Aliases for ATF7 Gene
Aliases for ATF7 Gene
External Ids for ATF7 Gene
- HGNC: 792
- Entrez Gene: 11016
- Ensembl: ENSG00000170653
- OMIM: 606371
- UniProtKB: P17544
Previous GeneCards Identifiers for ATF7 Gene
- GC12M053905
- GC12M054022
- GC12M053626
- GC12M052196
- GC12M050945
Summaries for ATF7 Gene
GeneCards Summary for ATF7 Gene
ATF7 (Activating Transcription Factor 7) is a Protein Coding gene. Diseases associated with ATF7 include Penicilliosis and Familial Atrial Fibrillation. Among its related pathways are ERK Signaling and TCR Signaling (Qiagen). Gene Ontology (GO) annotations related to this gene include nucleic acid binding and sequence-specific DNA binding. An important paralog of this gene is ENSG00000267281.
UniProtKB/Swiss-Prot for ATF7 Gene
-
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AG][AG]-3), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
-
Isoform 4 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
-
Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Additional gene information for ATF7 Gene
- Monarch Initiative
- Search for ATF7 at DataMed
- Search for ATF7 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ATF7 Gene
Genomics for ATF7 Gene
GeneHancer (GH) Regulatory Elements for ATF7 Gene
Promoters and enhancers for ATF7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ATF7 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ATF7 Gene
Genomic Locations for ATF7 Gene
- chr12:53,507,856-53,626,415
- (GRCh38/hg38)
- Size:
- 118,560 bases
- Orientation:
- Minus strand
- chr12:53,901,640-54,020,199
- (GRCh37/hg19)
Genomic View for ATF7 Gene
Genes around ATF7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.13 by Ensembl
- 12q13.13 by Entrez Gene
- 12q13.13 by HGNC
ATF7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ATF7 Gene
Proteins for ATF7 Gene
-
Protein details for ATF7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P17544-ATF7_HUMAN
- Recommended name:
- Cyclic AMP-dependent transcription factor ATF-7
- Protein Accession:
- P17544
- A5D6Y4
- B2RMP1
- B4DQL4
- Q13814
- Q8IVR8
- Q9UD83
Protein attributes for ATF7 Gene
- Size:
- 494 amino acids
- Molecular mass:
- 52967 Da
- Quaternary structure:
-
- Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members. Interacts with JNK2; the interaction does not phosphorylate ATF7 but acts as a docking site for other ATF-associated partners such as JUN family members. Interacts (via its transactivation domain) with TAF12 (isoforms TAFII15 and TAFII20); the interaction potentiates the transactivation activity (isoform TAFII20 only) and is inhibited by ATF7 sumoylation. Interacts with TAF4; the interaction inhibits the TAF12-dependent transactivation. Interacts with adenovirus 2 E1A; the interaction enhances the ATF7-mediated viral transactivation activity which requires the zinc-binding domains of both E1A and ATF7. Interacts with MAPK9; the interaction does not phosphorylate ATF7 but acts as a docking site for ATF7-associated partners such as JUN.
Protein Expression for ATF7 Gene
Post-translational modifications for ATF7 Gene
- On EGF stimulation, phosphorylated first on Thr-53 allowing subsequent phosphorylation on Thr-51. This latter phosphorylation prevents sumoylation, increases binding to TAF12 and enhances transcriptional activity.
- Sumoylation delays nuclear localization and inhibits transactivation activity through preventing binding to TAF12. RANBP2 appears to be the specific E3 ligase.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ATF7 Gene
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-
Abcam proteins for ATF7
Assay Products
No data available for DME Specific Peptides for ATF7 Gene
Domains & Families for ATF7 Gene
Gene Families for ATF7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Transcription factors
Protein Domains for ATF7 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ATF7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P17544- Family:
-
- Belongs to the bZIP family.
Function for ATF7 Gene
Molecular function for ATF7 Gene
- UniProtKB/Swiss-Prot Function:
- Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AG][AG]-3), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
- UniProtKB/Swiss-Prot Function:
- Isoform 4 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
- UniProtKB/Swiss-Prot Function:
- Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Phenotypes From GWAS Catalog for ATF7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA binding transcription factor activity | NAS,IEA | -- |
| GO:0005515 | protein binding | IPI | 10376527 |
| GO:0008134 | transcription factor binding | IDA | 10376527 |
| GO:0019899 | enzyme binding | IPI | 23382074 |
Phenotypes for ATF7 Gene
- MGI mutant phenotypes for ATF7:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ATF7:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased viability in esophageal squamous lineage
- Decreased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased shRNA abundance (Z-score < -2)
- Increased G1 DNA content
- G0/1 arrest
- Increased shRNA abundance (Z-score > 2)
- Increased Nanog expression
- Decreased viability
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-
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- Search ViGene Biosciences for ATF7
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Vectors and viruses for KO, Activation, Repression, and more
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Santa Cruz Biotechnology (SCBT) CRISPR for ATF7
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miRNA for ATF7 Gene
- miRTarBase miRNAs that target ATF7
Targeted motifs for ATF7 Gene
HOMER Transcription Factor Regulatory Elements motif ATF7
- Consensus sequence: NGRTGACGTCAY Submotif: canonical Cell Type: 3T3L1 GEO ID: GSE56872
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Clone Products
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-
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
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Horizon Cell Lines for ATF7
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and Transcription Factor Targets for ATF7 Gene
Localization for ATF7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ATF7 Gene
- Nucleus. Nucleus, nucleoplasm. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.
- Isoform 5: Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
- Cytosol (2)
- Nucleus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | NAS | 8288576 |
| GO:0005654 | nucleoplasm | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0034399 | nuclear periphery | IDA | 17264123 |
Pathways & Interactions for ATF7 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | ERK Signaling |
.58
|
.49
|
| 2 | Ceramide Pathway |
.32
|
|
| 3 | Sertoli-Sertoli Cell Junction Dynamics | ||
| 4 | Toll Comparative Pathway |
.34
|
|
| 5 | TCR Signaling (Qiagen) | ||
Pathways by source for ATF7 Gene
1 BioSystems pathway for ATF7 Gene
9 Qiagen pathways for ATF7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IDA | 8288576 |
| GO:0016032 | viral process | IEA | -- |
No data available for SIGNOR curated interactions for ATF7 Gene
Transcripts for ATF7 Gene
mRNA/cDNA for ATF7 Gene
- (7) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (52) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ATF7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ATF7
- genomics-online: gRNA clones - Search results for 99 available AFT7 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ATF7
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miRNA Products
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Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ATF7
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-
ViGene Biosciences ready-to-package AAV shRNAs for ATF7 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ATF7
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ATF7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - |
Expression for ATF7 Gene
This gene is overexpressed in NK cells (15.7), Fetal testis (13.4), Fetal ovary (12.3), and Testis (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ATF7 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ATF7 Gene:
ATF7SOURCE GeneReport for Unigene cluster for ATF7 Gene:
Hs.12286mRNA Expression by UniProt/SwissProt for ATF7 Gene:
P17544-ATF7_HUMAN
Tissue specificity:
Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.
Evidence on tissue expression from TISSUES for ATF7 Gene
- Nervous system(4.6)
- Intestine(4.2)
- Liver(4.2)
Primer Products
-
OriGene qPCR primer pairs for ATF7
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ATF7 Gene
Orthologs for ATF7 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ATF7 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
| ATF7 33 |
|
||||
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| ATF7 33 |
|
||||
| mouse (Mus musculus) |
Mammalia | ATF7 34 |
|
ManyToMany | |
| Atf7 33 16 34 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Atf7 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| ATF7 33 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | atf7 33 |
|
||
| Str.18007 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | atf7a 33 34 |
|
||
| atf7b 34 |
|
ManyToMany | |||
| wufa97a09 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9788 33 |
|
- Species where no ortholog for ATF7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ATF7 Gene
(2) SIMAP similar genes for ATF7 Gene using alignment to 4 proteins:
Variants for ATF7 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000002990 | -- | 53,527,390(-) | G/A | genic_downstream_transcript_variant, intron_variant | |
| rs1000003316 | -- | 53,609,698(-) | C/T | intron_variant | |
| rs1000013048 | -- | 53,579,531(-) | G/A | intron_variant | |
| rs1000061032 | -- | 53,615,984(-) | T/G | intron_variant | |
| rs1000066596 | -- | 53,525,222(-) | G/A | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2672386 | CNV | deletion | 23128226 |
| esv2673908 | CNV | deletion | 23128226 |
| esv2745909 | CNV | deletion | 23290073 |
| esv3629542 | CNV | loss | 21293372 |
| esv3629543 | CNV | loss | 21293372 |
| esv3629544 | CNV | loss | 21293372 |
| nsv1113484 | CNV | deletion | 24896259 |
| nsv1122736 | CNV | deletion | 24896259 |
| nsv526791 | CNV | gain | 19592680 |
| nsv53289 | CNV | insertion | 16902084 |
| nsv715 | CNV | deletion | 18451855 |
| nsv973988 | CNV | duplication | 23825009 |
| nsv975496 | CNV | duplication | 23825009 |
| nsv983486 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
31.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.15;
3.30% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ATF7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ATF7
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ATF7 Gene
Disorders for ATF7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| penicilliosis |
|
|
| familial atrial fibrillation |
|
|
Search ATF7 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ATF7
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ATF7 Gene
Publications for ATF7 Gene
- A functional interaction between ATF7 and TAF12 that is modulated by TAF4. (PMID: 15735663) Hamard PJ … Chatton B (Oncogene 2005) 3 4 22 58
- Role of the ATFa/JNK2 complex in Jun activation. (PMID: 10376527) De Graeve F … Chatton B (Oncogene 1999) 3 4 22 58
- Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells. (PMID: 1694576) Gaire M … Kedinger C (Nucleic acids research 1990) 2 3 4 58
- A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity. (PMID: 21858082) Diring J … Chatton B (PloS one 2011) 3 4 58
- Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. (PMID: 21998595) N'Diaye A … Haiman CA (PLoS genetics 2011) 3 44 58
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- Compare Top AFT7 Proteins
- Quality Products:
- GeneTex ATF7 antibody for ATF7
- Search GeneTex for Proteins for ATF7
- ViGene Biosciences adenoviral particle packaged cDNA for ATF7 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ATF7 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ATF7 gene
- Search ViGene Biosciences for ATF7
- Santa Cruz Biotechnology (SCBT) Antibodies for ATF7
- Search Santa Cruz Biotechnology (SCBT) for ATF7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ATF7
- Horizon Cell Lines for ATF7
- genomics-online: cdna clones - Search results for 99 available AFT7 gene related products
- Overview of 99 available AFT7 gene related products
- orf clones - Search results for 99 available AFT7 gene related products
- Overview of 99 available AFT7 gene related products
- genomics-online: gRNA clones - Search results for 99 available AFT7 gene related products
- Overview of 99 available AFT7 gene related products
- genomics-online: primer clones - Search results for 99 available AFT7 gene related products
- Overview of 99 available AFT7 gene related products
- genomics-online: shRNA clones - Search results for 99 available AFT7 gene related products
- Overview of 99 available AFT7 gene related products
Sources for ATF7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems