Cell Lines for ATG2B
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ATG2B Gene
Localization for ATG2B Gene
Subcellular locations from UniProtKB/Swiss-Prot for ATG2B Gene
- Preautophagosomal structure membrane. Peripheral membrane protein. Lipid droplet. Endoplasmic reticulum membrane. Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| lysosome | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000407 | phagophore assembly site | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005811 | lipid droplet | IEA | -- |
Pathways & Interactions for ATG2B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Pathways of neurodegeneration - multiple diseases | ||
| 2 | Autophagy - animal | ||
| 3 | Macroautophagy | ||
| 4 | Spinocerebellar ataxia | ||
| 5 | Autophagy Pathway | ||
Pathways by source for ATG2B Gene
1 Sino Biological pathway for ATG2B Gene
7 KEGG pathways for ATG2B Gene
Interacting Proteins for ATG2B Gene
GPS-Prot Interaction Network for ATG2B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000045 | autophagosome assembly | IBA | 21873635 |
| GO:0000422 | autophagy of mitochondrion | IBA | 21873635 |
| GO:0006914 | autophagy | IEA | -- |
| GO:0034727 | piecemeal microautophagy of the nucleus | IBA | 21873635 |
| GO:0044805 | late nucleophagy | IBA | 21873635 |
No data available for SIGNOR curated interactions for ATG2B Gene
Transcripts for ATG2B Gene
mRNA/cDNA for ATG2B Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000261834 1920 nts (view in UCSC)
- ENST00000359933 13162 nts (view in UCSC)
- ENST00000473234 550 nts (view in UCSC)
- ENST00000488421 522 nts (view in UCSC)
- ENST00000553643 482 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ATG2B - Starting at $85 >
- * ATG2B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ATG2B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ATG2B
-
Santa Cruz Biotechnology (SCBT) CRISPR for ATG2B
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ATG2B
- Browse OriGene Inhibitory RNA Products For ATG2B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ATG2B
Clone products for research
- Applied Biological Materials (abm): Clones for ATG2B - Starting at $45 >
- * ATG2B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ATG2B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ATG2B
Relevant External Links for ATG2B Gene
- GeneLoc Exon Structure for
- ATG2B
Expression for ATG2B Gene
This gene is overexpressed in Fetal Brain (12.0), Bone marrow mesenchymal stem cell (10.0), Frontal cortex (9.4), Retina (8.6), and Pancreas (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ATG2B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ATG2B
SOURCE GeneReport for Unigene cluster for ATG2B Gene:
Hs.168241Evidence on tissue expression from TISSUES for ATG2B Gene
- Liver(4.4)
- Skin(4.3)
- Nervous system(3.2)
Primer products for research
-
OriGene qPCR primer pairs for ATG2B
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ATG2B Gene
Orthologs for ATG2B Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ATG2B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ATG2B 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ATG2B 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ATG2B 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ATG2B 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Atg2b 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ATG2B 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ATG2B 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | atg2b 30 |
|
||
| Str.8303 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | ATG2B 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004092 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Atg2 30 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | atg-2 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ATG2 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.1201 31 |
|
OneToMany |
- Species where no ortholog for ATG2B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ATG2B Gene
- ENSEMBL:
- Gene Tree for ATG2B (if available)
- TreeFam:
- Gene Tree for ATG2B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ATG2B: view image
Paralogs for ATG2B Gene
Variants for ATG2B Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ATG2B Gene
| SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs114955360 | Benign: not provided | 96,303,229(-) |
C/T NM_018036.7(ATG2B):c.4869G>A (p.Pro1623=) |
SYNONYMOUS | |
| rs116026484 | Benign: not provided | 96,317,747(-) |
A/G NM_018036.7(ATG2B):c.2988T>C (p.Asn996=) |
SYNONYMOUS | |
| rs117507139 | Benign: not provided | 96,332,503(-) |
C/T NM_018036.7(ATG2B):c.1360G>A (p.Val454Met) |
MISSENSE | |
| rs142484701 | Benign: not provided | 96,332,343(-) |
G/A NM_018036.7(ATG2B):c.1430C>T (p.Pro477Leu) |
MISSENSE | |
| rs150538996 | Benign: not provided | 96,301,998(-) |
G/A NM_018036.7(ATG2B):c.5139+9C>T |
INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3635420 | CNV | gain | 21293372 |
Residual Variation Intolerance Score:
34.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.67;
78.49% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ATG2B Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ATG2B Gene
Disorders for ATG2B Gene
Additional Disease Information for ATG2B
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for ATG2B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ATG2B Gene
Publications for ATG2B Gene
- Human ATG2B possesses a lipid transfer activity which is accelerated by negatively charged lipids and WIPI4. (PMID: 31721365) Osawa T … Noda NN (Genes to cells : devoted to molecular & cellular mechanisms 2020) 3 4
- Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. (PMID: 22219374) Velikkakath AK … Mizushima N (Molecular biology of the cell 2012) 3 4
- miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells. (PMID: 22350415) Kovaleva V … Seiffert M (Cancer research 2012) 2 3
- Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. (PMID: 19197948) Kang MR … Lee SH (The Journal of pathology 2009) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for ATG2B Gene
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- High-throughput Antibody Production Service
- Protein Production Service
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- Browse ELISA Kits
- Invitrogen Antibodies for ATG2B (AFLGC-ATG2B)
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- antibodies-online: Show 10 available ATG2B Antibodies ranked by validation data
- antibodies-online: Search results for available ATG2B related products ranked by validation data
- antibodies-online: Search results for available ATG2B related products ranked by validation data
- Custom Antibody ServicesProSci Antibodies for ATG2B
- Search for ATG2B Proteins at ProSci
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- Browse GeneCopoeia Cell Lines
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Sources for ATG2B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
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- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
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- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
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- (108) GTR
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- (114) NINDS
- (115) NCBI Bookshelf
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- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
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- (140) HumanCyc
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- (143) Applied Biosystems
- (144) GlyConnect
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- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB