Aliases for ATAD1 Gene
External Ids for ATAD1 Gene
Previous GeneCards Identifiers for ATAD1 Gene
GeneCards Summary for ATAD1 Gene
ATAD1 (ATPase Family AAA Domain Containing 1) is a Protein Coding gene. Diseases associated with ATAD1 include Hyperekplexia 4 and Hyperekplexia. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule-severing ATPase activity. An important paralog of this gene is VPS4B.
UniProtKB/Swiss-Prot Summary for ATAD1 Gene
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).