Aliases for ATF5 Gene
Aliases for ATF5 Gene
External Ids for ATF5 Gene
- HGNC: 790
- Entrez Gene: 22809
- Ensembl: ENSG00000169136
- OMIM: 606398
- UniProtKB: Q9Y2D1
Previous GeneCards Identifiers for ATF5 Gene
- GC19P051090
- GC19P050800
- GC19P055108
- GC19P055124
- GC19P050431
- GC19P046808
Summaries for ATF5 Gene
GeneCards Summary for ATF5 Gene
ATF5 (Activating Transcription Factor 5) is a Protein Coding gene. Diseases associated with ATF5 include Triple-Receptor Negative Breast Cancer and West Nile Fever. Among its related pathways are Signaling events mediated by PRL and ERK Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription corepressor activity. An important paralog of this gene is ATF4.
UniProtKB/Swiss-Prot for ATF5 Gene
-
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), ATF5-specific response element (ARE) (consensus: 5-C[CT]TCT[CT]CCTT[AT]-3) but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation (PubMed:10373550, PubMed:15358120, PubMed:21212266, PubMed:20654631). Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 (PubMed:15358120). Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate (By similarity). Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation (By similarity). Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes (By similarity). May be involved in osteogenic differentiation (PubMed:22442021). Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1. Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1 (PubMed:21791614). Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent (By similarity). Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver (PubMed:18332083). In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase (PubMed:22528486, PubMed:18701499). May act as a negative regulator of IL1B transduction pathway in liver (PubMed:24379400). Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members (PubMed:25512613). Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation (PubMed:24216764). Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner. Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material (PubMed:26213385).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ATF5 Gene
Genomics for ATF5 Gene
GeneHancer (GH) Regulatory Elements for ATF5 Gene
Promoters and enhancers for ATF5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ATF5 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ATF5 Gene
Genomic Locations for ATF5 Gene
- chr19:49,928,702-49,933,936
- (GRCh38/hg38)
- Size:
- 5,235 bases
- Orientation:
- Plus strand
- chr19:50,431,959-50,437,193
- (GRCh37/hg19)
Genomic View for ATF5 Gene
Genes around ATF5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
ATF5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ATF5 Gene
Proteins for ATF5 Gene
-
Protein details for ATF5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2D1-ATF5_HUMAN
- Recommended name:
- Cyclic AMP-dependent transcription factor ATF-5
- Protein Accession:
- Q9Y2D1
- B3KND3
- Q9BSA1
- Q9UNQ3
Protein attributes for ATF5 Gene
- Size:
- 282 amino acids
- Molecular mass:
- 30674 Da
- Quaternary structure:
-
- Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2 (PubMed:15358120). Interacts with HSPA1A or HSPA1B; the interaction protects ATF5 from degradation via proteasome-dependent and caspase-dependent processes. Interacts (via C-terminal region) with NPM1 (via C-terminal region); the interaction leads to loss of association between HSPA1A or HSPA1B and ATF5 and promotes ATF5 degradation via proteasome-dependent and caspase-dependent processes (PubMed:22528486, PubMed:24379400). Interacts with NLK; the interaction stabilizes ATF5 at the protein level in a kinase-independent manner (PubMed:25512613). Interacts with alpha-tubulin, gamma-tubulin members TUBGCP2 and TUBGCP4, PCNT; the ATF5:PCNT:polyglutamylated tubulin (PGT) tripartite unites the mother centriole and the pericentriolar material (PCM) in the centrosome (PubMed:26213385). Interacts with CEBPB and EP300; EP300 is required for ATF5 and CEBPB interaction and DNA binding (By similarity).
Post-translational modifications for ATF5 Gene
- Acetylated at Lys-29 by EP300, the acetylation enhances the interaction with CEBPB, DNA-binding and transactivation activity.
- Phosphorylated by NLK, probably at Ser-92, Thr-94, Ser-126 and Ser-190.
- Ubiquitinated by CDC34 and UBE2B in order to be degraded by the proteasome. Cisplatin inhibits ubiquitination and proteasome-mediated degradation by inhibiting the interaction with CDC34 (PubMed:18458088). Ubiquitination and degradation by the proteasome are inhibited by NLK in a kinase-independent manner (PubMed:25512613).
Other Protein References for ATF5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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Protein Products
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-
Abcam proteins for ATF5
Assay Products
No data available for DME Specific Peptides for ATF5 Gene
Domains & Families for ATF5 Gene
Gene Families for ATF5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ATF5 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ATF5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y2D1- Family:
-
- Belongs to the bZIP family.
Function for ATF5 Gene
Molecular function for ATF5 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), ATF5-specific response element (ARE) (consensus: 5-C[CT]TCT[CT]CCTT[AT]-3) but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation (PubMed:10373550, PubMed:15358120, PubMed:21212266, PubMed:20654631). Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 (PubMed:15358120). Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate (By similarity). Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation (By similarity). Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes (By similarity). May be involved in osteogenic differentiation (PubMed:22442021). Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1. Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1 (PubMed:21791614). Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent (By similarity). Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver (PubMed:18332083). In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase (PubMed:22528486, PubMed:18701499). May act as a negative regulator of IL1B transduction pathway in liver (PubMed:24379400). Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members (PubMed:25512613). Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation (PubMed:24216764). Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner. Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material (PubMed:26213385).
- UniProtKB/Swiss-Prot Induction:
- Down-regulated by pro-apoptotic stimuli (PubMed:21212266). However, the pro-apoptotic cisplatin increases protein levels by inhibiting polyubiquitination (PubMed:18458088). IL1B increases protein levels through protein stabilization and increase of translation efficiency (PubMed:24379400).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IMP | 15890932 |
| GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | IC | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003682 | chromatin binding | IDA,IEA | 21212266 |
| GO:0003700 | DNA binding transcription factor activity | ISS,IEA | -- |
Phenotypes for ATF5 Gene
- MGI mutant phenotypes for ATF5:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ATF5:
Animal Model Products
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-
-
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- Search ViGene Biosciences for ATF5
CRISPR Products
-
OriGene CRISPR knockouts for ATF5
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- Overview of 101 available ATF5 gene related products
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Vectors and viruses for KO, Activation, Repression, and more
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miRNA for ATF5 Gene
- miRTarBase miRNAs that target ATF5
-
- hsa-mir-7-5p (MIRT025724)
- hsa-mir-222-3p (MIRT046831)
- hsa-mir-142-3p (MIRT151995)
- hsa-mir-519e-5p (MIRT716531)
- hsa-mir-515-5p (MIRT716532)
- hsa-mir-4749-3p (MIRT716533)
- hsa-mir-5695 (MIRT716534)
- hsa-mir-519d-5p (MIRT716535)
- hsa-mir-6892-3p (MIRT716536)
- hsa-mir-6769a-3p (MIRT716537)
- hsa-mir-6856-3p (MIRT716538)
miRNA Products
- Search ViGene Biosciences for ATF5
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for ATF5 gene
Clone Products
- Sino Biological Human cDNA Clone for ATF5
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- VectorBuilder custom plasmid, inducible vectors for ATF5
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ATF5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ATF5
-
ViGene Biosciences adenoviral particle packaged cDNA for ATF5 gene
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ATF5 Gene
Localization for ATF5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ATF5 Gene
- Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. {ECO:0000269 PubMed:26213385}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| endoplasmic reticulum | 1 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 22528486 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005667 | transcription factor complex | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IDA | 26213385 |
Pathways & Interactions for ATF5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | ERK Signaling |
.58
|
.49
|
| 2 | Ceramide Pathway |
.32
|
|
| 3 | Sertoli-Sertoli Cell Junction Dynamics | ||
| 4 | Toll Comparative Pathway |
.34
|
|
| 5 | TCR Signaling (Qiagen) | ||
Pathways by source for ATF5 Gene
3 BioSystems pathways for ATF5 Gene
9 Qiagen pathways for ATF5 Gene
Interacting Proteins for ATF5 Gene
Selected Interacting proteins:
ENSP00000396954
Q9Y2D1-ATF5_HUMAN
for ATF5 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IDA | 20654631 |
| GO:0006357 | regulation of transcription by RNA polymerase II | TAS,IEA | 10373550 |
| GO:0006366 | transcription by RNA polymerase II | IEA | -- |
| GO:0007623 | circadian rhythm | IEA | -- |
No data available for SIGNOR curated interactions for ATF5 Gene
Transcripts for ATF5 Gene
mRNA/cDNA for ATF5 Gene
- (4) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (370) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ATF5 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ATF5
- genomics-online: gRNA clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
- Applied Biological Materials CRISPR for ATF5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ATF5
- GenScript: Design CRISPR guide RNA sequences for ATF5
miRNA Products
- Search ViGene Biosciences for ATF5
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ATF5
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- genomics-online: shRNA clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ATF5 gene
Clone Products
- Sino Biological Human cDNA Clone for ATF5
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- VectorBuilder custom plasmid, inducible vectors for ATF5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ATF5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ATF5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ATF5 Gene
mRNA differential expression in normal tissues according to GTEx for ATF5 Gene
This gene is overexpressed in Liver (x34.1).
NURSA nuclear receptor signaling pathways regulating expression of ATF5 Gene:
ATF5SOURCE GeneReport for Unigene cluster for ATF5 Gene:
Hs.9754mRNA Expression by UniProt/SwissProt for ATF5 Gene:
Q9Y2D1-ATF5_HUMAN
Tissue specificity:
Widely expressed with higher expression levels in liver.
Evidence on tissue expression from TISSUES for ATF5 Gene
- Nervous system(4.6)
- Liver(4)
- Eye(2.4)
Primer Products
-
OriGene qPCR primer pairs for ATF5
-
OriGene qPCR primer pairs and template standards for ATF5
- genomics-online: primer clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ATF5 Gene
Orthologs for ATF5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ATF5 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ATF5 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ATF5 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Atf5 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Atf5 33 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ATF5 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.511 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.15540 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | atf5a 34 |
|
OneToMany | |
| atf5b 34 |
|
OneToMany | |||
| wufc14a10 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2402 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2035 34 |
|
OneToMany |
- Species where no ortholog for ATF5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ATF5 Gene
Variants for ATF5 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000223412 | -- | 49,932,306(+) | GTTGTTTT/GTTGTTTTGTTGTTTT | intron_variant | |
| rs1000359557 | -- | 49,930,602(+) | C/G | intron_variant | |
| rs1000913718 | -- | 49,929,422(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001272530 | -- | 49,929,717(+) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001661048 | -- | 49,930,171(+) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv9739 | CNV | gain+loss | 18304495 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv7309 | OTHER | inversion | 18451855 |
| nsv579911 | CNV | gain | 21841781 |
| nsv579910 | CNV | gain | 21841781 |
| nsv458720 | CNV | gain | 19166990 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv1065648 | CNV | gain | 25217958 |
| nsv1058623 | CNV | gain | 25217958 |
| esv3644630 | CNV | gain | 21293372 |
| dgv54n68 | CNV | loss | 17160897 |
| dgv53n68 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
77.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.83;
47.84% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ATF5 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ATF5 Gene
Disorders for ATF5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| triple-receptor negative breast cancer |
|
|
| west nile fever |
|
|
Search ATF5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ATF5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ATF5 Gene
Publications for ATF5 Gene
- Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. (PMID: 10373550) Pati D … Plon SE (Molecular and cellular biology 1999) 2 3 4 58
- ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole. (PMID: 26213385) Madarampalli B … Liu DX (Cell 2015) 3 4 58
- Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway. (PMID: 25512613) Zhang ZY … Zhang XD (Molecular and cellular biology 2015) 3 4 58
- N-terminal hydrophobic amino acids of activating transcription factor 5 (ATF5) protein confer interleukin 1β (IL-1β)-induced stabilization. (PMID: 24379400) Abe T … Takahashi Y (The Journal of biological chemistry 2014) 3 4 58
- p300-dependent acetylation of activating transcription factor 5 enhances C/EBPβ transactivation of C/EBPα during 3T3-L1 differentiation. (PMID: 24216764) Zhao Y … Li X (Molecular and cellular biology 2014) 3 4 58
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- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ATF5
- Sino Biological Human cDNA Clone for ATF5
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ATF5
- Novus Biologicals lysates and proteins for ATF5
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for ATF5
- Abcam proteins for ATF5
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ATF5
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for ATF5
- VectorBuilder custom plasmid, inducible vectors for ATF5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ATF5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 85 available ATF5 Antibodies ranked by validation data
- Compare Top ATF5 Antibodies
- antibodies-online: Search results for 9 available ATF5 Elisa Kits ranked by validation data
- Compare Top ATF5 Elisa Kits
- antibodies-online: Search results for 4 available ATF5 Proteins ranked by validation data
- Compare Top ATF5 Proteins
- GeneTex ATF5 antibody for ATF5
- Search GeneTex for Proteins for ATF5
- ViGene Biosciences adenoviral particle packaged cDNA for ATF5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ATF5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ATF5 gene
- Search ViGene Biosciences for ATF5
- Santa Cruz Biotechnology (SCBT) Antibodies for ATF5
- Search Santa Cruz Biotechnology (SCBT) for ATF5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ATF5
- Horizon Cell Lines for ATF5
- genomics-online: cdna clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
- orf clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
- genomics-online: gRNA clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
- genomics-online: primer clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
- genomics-online: shRNA clones - Search results for 101 available ATF5 gene related products
- Overview of 101 available ATF5 gene related products
Sources for ATF5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew