Aliases for ATG13 Gene
External Ids for ATG13 Gene
Previous HGNC Symbols for ATG13 Gene
Previous GeneCards Identifiers for ATG13 Gene
The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway. The encoded protein is essential for autophagosome formation and mitophagy. [provided by RefSeq, Oct 2016]
GeneCards Summary for ATG13 Gene
ATG13 (Autophagy Related 13) is a Protein Coding gene. Among its related pathways are Longevity regulating pathway and PI3K-AKT-mTOR signaling pathway and therapeutic opportunities. Gene Ontology (GO) annotations related to this gene include protein kinase binding.
UniProtKB/Swiss-Prot for ATG13 Gene
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.